Results 201 to 210 of about 102,344 (304)

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

Food Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso, A. M. Abd El‐Aty, Kwaku Amoah, Xianghong Ju   +3 more
wiley   +1 more source

NOX2 deficiency exacerbates lupus nephritis through activation of NLRP3 inflammasome in neutrophils. [PDF]

J Biomed Sci
Wu CH, Lin FY, Lin MS, Chan TY, Chen YR, Cheng HC, Hsu CK, Chen CA, Chen PC, Cheng SM, Hwang DY, Sung JM, Tsai YS, Ling P, Shieh CC.   +14 more
europepmc   +1 more source

Inhibition of ERK5 activity ameliorates osteoarthritis by suppressing NLRP3 inflammasome-mediated chondrocyte pyroptosis. [PDF]

Bone Res
Zhang B, Fang P, Long J, Su D, Liu H, Weng R, Chen G, Chen Y, Chen G, Liao Z, Zhou T, Chen S, Su P, Xu C.   +13 more
europepmc   +1 more source

Cofilin-1 is a redox-sensitive guard of the NLRP3 inflammasome. [PDF]

Nat Immunol
Park YH, Batu ED, Matthiasardottir B, Kim Y, Akkaya-Ulum YZ, Kastner DL, Chae JJ.   +6 more
europepmc   +1 more source

Soyeom-Jetong mixture attenuates NLRP3 inflammasome-mediated inflammation. [PDF]

Front Pharmacol
Ye Q, Lee S, Park YC, Kim MS, Kim W, Jin JS, Kim DK, Jang S, Lee S, Lee N, Lee S, Seo BK, Kim MS, Kim Y, An D, Seo S, Lee D, Kim H, Park YH, Lee Y, Baek YH.   +20 more
europepmc   +1 more source

ANGPT1-GABARAP axis modulates NLRP3 inflammasome-mediated pyroptosis in Crohn's disease. [PDF]

Front Immunol
Li Y, He J, Gao P, Fu Z, Guo Y, Gao H, Li C, Zhang X.   +7 more
europepmc   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Loganin Attenuates Psoriasis-Like Inflammation by Regulating the NLRP3 Inflammasome-SIRT1 Axis in Keratinocytes. [PDF]

J Clin Pract Res
Çakır M, Açıkgöz E.
europepmc   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

Colchicine attenuates kidney injury by modulating the NLRP3 inflammasome pathway. [PDF]

Mol Med
Kim G, Heo GY, Nam BY, Cho Y, Yu JW, Park CH, Kim HW, Park JT, Yoo TH, Kang SW, Han SH.   +10 more
europepmc   +1 more source