Results 331 to 340 of about 240,251 (364)
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Anoxia and NMDA Receptors

1990
Brief periods of anoxia cause a marked, but apparently fully reversible interruption of integrated brain function, whose cellular mechanism is not yet fully understood. For some 50 years it has been known that the hippocampus is one of the first brain regions to be affected by anoxia (Sugar and Gerard 1937).
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Astrocytic NMDA Receptors

Biochemistry (Moscow)
Astrocytic NMDA receptors (NMDARs) are heterotetramers, whose expression and properties are largely determined by their subunit composition. Astrocytic NMDARs are characterized by a low sensitivity to magnesium ions and low calcium conductivity. Their activation plays an important role in the regulation of various intracellular processes, such as gene ...
Artem M, Kosenkov   +2 more
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Neuroprotection by both NMDA and non-NMDA receptor antagonists in in vitro ischemia

Brain Research, 1997
We have investigated the relative contributions of oxygen and glucose deprivation to ischaemic neurodegeneration in organotypic hippocampal slice cultures. Cultures prepared from 10-day-old rats were maintained in vitro for 14 days and then deprived of either oxygen (hypoxia), glucose (hypoglycaemia), or both oxygen and glucose (ischaemia).
Pringle, A.K.   +5 more
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NMDA RECEPTORS IN ALCOHOLISM

2003
Abstract Alcohol dependence (“alcoholism”) is diagnosed based in part on the development of physiological adaptations to alcohol (ethanol) including tolerance and dependence, and loss of control over alcohol intake. It is believed that alcohol is initially ingested for its reinforcing effects (positive or negative), and that adaptive changes in the ...
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Determination of NMDA NR1 subunit copy number in recombinant NMDA receptors

Proceedings of the Royal Society of London. Series B: Biological Sciences, 1995
Co-expression of wild-type and mutated NMDA NR1 (N598R) subunits in Xenopus oocytes has been used to determine the stoichiometry of the NMDA receptor-channel. When expressed together, wild-type NR2A and mutant NR1 (N598R) subunits produced channels with a main conductance of 2.6 pS and a sublevel of 1.2 pS.
Philippe Behe   +5 more
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NMDA AND NON-NMDA RECEPTOR MEDIATED SYNAPSES IN CORTEX

Clinical Neuropharmacology, 1992
David C. West, Alex M. Thomson
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Structural basis of ketamine action on human NMDA receptors

Nature, 2021
Youyi Zhang, Fei Ye, Tongtong Zhang
exaly  

The NMDA receptor

Journal of the Neurological Sciences, 1990
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