Results 21 to 30 of about 914,178 (235)
Toxicology Reports, 2021 Diclofenac sodium salt (DSS) is a widely used nonsteroidal anti-inflammatory drug. The present study was performed under good laboratory practice (GLP) regulations to investigate the toxicity of DSS after 4 weeks of repeated intramuscular administration ...
Hyung-Sun Kim +5 more
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Toxicology Reports, 2021 Thinned immature fruit of the mango tree (Mangifera indica ‘Irwin’) are handled as waste. In this study, we conducted a 90-days toxicity study in male and female Sprague Dawley rats to evaluate the safety of a hot-water extract of thinned immature mango ...
Hayato Tajiri +6 more
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Repeated dose (90 days) oral toxicity study of ursolic acid in Han-Wistar rats
Toxicology Reports, 2020 Background: Ursolic acid (UA) has been used in alternative medicine for decades, and there has been a great interest in its medicinal properties. Despite this increased interest, a detailed long-term toxicity study has not been performed.
Lotte Geerlofs +3 more
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Safety, toxicity and pharmacokinetic assessment of oral Withaferin-A in mice
Toxicology Reports, 2022 Withaferin-A (WA) is the principle component of Withania somnifera (Ashwagandha). It has several biological activities including anti-cancer, anti-diabetic, neuroprotective, hepatoprotective and immune-modulatory properties.
Saurabh Kumar Gupta +8 more
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DETERMINING THE NO-OBSERVED-ADVERSE-EFFECT LEVEL IN CATEGORICAL DATA [PDF]
Bulletin of informatics and cybernetics, 1994 Summary: We discuss the determination of the no-observed-adverse-effect level (NOAEL) from categorical data. Recently a method which incorporated the order restriction into the multiple testing was proposed by \textit{K. G. Brown} and \textit{L. S. Erdreich} [Fund. Appl. Toxicology 13, 235-244 (1989)].
Nishiyama, Harutoshi, Yanagawa, Takashi
openaire +2 more sources
Effect of imidacloprid on hepatotoxicity and nephrotoxicity in male albino mice
Toxicology Reports, 2014 Imidacloprid (IC) is a systemic insecticide related to the tobacco toxin nicotine. IC is a toxic substance frequently used into combat insects, rodents and plants pests and other creatures that can pose problems for agriculture.
Yasir Arfat +12 more
doaj +1 more source
Antioxidants, 2021 Chronic kidney disease (CKD) usually causes devastating healthy impacts on patients. However, the causes affecting the decline of kidney function are not fully revealed, especially the involvement of environmental pollutants.
Chia-Fang Wu +5 more
doaj +1 more source
Toxicity and Hypolipidemic Activity of Lansiumamide B in Mice [PDF]
Shipin KexueObjective: To explore the hypolipidemic activity and toxic side effect of lansiumamide B (LB) from chicken-heart shaped wampee (Clausena lansium) seeds in C57BL/6J mice fed on a high-fat-diet (HFD) model.
CHEN Danni, WANG Sainan, YIN Zhaochun, XU Zewen, GUO Xiaomin, LI Kangyuan, WANG Jiawei, CHEN Liping, CAO Yong, XIAO Suyao
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Safety Evaluation for Restorin® NMN, a NAD+ Precursor
Frontiers in Pharmacology, 2021 NAD+ is an abundant molecule in the body and vital to all living cells. NAD+ levels decline with age, and this decline correlates with age-related diseases. Therefore, sustaining NAD+ levels offers potential benefits to healthspan and longevity.
John Turner +3 more
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Taiwanese Journal of Obstetrics & Gynecology, 2023 Objective: The data on the association between phthalates and breast cancer risk remains inconsistent. This study aimed to explore the possible mechanism of low-dose exposures of phthalates, including Butyl benzyl phthalate (BBP), di(n-butyl) phthalate ...
Fang-Ping Chen +2 more
doaj +1 more source