Results 161 to 170 of about 197,779 (358)
The contributions of NMDA, non-NMDA, and GABA receptors to postsynaptic responses in neurons of the optic tectum [PDF]
PW Hickmott, Martha Constantine‐Paton
openalex +1 more source
Analgesia for Thoracic Surgery: Does Intraoperative Methadone Deserve a Place?
Intraoperative methadone: potential benefits and considerations for thoracic surgery analgesia.
Eugene Constantine Lai+5 more
wiley +1 more source
The Effects of Serotonin on Functionally Diverse Isolated Lamprey Spinal Cord Neurons [PDF]
The experiments reported here showed that application of serotonin (5-hydroxytryptamine, 5-HT) (100 µ M) did not induce any significant current through the membranes of any of the spinal neurons studied (n = 62).
Batueva, I. V.+4 more
core +1 more source
The effect of centrally acting myorelaxants on NMDA receptor‐mediated synaptic transmission in the immature rat spinal cord in vitro [PDF]
Richard J. Siarey+2 more
openalex +1 more source
Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs+12 more
wiley +1 more source
Preclinical models for evaluating psychedelics in the treatment of major depressive disorder
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander+5 more
wiley +1 more source
Psychedelics, entactogens and psychoplastogens for depression and related disorders
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley +1 more source
Abstract Background and purpose Clozapine, an approved antipsychotic for treatment‐resistant schizophrenia (TRS), enhances glutamatergic transmission by increasing exocytosis and non‐exocytosis glutamate release; however, its full action remained to be clarified.
Motohiro Okada+2 more
wiley +1 more source