Results 21 to 30 of about 7,937 (163)
Preclinical and Toxicology Studies of LPM7100328, a Novel Oral GnRH Antagonist. [PDF]
Pharmacol Res PerspectABSTRACT LPM7100328 is a novel oral GnRH antagonist being developed for the prevention of premature luteinizing hormone (LH) surges in women undergoing controlled ovarian stimulation. The studies presented herein reported assessment of safety in favor of human clinical trials.
Wang Y +9 more
europepmc +2 more sources
Assessment of information as regards the toxicity of deoxynivalenol for horses and poultry
EFSA Journal, 2023 In 2017, the EFSA Panel on Contaminants in the Food Chain (CONTAM) adopted a Scientific Opinion on the risks for animal health related to the presence of deoxynivalenol (DON) and its acetylated and modified forms in food and feed.
EFSA Panel on Contaminants in the Food Chain (CONTAM) +20 more
doaj +1 more source
Effect of imidacloprid on hepatotoxicity and nephrotoxicity in male albino mice
Toxicology Reports, 2014 Imidacloprid (IC) is a systemic insecticide related to the tobacco toxin nicotine. IC is a toxic substance frequently used into combat insects, rodents and plants pests and other creatures that can pose problems for agriculture.
Yasir Arfat +12 more
doaj +1 more source
Assessment of information as regards the toxicity of fumonisins for pigs, poultry and horses
EFSA Journal, 2022 In 2018, the EFSA Panel on Contaminants in the Food Chain (CONTAM) adopted a Scientific Opinion on the risks for animal health related to the presence of fumonisins, their modified forms and hidden forms in feed. A no observed adverse effect level (NOAEL)
EFSA Panel on Contaminants in the Food Chain (CONTAM) +21 more
doaj +1 more source
Toxicology Reports, 2020 This study was performed to demonstrate a No Observed Adverse Effect Level (NOAEL) for an aqueous extract of Gryllus bimaculatus. According to other studies, using dried material or extract with ethanol or methanol determined a NOAEL dose of 1000 mg/kg ...
Su Hyun Yu +5 more
doaj +1 more source
The Scientific World Journal, 2022 Objective. Acute and subacute toxicity analysis of AND-2-HyP-β-CYD complex was conducted in Sprague-Dawley (SD) rats following oral and inhalation routes of administration. Methods and Results.
Shashi Chandrama Singh +6 more
doaj +1 more source
A No Observable Adverse Effects Level (NOAEL) for pigs fed melamine and cyanuric acid
Regulatory Toxicology and Pharmacology, 2011 Ingesting melamine adulterated milk products led to kidney stones in many infants in 2008. This differs from the renal failure caused by intratubular crystal formation after co-ingestion of melamine (MEL) and cyanuric acid (CYA) in adulterated pet foods in 2007.
Stine, Cynthia B. +9 more
openaire +2 more sources
Bitter orange (Citrus aurantium L.) extract subchronic 90-day safety study in rats
Toxicology Reports, 2017 Bitter orange (Citrus aurantium L.) extracts are widely used in dietary supplements and bitter oranges are used in various juices and food products. p-Synephrine, the primary active constituent, comprises approximately 90% of total protoalkaloids.
N.S. Deshmukh +4 more
doaj +1 more source
26-Week Repeated Dose Oral Toxicity Study of KCHO-1 in Sprague-Dawley Rats
Journal of Pharmacopuncture, 2019 Objectives: KCHO-1(Mecasin), also called Gamijakyakgamchobuja-tang originally, is a combination of some traditional herbal medicines in East Asia. This medicine has been used mainly for alleviating neuropathic pains for centuries in Korean traditional ...
Muhack Yang +10 more
doaj +1 more source
Toxicology Reports, 2023 INFAT®PLUS, is a sn-2 palmitate enriched fat ingredient intended for infant formula. A battery of toxicological studies was conducted in accordance with the Food Safety Toxicological Assessment GB-15193 (China), to confirm the safety of INFAT®PLUS.
Arava Lavie +9 more
doaj +1 more source