Results 61 to 70 of about 880,423 (146)

Adverse effects of alternative therapy (minocycline, ofloxacin, and clofazimine) in multibacillary leprosy patients in a recognized health care unit in Manaus, Amazonas, Brazil Efeitos adversos das drogas (minociclina, ofloxacina e clofazimina) utilizadas no esquema alternativo para pacientes com hanseníase multibacilar, em unidade de referência, Manaus, Amazonas, Brasil

Anais Brasileiros de Dermatologia, 2013
BACKGROUND: After the introduction of the multidrug therapy, there was a decline in the coefficients of prevalence and detection of new cases of leprosy.
Marina Valente Maia, Maria da Graça Souza Cunha, Carolina Souza Cunha   +2 more
doaj  

A 90-day study of sub-chronic oral toxicity of 20 nm positively charged zinc oxide nanoparticles in Sprague Dawley rats

International Journal of Nanomedicine, 2014
Hark-Soo Park,1 Seon-Ju Kim,1 Taek-Jin Lee,1 Geon-Yong Kim,1 EunHo Meang,1 Jeong-Sup Hong,1 Su-Hyon Kim,1 Sang-Bum Koh,1 Seung-Guk Hong,1 Yle-Shik Sun,1 Jin Seok Kang,2 Yu-Ri Kim,3 Meyoung-Kon Kim,3 Jayoung Jeong,4 Jong-Kwon Lee,4 Woo-Chan Son,5 Jae-Hak ...
Park HS, Kim SJ, Lee TJ, Kim GY, Meang EH, Hong JS, Kim SH, Koh SB, Hong SG, Sun YS, Kang JS, Kim YR, Kim MK, Jeong JY, Lee JK, Son WC, Park JH   +16 more
doaj  

Lowest observed adverse effect level of pulmonary pathological alterations due to nitrous acid exposure in guinea pigs. [PDF]

Environ Health Prev Med, 2020
Ohyama M, Nishimura H, Azuma K, Minejima C, Takenaka N, Adachi S.   +5 more
europepmc   +1 more source

Safety of Repeated Administration of Xenogeneic Human Apoptotic State (Allocetra-OTS) in Sprague Dawley Rats

Pharmaceutics
Apoptotic cells possess immunomodulatory effects that can be utilized to treat imbalanced immune conditions. Information on the preclinical safety of such treatment is sparse. In this study, the safety of apoptotic cells (Allocetra-OTS) was assessed in a
Chen Ankri, Oren Hershkovitz, Liat Hershkovitz, Meital Brami, Ronnie Levy, Hadar Sarig, Einat Souli, Barak Reicher, Veronique Amor-Baroukh, Dror Mevorach, Abraham Nyska   +10 more
doaj   +1 more source

Clinical observation of responses to two plasma concentrations of tacrolimus in treatment of idiopathic membranous nephropathy stage Ⅱ

Linchuang shenzangbing zazhi, 2019
Objective To observe the clinical responses to two plasma concentrations of tacrolimus in treatment of idiopathic membranous nephropathy stageⅡ. Methods A total of 90 patients diagnosed with idiopathic membranous nephropathy stageⅡ through renal puncture
LI Xiao-yong
doaj  

Oral reference dose (RfD) derivation for five bisphenol A alternatives integrating BMD and NOAEL/LOAEL approaches

Ecotoxicology and Environmental Safety
Bisphenols (BPs) are widely used in plastic manufacturing, food packaging, and other industrial applications, with bisphenol A (BPA) being one of the most extensively produced chemicals globally.
Yan Xia, Wenhua Ma, Jing Cao, Yanpeng Gao, Yingxin Yu, Chaoyang Long   +5 more
doaj   +1 more source

Requirements for occupational exposure limits in psychosocial risk assessment: What we know, what we don’t know and what we can learn from other disciplines

Scandinavian Journal of Work, Environment & Health
OBJECTIVES: This discussion paper aims to provide recommendations for the development of occupational exposure limits (OEL) for psychosocial hazards.
Roman Pauli, Jessica Lang, Andreas Müller, Yacine Taibi, Thomas Kraus, Yannick Metzler   +5 more
doaj   +1 more source

DETERMINING THE NO-OBSERVED-ADVERSE-EFFECT LEVEL IN CATEGORICAL DATA

DETERMINING THE NO-OBSERVED-ADVERSE-EFFECT LEVEL IN CATEGORICAL DATA
We discuss the determination of the no-observed-adverse-effect level (NOAEL) from a categorical data. Recently a method which incorporated the order regtriction into the multiple testing was proposed in Brown and Erdreich [2]. The test is an exact test and computation ally involved for large samples.
openaire  

Effect of the neonicotinoid pesticide clothianidin at a no-observed-adverse-effect-level (NOAEL) dose on maternal behavior in pregnant mice and their female offspring. [PDF]

J Vet Med Sci
Nunobiki S, Yoshimoto A, Ito M, Yonoichi S, Hara Y, Ishida Y, Morishita R, Mantani Y, Yokoyama T, Hirano T, Ikenaka Y, Hoshi N.   +11 more
europepmc   +1 more source

No-observed-adverse-effect-level (NOAEL) clothianidin, a neonicotinoid pesticide, impairs hippocampal memory and motor learning associated with alteration of gene expression in cerebellum. [PDF]

J Vet Med Sci
Hara Y, Shoda A, Yonoichi S, Ishida Y, Murata M, Kimura M, Ito M, Nunobiki S, Yoshimoto A, Mantani Y, Yokoyama T, Hirano T, Ikenaka Y, Tabuchi Y, Hoshi N.   +14 more
europepmc   +1 more source