Results 221 to 230 of about 186,082 (377)

Toward molecular phenotyping of temporal lobe epilepsy by spatial omics

Epilepsia, EarlyView.
Abstract Objective In temporal lobe epilepsy (TLE), detection of the epileptogenic zone predicts a good surgical outcome. When submitted to 18F‐fluorodeoxyglucose positron emission tomography (PET), some patients display lateralized, focal hypometabolism in the temporal lobe (PET+), whereas others appear normometabolic (PET−).
Isabeau Vermeulen, Ronny Mohren, Micca Neusinger, Tobias A. Dancker, Michiel Vandenbosch, Jan Beckervordersandforth, Benjamin Balluff, Rianna P. Van der Hel, Olaf E. M. G. Schijns, Govert Hoogland, Kim Rijkers, Berta Cillero‐Pastor, ACE epilepsy surgery group, Gwendolyn de Bruyn, Albert Colon, Jim Dings, Marc Hendriks, Danny Hilkman, Christianne Hoeberigs, Jochem van der Pol, Lotte de Jong, Kim Rijkers, Sylvia Klinkenberg, Vivianne van Kranen–Mastenbroek, Jeske Nelissen, Pieter Kubben, Walter M. Palm, Rob P. W. Rouhl, Olaf Schijns, Ilse van Straaten, Simon Tousseyn, Marielle Vlooswijk, Louis Wagner, Dorien Weckhuysen   +33 more
wiley   +1 more source

NMDA Receptor-Mediated Ca²⁺ Flux Attenuated by the NMDA Receptor/TRPM4 Interface Inhibitor Brophenexin. [PDF]

Pharmacol Res Perspect
Casby J, Gansemer BM, Thayer SA.
europepmc   +1 more source

Structures of the M2 channel-lining segments from nicotinic acetylcholine and NMDA receptors by NMR spectroscopy. [PDF]

, 1999
Stanley J. Opella, Francesca M. Marassi, Jennifer J. Gesell, Ana Paula Valente, Y. Kim, M. Oblatt-Montal, M Montal   +6 more
openalex   +1 more source

Sustained rescue of seizure control in patients with highly refractory chronic epilepsy using empiric immunotherapy

Epilepsia, EarlyView.
Abstract Objective Following emerging evidence of autoimmune‐associated seizures in medication‐refractory epilepsy, we began offering a trial of immunotherapy to selected patients. Here, we review this approach's treatment response, predictive clinical features, and utility.
Elisabeth Doran, Albert Kelly, Raluca Stanila, Laura Healy, Colin P. Doherty   +4 more
wiley   +1 more source

Regulation of Synaptic NMDA Receptor Activity by Post-Translational Modifications. [PDF]

Neurochem Res
Tahiri E, Corti E, Duarte CB.
europepmc   +1 more source

The Effects of NMDA Receptor Antagonists and Nitric Oxide Synthase Inhibitors on Opioid Tolerance and Withdrawal Medication Development Issues for Opiate Addiction [PDF]

, 1995
Barry K. Herman
openalex   +1 more source

Metabolomic and proteomic stratification of equine osteoarthritis

Equine Veterinary Journal, EarlyView.
Abstract Background Equine osteoarthritis (OA) is predominantly diagnosed through clinical examination and radiography, leading to detection only after significant joint pathology. The pathogenesis of OA remains unclear and while many medications modify the disease's inflammatory components, no curative or reversal treatments exist.
James R. Anderson, Marie M. Phelan, Eva Caamaño‐Gutiérrez, Peter D. Clegg, Luis M. Rubio‐Martinez, Mandy J. Peffers   +5 more
wiley   +1 more source

Bridging the gap: insights into sensorimotor deficits in NMDA receptor antibody encephalitis. [PDF]

J Clin Invest
Opal P, Swanson GT.
europepmc   +1 more source

Brain spectrin binding to the NMDA receptor is regulated by phosphorylation, calcium and calmodulin [PDF]

, 1998
Aharon Wechsler, Vivian I. Teichberg
openalex   +1 more source

The universal role of adaptive transcription in health and disease

The FEBS Journal, EarlyView.
Adaptive transcription via molecules such as CREB, MEF2, SRF, AP1, Nr4a1, and Egr1 constitutes a universal mechanism for directed cell state transitions in health and disease. These molecules are involved in physiological adaptation processes, pathological maladaptations, curative adaptations, and development of resistance to treatment.
Thomas Lissek
wiley   +1 more source