Results 31 to 40 of about 1,885,648 (256)

Subacute oral toxicity and bacterial mutagenicity study of Korean Red Ginseng oil

Journal of Ginseng Research, 2017
Background: Red ginseng oil (RGO) is produced by supercritical CO2 extraction of secondary products derived from Korean Red Ginseng extract. As the use of RGO has increased, product safety concerns have become more important.
Hwi Won Seo, Jae Hyun Suh, Seung-Ho So, Jong-Soo Kyung, Yong-Soon Kim, Chang-Kyun Han   +5 more
doaj   +1 more source

Effect of Hemodialysis on Plasma Glucose Profile and Plasma Level of Liraglutide in Patients with Type 2 Diabetes Mellitus and End-Stage Renal Disease: A Pilot Study [PDF]

, 2014
The effect of hemodialysis on the plasma glucose profile and liraglutide level after liraglutide injection was investigated in patients with diabetes and end-stage renal disease (ESRD).
Ishida, Hidenori, Nishimura, Rimei, Osonoi, Takeshi, Saito, Miyoko, Tamasawa, Atsuko, Tsujino, Daisuke, Utsunomiya, Kazunori   +6 more
core   +3 more sources

The effects of socioeconomic status and indices of physical environment on reduced birth weight and preterm births in Eastern Massachusetts [PDF]

, 2008
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work
A Ellaway, Ariana Zeka, B Ritz, B Ritz, BA Coull, BG Link, BL Williams, CI Li, DJ Barker, EH Ha, GLIMMIX, GR Alexander, I Kawachi, J Dejmek, JJ Collins, Joel Schwartz, JS Lucas, K Mortimer, K Sexton, KM Godfrey, LC Messer, LW Pickle, M Bobak, M Bobak, M Jerrett, M Maisonet, M Roorda-Knape, M Wilhelm, M Wilhelm, MassGIS-EOEA, ML Bell, MT Salam, MW Gillman, N Gouveia, N Krieger, N Krieger, N Krieger, N Krieger, N Krieger, N Schenker, NA Ponce, RC Gwynn, RM Burton, S Kanjilal, S Macintyre, Steve J Melly, SV Subramanian, TIGER, TJ Woodruff, X Wang, Y Zhu   +50 more
core   +3 more sources

Determination of starting dose of the T cell-redirecting bispecific antibody ERY974 targeting glypican-3 in first-in-human clinical trial

Scientific Reports, 2022
Currently, ERY974, a humanized IgG4 bispecific T cell-redirecting antibody recognizing glypican-3 and CD3, is in phase I clinical trials. After a first-in-human clinical trial of an anti-CD28 agonist monoclonal antibody resulting in severe life ...
Shun-ichiro Komatsu, Yoko Kayukawa, Yoko Miyazaki, Akihisa Kaneko, Hisashi Ikegami, Takahiro Ishiguro, Mikiko Nakamura, Werner Frings, Natsuki Ono, Kiyoaki Sakata, Toshihiko Fujii, Shohei Kishishita, Takehisa Kitazawa, Mika Endo, Yuji Sano   +14 more
doaj   +1 more source

Single, 14-Day, and 13-Week Repeated Dose Toxicity Studies of Daily Oral Gelidium elegans Extract Administration to Rats

Molecules, 2018
Gelidium elegans extract (GEE) is derived from a red alga from the Asia–Pacific region, which has antioxidant, anti-adipogenic, and anti-hyperglycemic effects. However, detailed studies of the toxicology of GEE have not been performed.
Jia Choi, Su-Jung Ryu, Kui-Jin Kim, Hyung-Min Kim, Hee-Chul Chung, Boo-Yong Lee   +5 more
doaj   +1 more source

Nintedanib for systemic sclerosis–associated interstitial lung disease [PDF]

, 2019
BackgroundInterstitial lung disease (ILD) is a common manifestation of systemic sclerosis and a leading cause of systemic sclerosis-related death. Nintedanib, a tyrosine kinase inhibitor, has been shown to have antifibrotic and antiinflammatory effects ...
Alves, Margarida, Azuma, Arata, Clerisme-Beaty, Emmanuelle, Distler, Oliver, Fischer, Aryeh, Gahlemann, Martina, Girard, Mannaig, Highland, Kristin B., Kuwana, Masataka, Maher, Toby M., Mayes, Maureen D., Raghu, Ganesh, Sauter, Wiebke, SENSCIS Trial Investigator, for the, Smith, Vanessa, Stowasser, Susanne, Tetzlaff, Kay   +16 more
core   +3 more sources

Safety evaluation of enriched fraction from leaves of Dillenia indica L. in BALB/c mice

Toxicology Reports, 2022
The enriched fraction derived from Dillenia indica L. (Dilleniaceae), also known as elephant apple was subjected to acute and sub-acute toxicological study to document its safety issues for use as fumigant. The enriched fractions were orally administered
Kabrambam D. Singh, Sarita Jena, Biswajit Patra, Thiyam B. Devi, Saurabh Chawla, Rupjyoti Bharali, Ajay Parida, Pulok K. Mukherjee, Yallappa Rajashekar   +8 more
doaj   +1 more source

The effects of donepezil in Alzheimer's disease - Results from a multinational trial [PDF]

, 1999
Donepezil has been shown to be well tolerated and to improve cognition and global function in patients with mild to moderately severe Alzheimer's disease (AD).
Burns, A., Friedhoff, L. T., Gauthier, S., Hecker, J., Möller, Hans-Jürgen, Petit, H., Rogers, S. L., Rossor, M.   +7 more
core   +1 more source

Safety assessment of (S)-Equol: Subchronic toxicity study in Sprague Dawley Rats

Toxicology Reports
(S)-Equol is a chemically synthesized nutraceutical compound and its consumption provides several health benefits for humans. The new nutraceutical, enantiopure (S)-Equol was studied for acute and sub-chronic toxicity in Sprague Dawley Rats.
Seethakallu Ramachandraiah AnandaKumar, Mukund Handral, Srinivas Seekallu   +2 more
doaj   +1 more source

Risk Assessment of Isoeugenol in Food Based on Benchmark Dose—Response Modeling

Toxics, 2023
Isoeugenol has recently been evaluated as possibly carcinogenic (Group 2B) by the WHO International Agency for Research on Cancer (IARC). In light of this evaluation, an updated risk assessment of this common food constituent was conducted using the ...
Thomas Quentin, Heike Franke, Dirk W. Lachenmeier   +2 more
doaj   +1 more source