Estudo do papel do receptor gabaB na aquisição da tolerancia rapida ao etanol em camundongos submetidos ao teste do rota-rod [PDF]
, 1998 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciencias BiologicasAnálise da influência do receptor GABAB no desenvolvimento da tolerância rápida ao etanol em camundongos, no teste do rota-rod.
Zaleski, Marcos Jose Barreto
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NMDAR‐antibody encephalitis: Seizure semiology and EEG findings
Epileptic Disorders, EarlyView.Abstract Background N‐methyl‐D‐aspartate receptor antibody encephalitis (NMDAR‐Ab‐E) is an autoantibody‐mediated disorder, characterized by acute development of neuropsychiatric symptoms, seizures, movement disorders, and autonomic instability. Objectives To describe acute seizure semiology and electroencephalogram (EEG) findings in patients with a ...
Maria Emilia C. Andraus +6 more
wiley +1 more source
Fabrication and use of D-serine biosensors for characterising D-serine signalling in rat brain [PDF]
D-serine is a co-agonist at NMDA receptors in the brain but the study of this amino acid is restricted by current techniques. I have designed highly sensitive D-serine biosensors that permit accurate real-time recordings of D-serine in the brain in a ...
Bibi, Shakila
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Slow in Motion but Smart in Learning and Memory: Behavioral Changes in Adult NR3A Knockout Mice [PDF]
, 2011 The expression of NMDA receptor subunit NR3A is high in the neonatal brain but low in adults. However, its functional role in the adult brain is obscure.
Shan Ping Yu +3 more
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Envolvimento dos receptores NMDA e da via L-arginina-óxido nítrico-GMPc no efeito tipo-antidepressivo da guanosina [PDF]
, 2012 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em Neurociências.A guanosina é um nucleosídeo endógeno que modula a captação de glutamato pelos astrócitos, controlando os níveis ...
Bettio, Luis Eduardo Beltrão
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Epilepsia, EarlyView.Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer +7 more
wiley +1 more source
Heliyon, 2018 Neuronal excitotoxicity induced by spreading depolarization occurs during multiple brain diseases. The subsequent extensive releasing of neuronal transmitter glutamate results in over activation of the ionic glutamate receptors and then triggers neuronal
Jia Zhu +5 more
doaj +1 more source
Estudo das Vias de Sinalização Envolvidas no Pré-condicionamento com N-Metil-D-Aspartato (NMDA) sobre Convulsões Induzidas por Ácido Quinolínico em Camundongos [PDF]
, 2008 TCC(graduação) - Universidade Federal de Santa Catarina. Centro de Ciências Biológicas. Biologia.O pré-condicionamento cerebral se refere a um estado de tolerância transitória do tecido nervoso a um estimulo letal evocado por um insulto moderado prévio ...
Herculano, Bruno
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Epilepsia, EarlyView.Abstract Objective In status epilepticus there are concerns that the prolonged high‐intensity electrographic seizure activity causes neuronal death and poorer outcomes. In animal models of status epilepticus, early treatment that stops the seizures prevents the later development of epilepsy.
Yue Chen +2 more
wiley +1 more source
Subchronic memantine induced concurrent functional disconnectivity and altered ultra-structural tissue integrity in the rodent brain: revealed by multimodal MRI [PDF]
, 2013 Background An effective NMDA antagonist imaging model may find key utility in advancing schizophrenia drug discovery research. We investigated effects of subchronic treatment with the NMDA antagonist memantine by using behavioural observation and ...
Ver Donck, L. +29 more
core +1 more source