Results 11 to 20 of about 298,750 (304)

Effect of MK-801 Treatment and Endurance Training on Angiogenic Response in Cardiac Muscle [PDF]

open access: yes운동과학, 2019
PURPOSE The purpose of this study was to investigate the effects of regular endurance exercise on the changes of angiogenic biomarkers in myocardial tissues of the schizophrenia-induced rats. METHODS Twenty-one SD rats were randomly assigned to CON (n=7),
Youngpyo Hong, Hyoseong Yeo
doaj   +1 more source

Новый взгляд на патогенез депрессии: возможно ли появление быстродействующих антидепрессантов?

open access: yesСовременная терапия психических расстройств, 2020
Рекуррентное депрессивное расстройство является одним из самых распространенных и высокозатратных психических заболеваний в мире. На настоящий момент актуальна моноаминовая теория депрессии, однако открытие около 20 лет назад антидепрессивных свойств
Мосолов, С.Н.   +1 more
doaj   +1 more source

Ofatumumab, a fully human anti-CD20 monoclonal antibody, in the treatment of severe refractory Anti-N-methyl-D-aspartate receptor encephalitis: Two case reports

open access: yesAnnals of Indian Academy of Neurology, 2023
Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is a type of autoimmune encephalitis (AE) characterized by antibodies against NMDA receptor. As the most common AE, anti-NMDAR encephalitis affects 54% ~ 80% of patients with AE.
Hongfei Xue   +8 more
doaj   +1 more source

Hydrocarbon molar water solubility predicts NMDA vs. GABAA receptor modulation. [PDF]

open access: yes, 2014
BackgroundMany anesthetics modulate 3-transmembrane (such as NMDA) and 4-transmembrane (such as GABAA) receptors. Clinical and experimental anesthetics exhibiting receptor family specificity often have low water solubility. We hypothesized that the molar
Brosnan, Robert J, Pham, Trung L
core   +2 more sources

Brain NMDA Receptors in Schizophrenia and Depression

open access: yesBiomolecules, 2020
N-methyl-D-aspartate (NMDA) receptor antagonists such as phencyclidine (PCP), dizocilpine (MK-801) and ketamine have long been considered a model of schizophrenia, both in animals and humans.
A. Adell
semanticscholar   +1 more source

Inhibition of Food Intake by PACAP in the Hypothalamic Ventromedial Nuclei is Mediated by NMDA Receptors [PDF]

open access: yes, 2014
Central injections of pituitary adenylate cyclase-activating polypeptide (PACAP) into the ventromedial nuclei (VMN) of the hypothalamus produce hypophagia that is dependent upon the PAC1 receptor; however, the signaling downstream of this receptor in the
Choi, Sujean   +3 more
core   +2 more sources

Intrinsic up-regulation of 2-AG favors an area specific neuronal survival in different in vitro models of neuronal damage [PDF]

open access: yes, 2012
BACKGROUND: The endocannabinoid 2-arachidonoyl glycerol (2-AG) acts as a retrograde messenger and modulates synaptic signaling e. g. in the hippocampus. 2-AG also exerts neuroprotective effects under pathological situations.
Bechmann, Ingo Jürgen   +8 more
core   +8 more sources

Berberis vulgaris extract-based Fe3O4 nanocomposites affect NMDA1 function and physical activity: Analysis of Grin1 expression in Syrian mice model of Experimental autoimmune encephalomyelitis [PDF]

open access: yesAdvanced Herbal Medicine, 2021
Background: Ionotropic glutamate NMDA receptors are multi-subunit proteins with few selective pharmacological ligands and are tentatively implicated in MS and other neurodegenerative disorders.
Fatemeh Noruzifard   +2 more
doaj  

Establishment of an adult zebrafish model of retinal neurodegeneration induced by NMDA [PDF]

open access: yesInternational Journal of Ophthalmology, 2019
AIM: To establish a model of retinal neurodegeneration induced by N-Methyl-D-aspartic acid (NMDA) in adult zebrafish. METHODS: We compared the effects of three different NMDA delivery methods on retinal neurodegeneration in adult zebrafish: immersion (I.
Zhi-Wen Luo   +10 more
doaj   +1 more source

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