Results 1 to 10 of about 183,677 (243)
Molecules, 2022 In crystalline molecular solids, in the absence of strong intermolecular interactions, entropy-driven processes play a key role in the formation of dynamically modulated transient phases.
Jiri Brus +3 more
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Protein NMR spectroscopy [PDF]
Current Biology, 1998 Protein NMR spectroscopy does have its limitations. It has so far been used mainly for small proteins with molecular weight of less than 30 kDa, although a handful of publications have now reported the NMR study of proteins up to 40–50 kDa. Larger proteins typically have faster relaxation rates, which results in fatter NMR peaks that tend to merge with
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Frontiers in Molecular Neuroscience, 2017 Alzheimer’s disease (AD) is an age-related neurodegenerative disorder, characterized by progressive loss of cognitive functions and memory. Excessive intake of aluminum chloride in drinking water is associated with amyloid plaques and neurofibrillary ...
Kamal Saba +6 more
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A distinct mechanism of C-type inactivation in the Kv-like KcsA mutant E71V
Nature Communications, 2022 Constriction of the selectivity filter is assumed to be a hallmark of C-type inactivation in K+ channels. Using different high-resolution methods, this study shows a distinct C-type inactivation mechanism in a KcsA mutant that emulates Kv-channels.
Ahmed Rohaim +8 more
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Membranes, 2015 Phosphatidylinositol 3-kinase-related kinases (PIKKs) play vital roles in the regulation of cell growth, proliferation, survival, and consequently metabolism, as well as in the cellular response to stresses such as ionizing radiation or redox changes. In
Maristella De Cicco +2 more
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Formation of the β-barrel assembly machinery complex in lipid bilayers as seen by solid-state NMR
Nature Communications, 2018 The β-barrel assembly machinery (BAM) catalyzes β-barrel protein insertion into the outer membrane of E.coli. Here authors employ high-sensitivity solid-state NMR to reveal how the lipid environment and formation of the BamA-BamCDE complex affect BamA ...
Cecilia Pinto +5 more
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Nature Communications, 2019 Processing bodies are membrane less organelles that contain enzymes involved in mRNA turnover, among them enhancer of decapping 3 (Edc3). Here the authors use solid- and solution-state NMR spectroscopy to characterize the structural organization and ...
Reinier Damman +5 more
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The Cell Surface, 2020 Cell walls are essential in the interaction of fungi with the (a)biotic environment and are also key to hyphal morphogenesis and mechanical strength. Here, we used solid-state NMR (ssNMR) spectroscopy combined with HPLC and GC–MS to study the structural ...
Helena Leona Ehren +5 more
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Probing Nuclear Dipole Moments and Magnetic Shielding Constants through 3-Helium NMR Spectroscopy
Physchem, 2022 Multinuclear NMR studies of the gaseous mixtures that involve volatile compounds and 3He atoms are featured in this review. The precise analyses of 3He and other nuclei resonance frequencies show linear dependencies on gas density.
Włodzimierz Makulski
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Shifts in the selectivity filter dynamics cause modal gating in K+ channels
Nature Communications, 2019 Spontaneous activity shifts at constant experimental conditions are widespread among ion channels but the molecular origins are poorly understood. Here, using solid-state NMR and MD simulations, the authors reveal that modal gating shifts in K + channels
Shehrazade Jekhmane +7 more
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