Results 81 to 90 of about 114,424 (204)

Psychiatric presentation of anti-NMDA receptor encephalitis

, 2019
Background: Anti-N-methyl D-aspartate (NMDA) receptor encephalitis is an autoimmune condition characterized by neuropsychiatric symptoms, including epileptic seizures, movement disorders, autonomic instability, disturbances of consciousness, paranoia ...
Rauer, Sebastian, Domschke, Katharina, Feige, Bernd, Heidt, Timo, Prüss, Harald, Egger, Karl, Nickel, Kathrin, Endres, Dominique, Runge, Kimon, Venhoff, Nils, Süß, Patrick, Meyer, Philipp T., Maier, Simon J., Tebartz van Elst, Ludger, Kern, Winfried   +14 more
core   +1 more source

NMDA Receptor Antagonists: Emerging Insights into Molecular Mechanisms and Clinical Applications in Neurological Disorders

Pharmaceuticals
Neurodegenerative disorders (NDs) include a range of chronic conditions characterized by progressive neuronal loss, leading to cognitive, motor, and behavioral impairments.
Ayodeji Olatunde Egunlusi, Jacques Joubert   +1 more
doaj   +1 more source

Diabetic retinopathy and the NMDA receptor [PDF]

Drug News & Perspectives, 2002
Diabetic retinopathy is a major sight-threatening disease and is a leading cause of blindness. There is an emerging body of evidence that suggests that neuronal changes are an early phenomenon in the diabetic retina and that several cell types are affected, including the ganglion cells.
openaire   +2 more sources

Tau is required for the function of extrasynaptic NMDA receptors

Scientific Reports, 2019
Tau is a microtubule-associated neuronal protein found mainly in axons. However, increasing evidence indicates that it is also present in dendrites, where it serves as an essential mediator of synaptic NMDA (N-methyl-D-aspartate) receptor-dependent ...
Noemí Pallas-Bazarra, Jonathan Draffin, Raquel Cuadros, José Antonio Esteban, Jesús Avila   +4 more
doaj   +1 more source

Schematic representation of memantine and NMDA receptor.

, 2013
Schematic representation of memantine and NMDA receptor.
W. Ted Brown (167450), Xiaohong Li (71964), Hongen Wei (323077), Mazhar Malik (323081), Ashfaq M. Sheikh (323080), Carl Dobkin (323079)   +5 more
core   +1 more source

MODULATION OF NMDA RECEPTOR-MEDIATED SYNAPTIC TRANSMISSION

, 2017
NMDA receptors are ligand-gated ion channels with unique features that make them central to critical processes in the central nervous system. Neural circuits have a remarkable ability to modulate NMDA receptor activation to communicate vast amounts of ...
Lind, Genevieve Elysian
core  

The Clinical Significance of Abnormal Electroencephalography (EEG) Patterns in Patients with Neuropsychiatric Disorders Due to Anti-NMDA Receptor Encephalitis: A Comparative Study

Diagnostics
Background: Anti-NMDA receptor encephalitis is an autoimmune disease characterized by severe neuropsychiatric disturbances, often misdiagnosed as a primary psychiatric disorder.
Alvaro Moreno-Avellán, Arely Juarez-Jaramillo, Maria del Carmen Fernandez Gonzalez-Aragon, Gerardo Quiñones-Pesqueira, Luz Maria Pineda-Centeno, Mariana Espinola-Nadurille, Victoria Martinez-Angeles, Francisco Martinez-Carrillo, Veronica Rivas-Alonso, Daniel San-Juan, Jose Flores-Rivera, Jesus Ramirez-Bermudez   +11 more
doaj   +1 more source

Subtype-Specific Agonists for NMDA Receptor Glycine Binding Sites

, 2017
A series of analogues based on serine as lead structure were designed, and their agonist activities were evaluated at recombinant NMDA receptor subtypes (GluN1/2A-D) using two-electrode voltage-clamp (TEVC) electrophysiology.
Kasper B. Hansen, Alex R. Maolanon, Risgaard, Rune, Rasmus P. Clausen, Papangelis, Athanasios, Athanasios Papangelis, David Holley, Yi, Feng, Svenstrup, Niels, Barslund, Anne F., Feng Yi, Hansen, Kasper B., Snoep, Yoran, Holley, David, Rune Risgaard, Yoran Snoep, Wang, Shuang Yan, Clausen, Rasmus P., Shuang-Yan Wang, Anne F. Barslund, Maolanon, Alex R., Niels Svenstrup   +21 more
core   +1 more source

NMDA receptor mediated regulation of human megakaryocytopoiesis

, 2003
Identification of the regulatory inputs that direct megakaryocytopoiesis and platelet production is essential for the development of novel therapeutic strategies for the treatment of thrombosis and related hematologic disorders.
Skerry, T.M., Hitchcock, I.S., Howard, M.R., Genever, P.G.   +3 more
core   +1 more source

The behavioral effects of NMDA receptor antagonists [PDF]

, 2011
NMDA (N-methyl-D-aspartate) receptors are glutamate-gated ion channels, which are located in the central nervous system. They permit excitatory neurotransmission and are crucial for synaptic plasticity and other functions, but on the other hand for ...
Chvojková, Markéta
core