Results 191 to 200 of about 6,450 (220)

Nobiletin enhances differentiation and lipolysis of 3T3-L1 adipocytes

Biochemical and Biophysical Research Communications, 2007
Nobiletin is a polymethoxylated flavone found in certain citrus fruits. Here we demonstrate that nobiletin enhance differentiation of 3T3-L1 preadipocytes. Nobiletin dose-dependently increased accumulation of lipid droplets in adipocytes. Quantitative RT-PCR analyses indicated that nobiletin increased the expression of genes critical for acquisition of
Takeshi, Saito, Daigo, Abe, Keizo, Sekiya   +2 more
exaly   +3 more sources

Mechanism of Neurotrophic Action of Nobiletin in PC12D Cells

Biochemistry, 2005
Nobiletin is a nonpeptide compound with a low molecular weight from a citrus fruit and has the activity to rescue bulbectomy-induced memory impairment. Here we describe that nobiletin itself induces neurite outgrowth in PC12D cells, a rat pheochromocytoma cell line, like NGF, and the molecular mechanism of its neurotrophic action.
Hiroyuki, Nagase, Tohru, Yamakuni, Kentaro, Matsuzaki, Yuji, Maruyama, Jiro, Kasahara, Yoshimi, Hinohara, Shunzo, Kondo, Yoshihiro, Mimaki, Yutaka, Sashida, A William, Tank, Kohji, Fukunaga, Yasushi, Ohizumi   +11 more
openaire   +2 more sources

Nobiletin alleviates methotrexate-induced hepatorenal toxicity in rats

Biotechnic & Histochemistry
We investigated the possible ameliorative effects of nobiletin (NBL) against methotrexate (MTX)-induced hepatorenal toxicity in rats. Twenty-eight Wistar albino rats were randomly divided into four groups, namely: Control; MTX (administered 20 mg/kg MTX); MTX+NBL (administered 20 mg/kg MTX and 10 mg/kg NBL per day); and NBL (administered 10 mg/kg/day ...
Filiz Kazak, Ahmet Uyar, Pinar Coskun, Turan Yaman   +3 more
openaire   +2 more sources

Ca2+-induced whey protein emulgels for the encapsulation of crystalline nobiletin: Effect of nobiletin crystals on the viscoelasticity

Food Hydrocolloids, 2019
Abstract Due to the high crystallization, nobiletin was encapsulated by Ca2+-induced whey protein concentrate (WPC)-stabilized emulgels. Hydroxypropyl methylcellulose (HPMC) was used to regulate the interfacial properties of emulsions and viscoelasticity of emulgels.
Yan Hu, Qiao Shu, Fei Liu, Lingling Lei, Bin Li, Yanping Cao, Yan Li   +6 more
openaire   +1 more source

Nobiletin

2021
Hari Prasad Devkota, Anjana Adhikari-Devkota, Amina Ibrahim Dirar, Tarun Belwal   +3 more
openaire   +1 more source

A Flavonoid has Neuroprotective Effect: Nobiletin

2017
The use offlavonoids promises new approach for the treatment of neurodegenerativediseases. Nobiletine is a polymethoxy flavonoid found in the citrus peel. Theneuroprotective effect of nobiletin has been demonstrated in vivo and in vitro.Nobiletine affects the signaling cascades associated with learning and memory,alleviates neurodegeneration by ...
YARIM, Gül Fatma, ÇENESİZ, Metin, YARIM, Murat, KAZAK, Filiz   +3 more
openaire   +1 more source

191. Nobiletin. Part II

Journal of the Chemical Society (Resumed), 1938
Robert Robinson, Kwong-Fong Tseng
openaire   +1 more source

Hydrogel-based encapsulation strategy for nobiletin stabilization

Journal of Molecular Liquids, 2023
Bing Cui, Di Wu, Bin Zhou, Kongdi Zhu, Yaqiong Pei, Bin Li, Hongshan Liang   +6 more
openaire   +1 more source

Nobiletin Is Main Fungistat in Tangerines Resistant to Mal Secco

Science, 1967
A number of crystalline compounds isolated from peel of tangerines resistant to "mal secco" were characterized and tested for fungistatic activity toward Deuterophoma tracheiphila . Nobiletin exhibited strong fungistatic activity, tangeritin was weakly active, and hesperidin slightly stimulated fungal growth.
openaire   +2 more sources

Assessment of Oral Bioavailability and Biotransformation of Emulsified Nobiletin Using In Vitro and In Vivo Models

Journal of Agricultural and Food Chemistry, 2020
Man Zhang, Jie Xiao, Yong Cao
exaly