Results 131 to 140 of about 149,179 (263)

Vaspin identified as a DNA‐binding serpin with functional consequences for protease inhibition

open access: yesThe FEBS Journal, EarlyView.
Vaspin is a serpin that is expressed in skin, adipose tissue, and liver. It binds to single‐ and double‐stranded DNA with high affinity. This binding is unaffected by mutation of the known heparin‐binding site, accelerates the inhibition of the inflammatory protease KLK7, and may contribute to vaspin's nuclear localization.
Kevin Möhlis   +9 more
wiley   +1 more source

Structural investigation of human U6 snRNA recognition by spliceosomal recycling factor SART3 RNA recognition motifs

open access: yesThe FEBS Journal, EarlyView.
Human SART3 has two RRM domains to engage with U6 snRNA for spliceosome recycling. This study reports solution structures of SART3 RRM domains and investigates the interaction between RRM and U6 snRNA. SART3 binds to the asymmetric bulge of U6 snRNA as a dimer via conserved positively charged surfaces.
Iktae Kim   +8 more
wiley   +1 more source

The importin‐alpha superfamily engages in ethylene signaling by shuttling ETHYLENE INSENSITIVE 2 from the endoplasmic reticulum to the nucleus

open access: yesThe FEBS Journal, EarlyView.
The plant hormone ethylene regulates plant growth, ripening, senescence, and stress responses. The hormonal signal transmission, from receptors at the ER membrane to the transcriptional regulators in the nucleus, is still not completely understood.
Fabian Wynen   +7 more
wiley   +1 more source

A comprehensive overview of yeast libraries and their role in advancing cell biology

open access: yesThe FEBS Journal, EarlyView.
Systematic, genome‐wide yeast mutant libraries have revolutionized systems and cell biology. By allowing high‐throughput interrogation of every gene and protein, they have defined gene essentiality, charted protein localization, illuminated function, mapped interactions, and more.
Din Baruch, Maya Schuldiner, Ofir Klein
wiley   +1 more source

Identification and Estimation of Large Network Games with Private Link Information

open access: yesInternational Economic Review, EarlyView.
ABSTRACT We study the identification and estimation of large network games in which individuals choose continuous actions while holding private information about their links and payoffs. Extending the framework of Galeotti et al., we build a tractable empirical model of such network games and show that the parameters in individual payoffs are ...
Hülya Eraslan, Xun Tang
wiley   +1 more source

Growth and age differences between two male alternative reproductive tactics in the plainfin midshipman

open access: yesJournal of Fish Biology, EarlyView.
Abstract The plainfin midshipman (Porichthys notatus Girard, 1854) is a toadfish with two distinct reproductive male tactics: ‘guarder males’ and ‘sneaker males’. These two tactics are anatomically, physiologically and behaviourally distinct from one another at sexual maturity, but it remained unclear whether these two male types remain fixed or ...
Micah J. Quindazzi   +4 more
wiley   +1 more source

Biological aspects and population dynamics of the European pilchard Sardina pilchardus (Walbaum, 1792) in the southeastern Mediterranean waters

open access: yesJournal of Fish Biology, EarlyView.
Abstract The European pilchard, Sardina pilchardus, is a key small pelagic fish sustaining Mediterranean ecosystems and fisheries. This study represents the first comprehensive biological and population dynamics assessment of the European pilchard by applying the length‐based spawning potential ratio (LB‐SPR) approach to S.
Mohab Badreldin   +3 more
wiley   +1 more source

Heterogeneity of iridoid biosynthesis in catmints: Molecular background in a phylogenetic context

open access: yesJournal of Integrative Plant Biology, EarlyView.
Evolutionary gains and losses of key biosynthetic genes likely resulting from multiple independent evolutionary events explain why certain Nepeta (catnip) species produce both the active, cat‐attracting nepetalactones and sugar‐bound iridoids, while others make only the sugar‐bound forms, and some have lost iridoid production entirely.
Tijana Banjanac   +15 more
wiley   +1 more source

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