Results 31 to 40 of about 914,178 (235)
Subacute oral toxicity and bacterial mutagenicity study of Korean Red Ginseng oil
Journal of Ginseng Research, 2017 Background: Red ginseng oil (RGO) is produced by supercritical CO2 extraction of secondary products derived from Korean Red Ginseng extract. As the use of RGO has increased, product safety concerns have become more important.
Hwi Won Seo +5 more
doaj +1 more source
Statistical issues on the no-observed-adverse-effect level in categorical response. [PDF]
Environmental Health Perspectives, 1994 The determination of the value of the no-observed-adverse-effect level (NOAEL) when observed responses can be categorized by severity (categorical data) and sample sizes are small is discussed. The common situation of only two categories, where only the presence or absence of an effect is observed, is addressed first (dichotomous data). Three tests for
T, Yanagawa, Y, Kikuchi, K G, Brown
openaire +2 more sources
Scientific Reports, 2022 Currently, ERY974, a humanized IgG4 bispecific T cell-redirecting antibody recognizing glypican-3 and CD3, is in phase I clinical trials. After a first-in-human clinical trial of an anti-CD28 agonist monoclonal antibody resulting in severe life ...
Shun-ichiro Komatsu +14 more
doaj +1 more source
Molecules, 2018 Gelidium elegans extract (GEE) is derived from a red alga from the Asia–Pacific region, which has antioxidant, anti-adipogenic, and anti-hyperglycemic effects. However, detailed studies of the toxicology of GEE have not been performed.
Jia Choi +5 more
doaj +1 more source
Safety evaluation of enriched fraction from leaves of Dillenia indica L. in BALB/c mice
Toxicology Reports, 2022 The enriched fraction derived from Dillenia indica L. (Dilleniaceae), also known as elephant apple was subjected to acute and sub-acute toxicological study to document its safety issues for use as fumigant. The enriched fractions were orally administered
Kabrambam D. Singh +8 more
doaj +1 more source
Safety assessment of (S)-Equol: Subchronic toxicity study in Sprague Dawley Rats
Toxicology Reports(S)-Equol is a chemically synthesized nutraceutical compound and its consumption provides several health benefits for humans. The new nutraceutical, enantiopure (S)-Equol was studied for acute and sub-chronic toxicity in Sprague Dawley Rats.
Seethakallu Ramachandraiah AnandaKumar +2 more
doaj +1 more source
Risk Assessment of Isoeugenol in Food Based on Benchmark Dose—Response Modeling
Toxics, 2023 Isoeugenol has recently been evaluated as possibly carcinogenic (Group 2B) by the WHO International Agency for Research on Cancer (IARC). In light of this evaluation, an updated risk assessment of this common food constituent was conducted using the ...
Thomas Quentin +2 more
doaj +1 more source
The Journal of Toxicological Sciences, 2020 Information on the safety of chemical substances in patients with various preexisting conditions remains limited. Acetaminophen was added to the basal diet at 0, 80, 253, 800, 2530, or 8000 ppm and administered to type 2 diabetes mellitus rats (GK/Jcl) and the control male rats (Wistar) for 13 weeks.
Kishi, Sosuke +8 more
openaire +3 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
lowest observed adverse effect level
, 2014 Citation: 'lowest observed adverse effect level' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.LT06909 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire +2 more sources