Results 291 to 300 of about 131,202 (338)

Quercetin and Allopurinol Ameliorate Kidney Injury in STZ-Treated Rats with Regulation of Renal NLRP3 Inflammasome Activation and Lipid Accumulation

, 2012
Chuang Wang, Ying Pan, Qingyu Zhang, Fu‐Meng Wang, Ling‐Dong Kong   +4 more
openalex   +2 more sources

<i>Salmonella</i>-NLRP3 Inflammasome Crosstalk: Host Defense Activation Versus Bacterial Immune Evasion Strategies. [PDF]

J Inflamm Res
Li Y, Xu Y, Jin C, Qiu J, Jiao X, Pan Z, Guo Y.   +6 more
europepmc   +1 more source

SGLT2 Inhibition by Enavogliflozin Significantly Reduces Aβ Pathology and Restores Cognitive Function via Upregulation of Microglial AMPK Signaling in 5XFAD Mouse Model of Alzheimer's Disease

Aging Cell, EarlyView.
SGLT2 inhibition with Enavogliflozin significantly improves cognitive function and reduces Aβ pathology in the 5XFAD mouse model of Alzheimer's disease. Through AMPK activation, Enavogliflozin enhances microglial mitochondrial function and Aβ phagocytosis while reducing neuroinflammation.
Jihui Han, Jaehoon Song, Eun Sun Jung, Ji Won Choi, Hye Young Ji, Inhee Mook‐Jung   +5 more
wiley   +1 more source

Multiple Binding Sites on the Pyrin Domain of ASC Protein Allow Self-association and Interaction with NLRP3 Protein

, 2012
Parimala R. Vajjhala, Ruth Mirams, Justine M. Hill   +2 more
openalex   +1 more source

Human dental pulp stem cells attenuate airway inflammation in mice with PM_2.5-induced asthma exacerbation by inhibiting the pyroptosis pathway. [PDF]

Stem Cell Res Ther
Liu J, Chen Y, Li Z, Li Z, Lyu F, Wang F, Wang A, Liu Z, Liao X, Wu J.   +9 more
europepmc   +1 more source

Progression and topographic subtypes of Terrien marginal degeneration

Acta Ophthalmologica, EarlyView.
Abstract Purpose To report long‐term outcomes and to search for immunological and genetic risk factors in Terrien marginal degeneration (TMD). Methods Retrospective, in part prospective, hospital‐based longitudinal follow‐up study of 32 eyes of 16 Finnish patients from 2012 to 2023. Median follow‐up was 7.3 years (range, 0.3–15.2).
Minna Ruutila, Pauliina Repo, Annamari T. Immonen, Joni A. Turunen, Marja‐Liisa Lokki, A. Inkeri Lokki, Jukka Moilanen, Kari Krootila, Tero T. Kivelä   +8 more
wiley   +1 more source

Knockdown NEK7 stimulates anti-tumor immune responses by NLRP3/PD-L1 signaling in esophageal cancer. [PDF]

Cancer Immunol Immunother
Wang L, Cheng Y, Li W, Wang J, Liu Z, Xiang Y, Liu X, Wang K, Yan D.   +8 more
europepmc   +1 more source

Protein tyrosine phosphatases as emerging targets for cancer immunotherapy

British Journal of Pharmacology, EarlyView.
Abstract Contemporary strategies in cancer immunotherapy, despite remarkable success, remain constrained by inherent limitations such as suboptimal patient responses, the emergence of drug resistance, and the manifestation of pronounced adverse effects. Consequently, the need for alternative strategies for immunotherapy becomes clear.
Zihan Qu, Jiajun Dong, Zhong‐Yin Zhang
wiley   +1 more source

A role for the NLRP3 inflammasome in metabolic diseases—did Warburg miss inflammation?

, 2012
Haitao Wen, Jenny P.‐Y. Ting, Luke O'neill   +2 more
openalex   +2 more sources