Results 31 to 40 of about 3,155,563 (287)
Safety, toxicity and pharmacokinetic assessment of oral Withaferin-A in mice
Toxicology Reports, 2022 Withaferin-A (WA) is the principle component of Withania somnifera (Ashwagandha). It has several biological activities including anti-cancer, anti-diabetic, neuroprotective, hepatoprotective and immune-modulatory properties.
Saurabh Kumar Gupta +8 more
doaj +1 more source
No observed adverse effect level assay at 6 hours and 24 hours of 1-octen-3-ol exposure.
, 2023 No observed adverse effect level assay at 6 hours and 24 hours of 1-octen-3-ol exposure.
Babak Ebrahimi (4393384) +3 more
core +1 more source
Effect of imidacloprid on hepatotoxicity and nephrotoxicity in male albino mice
Toxicology Reports, 2014 Imidacloprid (IC) is a systemic insecticide related to the tobacco toxin nicotine. IC is a toxic substance frequently used into combat insects, rodents and plants pests and other creatures that can pose problems for agriculture.
Yasir Arfat +12 more
doaj +1 more source
Antioxidants, 2021 Chronic kidney disease (CKD) usually causes devastating healthy impacts on patients. However, the causes affecting the decline of kidney function are not fully revealed, especially the involvement of environmental pollutants.
Chia-Fang Wu +5 more
doaj +1 more source
Toxicity and Hypolipidemic Activity of Lansiumamide B in Mice [PDF]
Shipin KexueObjective: To explore the hypolipidemic activity and toxic side effect of lansiumamide B (LB) from chicken-heart shaped wampee (Clausena lansium) seeds in C57BL/6J mice fed on a high-fat-diet (HFD) model.
CHEN Danni, WANG Sainan, YIN Zhaochun, XU Zewen, GUO Xiaomin, LI Kangyuan, WANG Jiawei, CHEN Liping, CAO Yong, XIAO Suyao
doaj +1 more source
Safety Evaluation for Restorin® NMN, a NAD+ Precursor
Frontiers in Pharmacology, 2021 NAD+ is an abundant molecule in the body and vital to all living cells. NAD+ levels decline with age, and this decline correlates with age-related diseases. Therefore, sustaining NAD+ levels offers potential benefits to healthspan and longevity.
John Turner +3 more
doaj +1 more source
Subacute oral toxicity and bacterial mutagenicity study of Korean Red Ginseng oil
Journal of Ginseng Research, 2017 Background: Red ginseng oil (RGO) is produced by supercritical CO2 extraction of secondary products derived from Korean Red Ginseng extract. As the use of RGO has increased, product safety concerns have become more important.
Hwi Won Seo +5 more
doaj +1 more source
Statistical issues on the no-observed-adverse-effect level in categorical response. [PDF]
Environmental Health Perspectives, 1994 The determination of the value of the no-observed-adverse-effect level (NOAEL) when observed responses can be categorized by severity (categorical data) and sample sizes are small is discussed. The common situation of only two categories, where only the presence or absence of an effect is observed, is addressed first (dichotomous data). Three tests for
T, Yanagawa, Y, Kikuchi, K G, Brown
openaire +2 more sources
Scientific Reports, 2022 Currently, ERY974, a humanized IgG4 bispecific T cell-redirecting antibody recognizing glypican-3 and CD3, is in phase I clinical trials. After a first-in-human clinical trial of an anti-CD28 agonist monoclonal antibody resulting in severe life ...
Shun-ichiro Komatsu +14 more
doaj +1 more source
Molecules, 2018 Gelidium elegans extract (GEE) is derived from a red alga from the Asia–Pacific region, which has antioxidant, anti-adipogenic, and anti-hyperglycemic effects. However, detailed studies of the toxicology of GEE have not been performed.
Jia Choi +5 more
doaj +1 more source