Results 1 to 10 of about 82,569 (97)

A plant NLR receptor employs ABA central regulator PP2C-SnRK2 to activate antiviral immunity [PDF]

Nature Communications
Defence against pathogens relies on intracellular nucleotide-binding, leucine-rich repeat immune receptors (NLRs) in plants. Hormone signaling including abscisic acid (ABA) pathways are activated by NLRs and play pivotal roles in defence against ...
Shen Huang, Chunli Wang, Zixuan Ding, Yaqian Zhao, Jing Dai, Jia Li, Haining Huang, Tongkai Wang, Min Zhu, Mingfeng Feng, Yinghua Ji, Zhongkai Zhang, Xiaorong Tao   +12 more
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Genome-wide identification and analysis of the NLR gene family in Medicago ruthenica

Frontiers in Genetics, 2023
Medicago ruthenica, important forage in the legume family, possesses high nutritional value and carries abundant tolerance genes. This study used whole-genome data of M.
Chunyan Tong, Chunyan Tong, Yutong Zhang, Yutong Zhang, Fengling Shi, Fengling Shi   +5 more
doaj   +1 more source

Evaluation of Nod-like receptor (NLR) effector domain interactions. [PDF]

PLoS ONE, 2009
Members of the Nod-like receptor (NLR) family recognize intracellular pathogens and recruit a variety of effector molecules, including pro-caspases and kinases, which in turn are implicated in cytokine processing and NF-kappaB activation.In order to ...
Roland N Wagner, Martina Proell, Thomas A Kufer, Robert Schwarzenbacher   +3 more
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Study to evaluate the relationship between receptor expression and clinical parameters in subjects with glioblastoma

Biomedical and Biotechnology Research Journal, 2023
Background: The most frequent and most aggressive primary brain tumor, glioblastoma (GBM) has an extremely poor prognosis. Several studies have shown the involvement of sex hormonal receptors and growth factor receptors in the onset of GBM.
K Ashwini, Jayaprakash Shetty, Kishan Prasad, Shilpa S Shetty, Ananthan Raghotham, Vijith Shetty, Praveen Kumar Shetty, N Suchetha Kumari   +7 more
doaj   +1 more source

A Meta-Analysis Reveals Opposite Effects of Biotic and Abiotic Stresses on Transcript Levels of Arabidopsis Intracellular Immune Receptor Genes

Frontiers in Plant Science, 2021
Plant intracellular immune receptor NLR (nucleotide-binding leucine-rich repeat) proteins sense the presence of pathogens and trigger strong and robust immune responses.
Leiyun Yang, Zhixue Wang, Jian Hua
doaj   +1 more source

Wheat Disease Resistance Genes and Their Diversification Through Integrated Domain Fusions

Frontiers in Genetics, 2020
Plants are in a constant evolutionary arms race with their pathogens. At the molecular level, the plant nucleotide-binding leucine-rich repeat receptors (NLRs) family has coevolved with rapidly evolving pathogen effectors.
Ethan J. Andersen, Madhav P. Nepal, Jordan M. Purintun, Dillon Nelson, Glykeria Mermigka, Panagiotis F. Sarris, Panagiotis F. Sarris, Panagiotis F. Sarris   +7 more
doaj   +1 more source

Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome. [PDF]

PLoS Pathogens, 2012
NOD-like receptor (NLR) proteins (Nlrps) are cytosolic sensors responsible for detection of pathogen and danger-associated molecular patterns through unknown mechanisms.
Jonathan L Levinsohn, Zachary L Newman, Kristina A Hellmich, Rasem Fattah, Matthew A Getz, Shihui Liu, Inka Sastalla, Stephen H Leppla, Mahtab Moayeri   +8 more
doaj   +1 more source

Prognostic Value of Pretreatment Neutrophil-to-Lymphocyte Ratio in HER2-Positive Metastatic Breast Cancer

Current Oncology, 2022
This study aimed to examine the prognostic value of the neutrophil-to-lymphocyte ratio (NLR) and other clinicopathological features in HER2+ MBC patients who received first-line anti-HER2 therapy.
Bin Shao, Xiaoran Liu, Huiping Li, Guohong Song, Lijun Di, Hanfang Jiang, Ying Yan, Ruyan Zhang, Ran Ran, Jiayang Zhang, Yaxin Liu, Huan Wang, Jing Wang   +12 more
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A novel conserved mechanism for plant NLR protein pairs: the ‘integrated decoy’ hypothesis

Frontiers in Plant Science, 2014
Plant immunity is often triggered by the specific recognition of pathogen effectors by intracellular nucleotide-binding, leucine-rich repeat (NLR) receptors.
Stella ecesari, Stella ecesari, Maud eBernoux, Philippe eMoncuquet, Thomas eKroj, Peter N Dodds   +5 more
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Plant pathogens convergently evolved to counteract redundant nodes of an NLR immune receptor network.

PLoS Biology, 2021
In plants, nucleotide-binding domain and leucine-rich repeat (NLR)-containing proteins can form receptor networks to confer hypersensitive cell death and innate immunity.
Lida Derevnina, Mauricio P Contreras, Hiroaki Adachi, Jessica Upson, Angel Vergara Cruces, Rongrong Xie, Jan Skłenar, Frank L H Menke, Sam T Mugford, Dan MacLean, Wenbo Ma, Saskia A Hogenhout, Aska Goverse, Abbas Maqbool, Chih-Hang Wu, Sophien Kamoun   +15 more
doaj   +1 more source