Effect of MK-801 Treatment and Endurance Training on Angiogenic Response in Cardiac Muscle [PDF]
PURPOSE The purpose of this study was to investigate the effects of regular endurance exercise on the changes of angiogenic biomarkers in myocardial tissues of the schizophrenia-induced rats. METHODS Twenty-one SD rats were randomly assigned to CON (n=7),
Youngpyo Hong, Hyoseong Yeo
doaj +1 more source
Новый взгляд на патогенез депрессии: возможно ли появление быстродействующих антидепрессантов?
Рекуррентное депрессивное расстройство является одним из самых распространенных и высокозатратных психических заболеваний в мире. На настоящий момент актуальна моноаминовая теория депрессии, однако открытие около 20 лет назад антидепрессивных свойств
Мосолов, С.Н. +1 more
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Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is a type of autoimmune encephalitis (AE) characterized by antibodies against NMDA receptor. As the most common AE, anti-NMDAR encephalitis affects 54% ~ 80% of patients with AE.
Hongfei Xue +8 more
doaj +1 more source
Crystal structure of a heterotetrameric NMDA receptor ion channel
Erkan Karakas, Hiro Furukawa
exaly +2 more sources
Hydrocarbon molar water solubility predicts NMDA vs. GABAA receptor modulation. [PDF]
BackgroundMany anesthetics modulate 3-transmembrane (such as NMDA) and 4-transmembrane (such as GABAA) receptors. Clinical and experimental anesthetics exhibiting receptor family specificity often have low water solubility. We hypothesized that the molar
Brosnan, Robert J, Pham, Trung L
core +2 more sources
Brain NMDA Receptors in Schizophrenia and Depression
N-methyl-D-aspartate (NMDA) receptor antagonists such as phencyclidine (PCP), dizocilpine (MK-801) and ketamine have long been considered a model of schizophrenia, both in animals and humans.
A. Adell
semanticscholar +1 more source
Inhibition of Food Intake by PACAP in the Hypothalamic Ventromedial Nuclei is Mediated by NMDA Receptors [PDF]
Central injections of pituitary adenylate cyclase-activating polypeptide (PACAP) into the ventromedial nuclei (VMN) of the hypothalamus produce hypophagia that is dependent upon the PAC1 receptor; however, the signaling downstream of this receptor in the
Choi, Sujean +3 more
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Intrinsic up-regulation of 2-AG favors an area specific neuronal survival in different in vitro models of neuronal damage [PDF]
BACKGROUND: The endocannabinoid 2-arachidonoyl glycerol (2-AG) acts as a retrograde messenger and modulates synaptic signaling e. g. in the hippocampus. 2-AG also exerts neuroprotective effects under pathological situations.
Bechmann, Ingo Jürgen +8 more
core +8 more sources
Berberis vulgaris extract-based Fe3O4 nanocomposites affect NMDA1 function and physical activity: Analysis of Grin1 expression in Syrian mice model of Experimental autoimmune encephalomyelitis [PDF]
Background: Ionotropic glutamate NMDA receptors are multi-subunit proteins with few selective pharmacological ligands and are tentatively implicated in MS and other neurodegenerative disorders.
Fatemeh Noruzifard +2 more
doaj
Establishment of an adult zebrafish model of retinal neurodegeneration induced by NMDA [PDF]
AIM: To establish a model of retinal neurodegeneration induced by N-Methyl-D-aspartic acid (NMDA) in adult zebrafish. METHODS: We compared the effects of three different NMDA delivery methods on retinal neurodegeneration in adult zebrafish: immersion (I.
Zhi-Wen Luo +10 more
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