Results 81 to 90 of about 28,373 (282)
JCPP Advances, EarlyView.Abstract Background Sex differences in the frequency and timing of attention‐deficit/hyperactivity disorder (ADHD) diagnosis exist. While there are multiple known individual and wider consequences for young females with delayed or undiagnosed ADHD, little is known about mental health service utilisation (HSU) impacts.
Estelle Alderson +4 more
wiley +1 more source
In vitro study of aberrant translation termination in the context of NMD-sensitive mRNAs
, 2017 Nonsense-mediated mRNA decay (NMD) is one of the best studied eukaryotic mRNA degradation pathways but the initial steps of its activation in mammalian cells remain unclear.
Karousis, Evangelos
core +1 more source
Can DNA from wet, temperate soils be used for palaeoecological reconstruction?
Journal of Quaternary Science, EarlyView.ABSTRACT Sedimentary ancient DNA in well‐dated contexts (sedaDNA) has great potential as a palaeoecological proxy. A few studies have attempted palaeoecological reconstructions using sedaDNA from soil; these studies have been mainly restricted to cold and/or dry soils.
Nick A. Cutler +3 more
wiley +1 more source
Journal of Quaternary Science, EarlyView.ABSTRACT Subfossil insect communities from the Quartz Creek site provide a detailed record of both Late Pleistocene steppe–tundra and Holocene boreal forest ecosystems in central Yukon Territory, Canada. Fifteen Pleistocene assemblages (marine isotope stages [MIS] 4 to 2) are dominated by steppe–tundra and dry‐tundra taxa, particularly the weevils ...
Scott L. Cocker +4 more
wiley +1 more source
Degradation of Gadd45 mRNA by nonsense-mediated decay is essential for viability
eLife, 2016 The nonsense-mediated mRNA decay (NMD) pathway functions to degrade both abnormal and wild-type mRNAs. NMD is essential for viability in most organisms, but the molecular basis for this requirement is unknown.
Jonathan O Nelson +4 more
doaj +1 more source
myo‐Inositol's role in laying hens’ active gastrointestinal microbiota: a strain comparison
Journal of the Science of Food and Agriculture, EarlyView.Abstract BACKGROUND myo‐Inositol (MI) is a cyclitol involved in cellular metabolism and phytate degradation, yet its influence on the gastrointestinal tract (GIT) microbiota of laying hens remains poorly understood. This study investigated the effects of graded dietary MI supplementation on the active GIT microbial communities of two commercial laying ...
Naomi Sarpong +4 more
wiley +1 more source
RNA virus evasion of nonsense-mediated decay.
PLoS Pathogens, 2018 Nonsense-mediated decay (NMD) is a host RNA control pathway that removes aberrant transcripts with long 3' untranslated regions (UTRs) due to premature termination codons (PTCs) that arise through mutation or defective splicing.
Jared P May +3 more
doaj +1 more source
ICE1 promotes the link between splicing and nonsense-mediated mRNA decay
eLife, 2018 The nonsense-mediated mRNA decay (NMD) pathway detects aberrant transcripts containing premature termination codons (PTCs) and regulates expression of 5–10% of non-aberrant human mRNAs.
Thomas D Baird +6 more
doaj +1 more source
Mechanistic aspects of NMD in human cells
, 2013 Eukaryotic mRNAs with premature translation termination codons (PTCs) are recognized and degraded through a process termed nonsense-mediated mRNA decay (NMD).
Mühlemann, Oliver
core