Results 91 to 100 of about 2,132,374 (267)

Facing and Overcoming Sensitivity Challenges in Biomolecular NMR Spectroscopy.

open access: yesAngewandte Chemie, 2015
In the Spring of 2013, NMR spectroscopists convened at the Weizmann Institute in Israel to brainstorm on approaches to improve the sensitivity of NMR experiments, particularly when applied in biomolecular settings.
J. Ardenkjaer-Larsen   +18 more
semanticscholar   +1 more source

ChemInform Abstract: Computational NMR Spectroscopy

open access: yesChemInform, 2012
AbstractReview: 194 refs.
Alkorta, Ibon, Elguero, José
openaire   +4 more sources

Cognitive Depletion in the Wild: a Case Study of NMR Spectroscopy Analysis [PDF]

open access: yesarXiv, 2017
NMR spectroscopy analysis is a detail-oriented analytic feat that typically requires specific domain expertise and hours of concentration. This work presents an ethnographic-style study of this analysis process in the context of evaluating the symptoms of cognitive depletion. The repeated, non-trivial decisions required by and the time-consuming nature
arxiv  

Visualizing transient dark states by NMR spectroscopy

open access: yesQuarterly Reviews of Biophysics (print), 2015
Myriad biological processes proceed through states that defy characterization by conventional atomic-resolution structural biological methods. The invisibility of these ‘dark’ states can arise from their transient nature, low equilibrium population ...
Nicholas J Anthis, G. Clore
semanticscholar   +1 more source

Enzyme Dynamics from NMR Spectroscopy

open access: yesAccounts of Chemical Research, 2015
Conspectus Biological activities of enzymes, including regulation or coordination of mechanistic stages preceding or following the chemical step, may depend upon kinetic or equilibrium changes in protein conformations.
A. Palmer
semanticscholar   +1 more source

NMR close to Mega-Bar Pressures [PDF]

open access: yesarXiv, 2018
The past 15 years have seen an astonishing increase in Nuclear Magnetic Resonance (NMR) sensitivity and accessible pressure range in high-pressure NMR experiments, owing to a series of new developments of NMR spectroscopy applied to the diamond anvil cell (DAC).
arxiv  

Ligand-receptor Interactions by NMR Spectroscopy [PDF]

open access: yesKemija u Industriji, 2008
Today NMR spectroscopy is a method of choice for elucidation of interactions between biomolecules and the potential ligands. Knowledge on these interactions is an essential prerequisite for the rational drug design. The most important contribution of NMR
Novak. P., Tepeš, P.
doaj  

Integrative determination of atomic structure of mutant huntingtin exon 1 fibrils implicated in Huntington disease

open access: yesNature Communications
Neurodegeneration in Huntington’s disease (HD) is accompanied by the aggregation of fragments of the mutant huntingtin protein, a biomarker of disease progression.
Mahdi Bagherpoor Helabad   +7 more
doaj   +1 more source

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