Results 71 to 80 of about 142,714 (313)
Journal of Experimental & Clinical Cancer Research, 2018 Background Oncogenic roles of epidermal growth factor receptor pathway substrate no.8 (EPS8) have been widely reported in various tumors, making targeting of EPS8 an appealing prospect.
Yiran Chen +6 more
doaj +1 more source
Advanced Materials, EarlyView.A schematic illustration of how noble metals can be used to create nanoparticles (NPs) or nanoclusters (NCs). Noble metal NPs, due to their plasmonic properties, enable photothermal therapy and surface‐enhanced Raman scattering (SERS). In contrast, NCs, which lack a plasmonic resonance band, exhibit fluorescence, making them ideal for bioimaging ...
David Esporrín‐Ubieto +3 more
wiley +1 more source
Interplay between kinase domain autophosphorylation and F-actin binding domain in regulating imatinib sensitivity and nuclear import of BCR-ABL. [PDF]
PLoS ONE, 2011 The constitutively activated BCR-ABL tyrosine kinase of chronic myeloid leukemia (CML) is localized exclusively to the cytoplasm despite the three nuclear localization signals (NLS) in the ABL portion of this fusion protein.
Martin Preyer +2 more
doaj +1 more source
Nonvanishing boundary conditions and dark solitons in the NLS model
, 2009 We consider non-vanishing boundary conditions (NVBC) for the NLS model [6,7,27] in the context of the hybrid dressing transformation and $\tau$-function approach.
Blas, H. +2 more
core +1 more source
The Morphological, Behavioral, and Transcriptomic Life Cycle of Anthrobots
Advanced Science, EarlyView.DNA is thought to determine shape, behavior, and lifespan, with developmental plasticity reserved for stem cells, embryos, and species like amphibia. How much morphogenetic plasticity do adult somatic human cells exhibit? Anthrobots are a self‐organizing, motile synthetic living construct made of genetically normal human epithelial cells.
Gizem Gumuskaya +6 more
wiley +1 more source
Nuclear Physics B, 2023 The nonlinear Schrödinger (NLS) types of equations play a key role in quantum mechanics, Quantum communication and physical applications. However, how to deal with explicit solutions and other properties of the NLS equations, especially for the variable ...
Hanze Liu
doaj
7 Tesla magnetic resonance imaging to detect cortical pathology in multiple sclerosis. [PDF]
PLoS ONE, 2014 Neocortical lesions (NLs) are an important pathological component of multiple sclerosis (MS), but their visualization by magnetic resonance imaging (MRI) remains challenging.We aimed at assessing the sensitivity of multi echo gradient echo (ME-GRE) T2 ...
Bing Yao +7 more
doaj +1 more source
On nonlinear Schr\"odinger equations with almost periodic initial data [PDF]
, 2015 We consider the Cauchy problem of nonlinear Schr\"odinger equations (NLS) with almost periodic functions as initial data. We first prove that, given a frequency set $\pmb{\omega} =\{\omega_j\}_{j = 1}^\infty$, NLS is local well-posed in the algebra ...
Oh, Tadahiro
core
Time-Reversal Generation of Rogue Waves
, 2014 The formation of extreme localizations in nonlinear dispersive media can be explained and described within the framework of nonlinear evolution equations, such as the nonlinear Schr\"odinger equation (NLS).
Chabchoub, Amin, Fink, Mathias
core +2 more sources
Cryptic Splicing of GAP43 mRNA is a Novel Hallmark of TDP‐43‐Associated ALS and AD
Advanced Science, EarlyView.TDP‐43 dysfunction disrupts RNA processing, inducing cryptic exon 4a1 inclusion in GAP43 and reducing its protein levels. This aberrant splicing impairs axonal regeneration and contributes to neurodegeneration in ALS and AD. RNA‐seq of patient brains reveals GAP43 downregulation and 4a1 upregulation, identifying cryptic exon 4a1 as a potential ...
Mingming Yang +9 more
wiley +1 more source