Results 171 to 180 of about 203,682 (360)

Negative allosteric modulators of the GluN2B NMDA receptor with phenylethylamine structure embedded in ring-expanded and ring-contracted scaffolds

, 2020
Louisa Temme, Elena Bechthold, Julian A. Schreiber, Sandeep Gawaskar, Dirk Schepmann, Dina Robaa, Wolfgang Sippl, Guiscard Seebohm, Bernhard Wünsch   +8 more
openalex   +1 more source

The DREAM Protein Negatively Regulates the NMDA Receptor through Interaction with the NR1 Subunit [PDF]

, 2010
Ying Zhang, Ping Su, Ping Liang, Tao Liu, Xu Liu, Xin Ying Liu, Bo Zhang, Tao Han, Yan-Bing Zhu, Dong‐Min Yin, Junfa Li, Zhuan Zhou, Ke-Wei Wang, Yun Wang   +13 more
openalex   +1 more source

Efficient analysis of toxicity and mechanisms of isoflurane on postoperative delirium by network toxicology and molecular docking

Neuroprotection, EarlyView.
Abstract Postoperative delirium (POD), a prevalent neurological complication in older surgical patients, adversely affects recovery. Isoflurane, a common inhalational anesthetic, exhibits neurotoxic potential, but its role in POD pathogenesis remains unclear.
Zhiming Dai, Qing Nan, Menglu Xu, Hongbao Li   +3 more
wiley   +1 more source

Dopamine is not Required for the Hyperlocomotor Response to NMDA Receptor Antagonists [PDF]

, 2005
Elena H. Chartoff, Carrie Heusner, Richard D. Palmiter   +2 more
openalex   +1 more source

Exploiting glial cell functions for neurodegeneration therapy

Neuroprotection, EarlyView.
The figure illustrates the potential of targeting glial cell functions and their interactions with neurons as a therapeutic strategy for neurodegeneration. Abstract Glial cells, alongside neurons, are the major cells of the central nervous system.
Tobiloba S. Olajide
wiley   +1 more source

Are physiological oscillations physiological?

The Journal of Physiology, EarlyView., 2023
Abstract figure legend Mechanisms and functions of physiological oscillations. Abstract Despite widespread and striking examples of physiological oscillations, their functional role is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen questions about its oscillatory function.
Lingyun (Ivy) Xiong, Alan Garfinkel
wiley   +1 more source

Subunit Arrangement in N-Methyl-d-aspartate (NMDA) Receptors [PDF]

, 2010
Anu Rambhadran, Jennifer M. Reingle González, Vasanthi Jayaraman   +2 more
openalex   +1 more source

Leukoencephalopathy, a Frequent Complication After High‐Dose Methotrexate in Treatment of Osteosarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Methotrexate‐associated leukoencephalopathy is poorly documented in osteosarcoma. Since 2007, our institution has monitored osteosarcoma patients with sequential magnetic resonance imaging (MRI) and neuropsychological evaluations during treatment and follow‐up.
Sandra Raimbault, Jean Louis Amegnizin, Audrey Longaud, Brice Fresneau, Nathalie Gaspar, Pablo Berlanga, Virginie Kieffer, Anne Maraval, Lucy Metayer, Christelle Dufour, Dominique Valteau‐Couanet, Pierre Brugieres, Blanche Bapst, Laurence Brugieres   +13 more
wiley   +1 more source

Failures and successes of NMDA receptor antagonists: Molecular basis for the use of open-channel blockers like memantine in the treatment of acute and chronic neurologic insults [PDF]

, 2004
Stuart A. Lipton
openalex   +1 more source

Photopharmacology beyond azobenzene photoswitches

Responsive Materials, EarlyView.
Photopharmacology is advancing beyond traditional azobenzene photoswitches by developing new photoresponsive molecules with improved thermal stability, efficiency, and long‐wavelength activation, enhancing their potential for precise biomedical applications.
Huichao Guo, Jinghong Dai, Long Deng, Zhiwei Zhang, He Tian, Junji Zhang   +5 more
wiley   +1 more source