Multi-Omics profiling identify NNMT in tumor endothelium as a key regulator of CD8⁺ T cell exhaustion via the TGF signaling pathway. [PDF]
Wang L +9 more
europepmc +1 more source
Effects of Low Methionine Intake on Gastric Ulcer in Patients and Mice: Role of the NNMT Pathway. [PDF]
Meng S +9 more
europepmc +1 more source
Fusobacterium nucleatum regulates nicotinamide metabolism via the upregulation of NNMT to activate PARP1/MAPK signalling in colitis-associated cancer. [PDF]
Lei J +7 more
europepmc +1 more source
Nicotinamide N-methyltransferase as a therapeutic target in taxane-resistant castration-resistant prostate cancer. [PDF]
Cevatemre B +7 more
europepmc +1 more source
PPARγ-dependent and -independent regulation of genes involved in hepatic methionine cycle in fasted or diet-induced obese mice. [PDF]
Hawro I +3 more
europepmc +1 more source
Stromal NNMT overexpression as an independent prognostic biomarker in lung adenocarcinoma and breast carcinoma. [PDF]
Wang Y +13 more
europepmc +1 more source
Nicotinamide N-Methyltransferase Inhibition Mitigates Cerulein-Induced Pancreatic Fibrosis via Galectin-3-Mediated Regulation of Stellate Cell Activation and Macrophage M2 Polarization in Mice. [PDF]
Ren N +7 more
europepmc +1 more source
Exploring the common ferroptosis-related genes and molecular mechanisms in periodontitis and systemic sclerosis via integrated bioinformatics and experimental analysis. [PDF]
Zhang S +7 more
europepmc +1 more source
Structure-Based Drug Discovery of Non-SAM-Mimetic Bisubstrate Inhibitors against Nicotinamide <i>N</i>‑Methyltransferase. [PDF]
Yoshida S +7 more
europepmc +1 more source
Identification of shared diagnostic biomarkers and molecular pathways between chronic kidney disease and renal cell carcinoma using transcriptomics and machine learning. [PDF]
Peng X +7 more
europepmc +1 more source

