Results 231 to 240 of about 2,517,861 (360)

NMDA receptor subunits: function and pharmacology.

open access: yesCurrent opinion in pharmacology (Print), 2007
P. Paoletti, J. Neyton
semanticscholar   +1 more source

Myeloid PD‐1 Regulates Astrocyte Development and Leads to Active Behaviours

open access: yesCell Proliferation, EarlyView.
During early neurodevelopment, PD‐1 ablation in myeloid cells influences myeloid proliferation/differentiation and causes sustained astrocyte overproliferation. PD‐1f/f; LysM‐Cre mice showed elevated astrocyte gene expression and behavioural changes.
Jie Qin   +6 more
wiley   +1 more source

Enhancement of hippocampal interneuron excitability by NMDA receptor positive allosteric modulation. [PDF]

open access: yesJ Physiol
Xing H   +14 more
europepmc   +1 more source

Spreading depolarization and its influence on epileptiform activity

open access: yesEpilepsia, EarlyView.
Abstract Spreading depolarization (SD) is a transient disruption of electrographic activity that slowly propagates through the gray matter by chemical contiguity, and it is characterized by a large depolarization of neurons and glial cells. SD, which is associated with massive changes in ion homeostasis, including extreme increases in [K+]o, was shown ...
Maxime Lévesque   +2 more
wiley   +1 more source

Cryo-EM snapshots of NMDA receptor activation illuminate sequential rearrangements. [PDF]

open access: yesSci Adv
Abbott JA   +5 more
europepmc   +1 more source

Interleukin-1β Enhances NMDA Receptor-Mediated Intracellular Calcium Increase through Activation of the Src Family of Kinases

open access: yesJournal of Neuroscience, 2003
B. Viviani   +10 more
semanticscholar   +1 more source

Neuronal hyperexcitability: A key to unraveling hippocampal synaptic dysfunction in Lafora disease

open access: yesEpilepsia, EarlyView.
Abstract Background and Objective Lafora disease (LD) is a rare progressive disorder caused by mutations in the EPM2A or EPM2B genes, characterized by the accumulation of Lafora bodies, drug‐resistant epilepsy, and cognitive decline. To investigate the early molecular mechanisms of LD, we studied electrophysiological changes in the dentate gyrus (DG ...
Cinzia Costa   +17 more
wiley   +1 more source

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