Dual Palmitoylation of NR2 Subunits Regulates NMDA Receptor Trafficking
, 2009 SummaryModification of NMDA receptor function and trafficking contributes to the regulation of synaptic transmission and is important for several forms of synaptic plasticity.
Richard L. Huganir +5 more
core +1 more source
NMDA receptor blockade attenuates Japanese encephalitis virus infection-induced microglia activation
Journal of NeuroinflammationNeurodegeneration and neuroinflammation are key components in the pathogenesis of Japanese Encephalitis caused by Japanese Encephalitis Virus (JEV) infection.
Cheng-Yi Chang +8 more
doaj +1 more source
Heterocyclic modulators of the NMDA Receptor
, 1993 The design of new heterocyclic derivatives as modulatory agents at EAA receptors is described. In particular, the potent and selective activity at the NMDA receptor of trans-4-hydroxypipecolic acid-4-sulfate, as well as the neuroprotective properties of ...
R. Luneia +9 more
core
VZV brainstem encephalitis triggers NMDA receptor immunoreaction
, 2014 Schäbitz W-R, Rogalewski A, Hagemeister C, Bien C. VZV brainstem encephalitis triggers NMDA receptor immunoreaction. Neurology.
Rogalewski, Andreas ; https://orcid.org/ +3 more
core +1 more source
Molecular pharmacology of a Novel NR2B-selective NMDA Receptor Antagonist [PDF]
, 2006 The NMDA receptor is a heteromeric ligand-gated ion channel in the central nervous system (CNS). There are three families of NMDA receptor subunits with various combinations of NRl, NR2A-D and NR3A֊B subunits producing unique receptors with distinctive ...
Bradford, Andrea Marie
core
Scientific ReportsThe NEGR1 gene has been implicated in several psychiatric disorders, and increased NMDA receptor binding density has been demonstrated in vitro in hippocampal slices from Negr1-deficient mice. In this study, we expanded on these findings by investigating
Carolin Kuuskmäe +9 more
doaj +1 more source
Consequences of NMDA Receptor Disruption for Prefrontal Cortical Neurophysiology
, 2018 Cognitive deficits, indicative of prefrontal cortical disruption, are observed in several neurodevelopmental disorders. Converging evidence suggests these cognitive symptoms arise from abnormalities in N-methyl-D-aspartate (NMDA) receptor function ...
Binko, Mary Ann
core +2 more sources
Molecular Pathways Responsible for NMDA Receptor-mediated Behavioural Plasticity
, 2017 Neurodevelopmental disorders occur from genetic and environmental risk factors that impair the formation of networks involved in learning and memory. Impaired NMDA receptor signaling has been implicated in the pathobiology of schizophrenia and autism.
Islam, Rehnuma
core +2 more sources
Modulation of NMDA Receptor and TRPM4 Activity in Hippocampal Neurons with the NMDA Receptor/TRPM4 Interface Inhibitor Brophenexin. [PDF]
Neurotox ResCasby J +3 more
europepmc +1 more source
Regulation of NMDA receptor interactions with the actin cytoskeleton in dendritic spine development. [PDF]
Front Cell NeurosciLloyd J, Litwa K.
europepmc +1 more source