Results 31 to 40 of about 560,508 (333)

Structural Changes of Sodium Warfarin in Tablets Affecting the Dissolution Profiles and Potential Safety of Generic Substitution

open access: yesPharmaceutics, 2021
At present, the risk of generic substitutions in warfarin tablets is still being discussed. The aim of this study was to assess whether API interactions with commonly used excipients may affect the safety of generic replacement of warfarin sodium tablets.
Jan Muselík   +9 more
doaj   +1 more source

Structural changes in lipid-free humic acids during composting of sewage sludge [PDF]

open access: yes, 2005
Structural changes in humic acids (HAs), extracted after lipid removal from sewage sludge during composting, were investigated using various chemical methods (elemental analysis, Fourier transform infrared spectroscopy and 13C-nuclear magnetic resonance
Amir, Soumia   +3 more
core   +3 more sources

Impacts of Electroconvulsive Therapy on the Neurometabolic Activity in a Mice Model of Depression: An Ex Vivo 1H-[13C]-NMR Spectroscopy Study

open access: yesNeuroglia
Electroconvulsive therapy (ECT) is an effective treatment for severe and drug-resistant depression, yet its mode of action remains poorly understood.
Ajay Sarawagi   +5 more
doaj   +1 more source

A comprehensive framework of E2–RING E3 interactions of the human ubiquitin–proteasome system

open access: yesMolecular Systems Biology, 2009
Covalent attachment of ubiquitin to substrates is crucial to protein degradation, transcription regulation and cell signalling. Highly specific interactions between ubiquitin‐conjugating enzymes (E2) and ubiquitin protein E3 ligases fulfil essential ...
Sjoerd J L van Wijk   +6 more
doaj   +1 more source

A Spectral-Scanning Magnetic Resonance Imaging (MRI) Integrated System [PDF]

open access: yes, 2008
An integrated spectral-scanning magnetic resonance imaging (MRI) technique is implemented in a 0.12μm SiGe BiCMOS process. This system is designed for small-scale MRI applications with non-uniform and low magnetic fields.
Babakhani, Aydin   +2 more
core   +1 more source

High-resolution NMR studies of antibiotics in cellular membranes

open access: yesNature Communications, 2018
Antibiotics that target the peptidoglycan precursor lipid II are promising templates for next-generation antibiotics. Here authors use solid-state NMR and monitor lipid II-binding antibiotics, such as nisin, directly in cell membranes.
João Medeiros-Silva   +7 more
doaj   +1 more source

Resolving single molecule structures with Nitrogen-vacancy centers in diamond. [PDF]

open access: yes, 2015
We present theoretical proposals for two-dimensional nuclear magnetic resonance spectroscopy protocols based on Nitrogen-vacancy (NV) centers in diamond that are strongly coupled to the target nuclei.
Cai, J, Kost, M, Plenio, MB
core   +1 more source

Marked increase in PROP taste responsiveness following oral supplementation with selected salivary proteins or their related free amino acids [PDF]

open access: yes, 2013
The genetic predisposition to taste 6-n-propylthiouracil (PROP) varies among individuals and is associated with salivary levels of Ps-1 and II-2 peptides, belonging to the basic proline-rich protein family (bPRP).
Aragoni MC   +9 more
core   +6 more sources

Early Stage Diagnosis of Oral Cancer Using 1H NMR–Based Metabolomics

open access: yesNeoplasia: An International Journal for Oncology Research, 2009
Oral cancer is the eighth most common cancer worldwide and represents a significant disease burden. If detected at an early stage, survival from oral cancer is better than 90% at 5 years, whereas late stage disease survival is only 30%.
Stefano Tiziani   +2 more
doaj   +1 more source

Direct observation of dynamic protein interactions involving human microtubules using solid-state NMR spectroscopy

open access: yesNature Communications, 2020
Microtubule (MT) organization is regulated by many microtubule-associated proteins (MAPs) that contain intrinsically disordered regions. Here authors produce [13C, 15N] labeled, functional microtubules from human cells for solid-state NMR which allows ...
Yanzhang Luo   +8 more
doaj   +1 more source

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