Results 11 to 20 of about 379,496 (282)

Особливості змісту права громадян на екологічну безпеку [PDF]

, 2009
В статье сделан анализ содержания права граждан на экологическую безопасность, определяется момент, с которого право на экологическую безопасность считается ...
Augustyniak, W., Boelens, R., NMR Spectroscopy, Reetz, M.T., Sub NMR Spectroscopy, Wienk, H.L.J.   +5 more
core   +3 more sources

In-cell NMR characterization of the secondary structure populations of a disordered conformation of α-Synuclein within E. coli cells [PDF]

, 2013
α-Synuclein is a small protein strongly implicated in the pathogenesis of Parkinson’s disease and related neurodegenerative disorders. We report here the use of in-cell NMR spectroscopy to observe directly the structure and dynamics of this protein ...
A Binolfi, Anthony W. P. Fitzpatrick, AS Maltsev, AS Morar, B Fauvet, B Fauvet, BC McNulty, C Camilloni, C Huang, C Lendel, C Li, C Li, CA Waudby, CA Waudby, Carlo Camilloni, Christopher A. Waudby, Christopher M. Dobson, CO Barnes, CR Bodner, CW Bertoncini, D Eliezer, D Sakakibara, DS Biggs, DS Burz, DS Wishart, DS Wishart, E Lescop, EJ De Genst, F Chiti, F Delaglio, F Ferrage, I Bertini, IR Booth, John Christodoulou, JR Allison, K Inomata, KM Slade, KR Metz, Lisa D. Cabrita, Michele Vendruscolo, MM Dedmon, MR Cookson, P Bernadó, P Sarder, P Schanda, PH Weinreb, Piero Andrea Temussi, RC Puetter, SF Gull, T Bartels, TS Ulmer, VN Uversky, VN Uversky, W Wang, WF Vranken, WS Davidson, Z Serber, Z Serber   +57 more
core   +12 more sources

Cys-Ph-TAHA: a lanthanide binding tag for RDC and PCS enhanced protein NMR [PDF]

, 2011
Here we present Cys-Ph-TAHA, a new nonadentate lanthanide tag for the paramagnetic labelling of proteins. The tag can be easily synthesized and is stereochemically homogenous over a wide range of temperatures, yielding NMR spectra with a single set of ...
Peters, Fabian, Maestre-Martinez, M., Leonov, A., Kovacic, L., Becker, S., Boelens, R., Griesinger, C., Cellular Protein Chemistry, NMR Spectroscopy, Sub NMR Spectroscopy   +9 more
core   +2 more sources

Enantiotropy of Simvastatin as a Result of Weakened Interactions in the Crystal Lattice: Entropy-Driven Double Transitions and the Transient Modulated Phase as Seen by Solid-State NMR Spectroscopy

Molecules, 2022
In crystalline molecular solids, in the absence of strong intermolecular interactions, entropy-driven processes play a key role in the formation of dynamically modulated transient phases.
Jiri Brus, Jiri Czernek, Martina Urbanova, Ctirad Červinka   +3 more
doaj   +1 more source

Protein NMR spectroscopy [PDF]

Current Biology, 1998
Protein NMR spectroscopy does have its limitations. It has so far been used mainly for small proteins with molecular weight of less than 30 kDa, although a handful of publications have now reported the NMR study of proteins up to 40–50 kDa. Larger proteins typically have faster relaxation rates, which results in fatter NMR peaks that tend to merge with
openaire   +2 more sources

Ruthenium Olefin Metathesis Catalysts Bearing Carbohydrate-Based N-Heterocyclic Carbenes [PDF]

, 2010
Ru-based olefin metathesis catalysts containing carbohydrate-derived NHCs from glucose and galactose were synthesized and characterized by NMR spectroscopy. 2D-NMR spectroscopy revealed the presence of Ru−C (benzylidene) rotamers at room temperature, and
Grubbs, Robert H., Keitz, Benjamin K.
core   +2 more sources

Energetics of Excitatory and Inhibitory Neurotransmission in Aluminum Chloride Model of Alzheimer’s Disease: Reversal of Behavioral and Metabolic Deficits by Rasa Sindoor

Frontiers in Molecular Neuroscience, 2017
Alzheimer’s disease (AD) is an age-related neurodegenerative disorder, characterized by progressive loss of cognitive functions and memory. Excessive intake of aluminum chloride in drinking water is associated with amyloid plaques and neurofibrillary ...
Kamal Saba, Niharika Rajnala, Pandichelvam Veeraiah, Vivek Tiwari, Rohit K. Rana, Subhash C. Lakhotia, Anant B. Patel   +6 more
doaj   +1 more source

A distinct mechanism of C-type inactivation in the Kv-like KcsA mutant E71V

Nature Communications, 2022
Constriction of the selectivity filter is assumed to be a hallmark of C-type inactivation in K+ channels. Using different high-resolution methods, this study shows a distinct C-type inactivation mechanism in a KcsA mutant that emulates Kv-channels.
Ahmed Rohaim, Bram J. A. Vermeulen, Jing Li, Felix Kümmerer, Federico Napoli, Lydia Blachowicz, João Medeiros-Silva, Benoît Roux, Markus Weingarth   +8 more
doaj   +1 more source

Regulation of the Target of Rapamycin and Other Phosphatidylinositol 3-Kinase-Related Kinases by Membrane Targeting

Membranes, 2015
Phosphatidylinositol 3-kinase-related kinases (PIKKs) play vital roles in the regulation of cell growth, proliferation, survival, and consequently metabolism, as well as in the cellular response to stresses such as ionizing radiation or redox changes. In
Maristella De Cicco, Munirah S. Abd Rahim, Sonja A. Dames   +2 more
doaj   +1 more source

Formation of the β-barrel assembly machinery complex in lipid bilayers as seen by solid-state NMR

Nature Communications, 2018
The β-barrel assembly machinery (BAM) catalyzes β-barrel protein insertion into the outer membrane of E.coli. Here authors employ high-sensitivity solid-state NMR to reveal how the lipid environment and formation of the BamA-BamCDE complex affect BamA ...
Cecilia Pinto, Deni Mance, Tessa Sinnige, Mark Daniëls, Markus Weingarth, Marc Baldus   +5 more
doaj   +1 more source