Results 61 to 70 of about 114,424 (204)

Coupling of the NMDA receptor to neuroprotective and neurodestructive events [PDF]

, 2009
NMDA (N-methyl-D-aspartate) receptors are a subtype of ionotropic glutamate receptor with an important role in the physiology and pathophysiology of central neurons. inappropriate levels of Ca2+ influx through the NMDA receptor can contribute to neuronal
Hardingham, G. E., Giles E. Hardingham
core   +1 more source

Anti-NMDA Receptor Encephalitis: A Narrative Review. [PDF]

Brain Sci
Antibodies against the NR1 or NR2 subunits of the NMDA receptor are linked to anti-N-methyl-D-aspartate (NMDA) receptor encephalitis, a type of encephalitis that mainly affects women. Clinicians who treat patients of all ages should be aware of this type
Pădureanu V, Dop D, Pădureanu R, Pîrșcoveanu DFV, Olaru G, Streata I, Bugă AM.   +6 more
europepmc   +2 more sources

Fabrication and use of D-serine biosensors for characterising D-serine signalling in rat brain [PDF]

D-serine is a co-agonist at NMDA receptors in the brain but the study of this amino acid is restricted by current techniques. I have designed highly sensitive D-serine biosensors that permit accurate real-time recordings of D-serine in the brain in a ...
Bibi, Shakila
core  

The effect of N-acetyl-aspartyl-glutamate and N-acetyl-aspartate on white matter oligodendrocytes

, 2009
Elevations of the levels of N-acetyl-aspartyl-glutamate (NAAG) and N-acetyl-aspartate (NAA) are associated with myelin loss in the leucodystrophies Canavan's disease and Pelizaeus-Merzbacher-like disease. NAAG and NAA can activate and antagonize neuronal
Attwell, D., Koodziejczyk, Karolina, Kolodziejczyk, K., Wade, A., Kradttir, Ragnhildur, Wade, Anna, Karadottir, R., Hamilton, Nicola B.; id_orcid, Attwell, David, Hamilton, N. B.   +9 more
core   +1 more source

New-Onset Headache in Patients With Autoimmune Encephalitis Is Associated With anti-NMDA-Receptor Antibodies.

, 2016
OBJECTIVE We tested the hypotheses (i) that autoimmune encephalitis is associated with new-onset headache, and (ii) that the occurrence of headache is associated with the presence of anti-N-methyl-D-aspartate (NMDA)-receptor antibodies. BACKGROUND
Straube, Andreas, Csanadi, Endy, Paulus, Walter J., Pellkofer, Hannah L., Pellkofer, Hannah, Kümpfel, Tania, Schankin, Christoph, Paulus, Walter, Winkler, Tobias, Hoegen, Tobias, Kuempfel, Tania, Kästele, Fabian, Kaestele, Fabian, Högen, Tobias, Schankin, Christoph J., Gerdes, Lisa Ann   +15 more
core   +1 more source

Action of GABAB receptor on local network oscillation in somatosensory cortex of oral part: focusing on NMDA receptor

Journal of Physiological Sciences
The balance of activity between glutamatergic and GABAergic networks is particularly important for oscillatory neural activities in the brain. Here, we investigated the roles of GABAB receptors in network oscillation in the oral somatosensory cortex (OSC)
Hiroyuki Kanayama, Takashi Tominaga, Yoko Tominaga, Nobuo Kato, Hiroshi Yoshimura   +4 more
doaj   +1 more source

Homocysteic acid and the potential role of N-methyl-D-aspartate receptors in cosmetic dermatology: a review

Journal of Cosmetic Medicine
Recent advances in neurocutaneous research have revealed that N-methyl-D-aspartate (NMDA) receptors, which are traditionally associated with neural signaling, play significant roles in skin physiology.
JinHan Lee, Junhwan Jung, Hyungin Cho, Ingyu Lee   +3 more
doaj   +1 more source

Conserved contributions of NMDA receptor subtypes to synaptic responses in lamina II spinal neurons across early postnatal development

Molecular Brain, 2020
NMDA receptors are heteromeric complexes that contribute to excitatory synaptic transmission and plasticity. The presence of specific variants of GluN2 subunits in these complexes enables diversity in NMDA receptor function and regulation.
Hadir Mahmoud, Newton Martin, Michael E. Hildebrand   +2 more
doaj   +1 more source

Slow in Motion but Smart in Learning and Memory: Behavioral Changes in Adult NR3A Knockout Mice

, 2011
The expression of NMDA receptor subunit NR3A is high in the neonatal brain but low in adults. However, its functional role in the adult brain is obscure.
Shan Ping Yu, Ling Wei, Osama Mohamad, Mingke Song   +3 more
core   +1 more source

Selective vulnerabilities of N-methyl-D-aspartate (NMDA) receptors during brain aging

Frontiers in Aging Neuroscience, 2010
N-methyl-D-aspartate (NMDA) receptors are present in high density within the cerebral cortex and hippocampus and play an important role in learning and memory.
Brenna L Brim, Siba R Das
doaj   +1 more source