Results 171 to 180 of about 4,723 (202)

Ca2+-induced whey protein emulgels for the encapsulation of crystalline nobiletin: Effect of nobiletin crystals on the viscoelasticity

Food Hydrocolloids, 2019
Abstract Due to the high crystallization, nobiletin was encapsulated by Ca2+-induced whey protein concentrate (WPC)-stabilized emulgels. Hydroxypropyl methylcellulose (HPMC) was used to regulate the interfacial properties of emulsions and viscoelasticity of emulgels.
Yan Hu, Qiao Shu, Fei Liu, Lingling Lei, Bin Li, Yanping Cao, Yan Li   +6 more
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Identification of nobiletin, a polymethoxyflavonoid, as an enhancer of adiponectin secretion

Bioorganic & Medicinal Chemistry Letters, 2009
Adiponectin, an adipocyte-derived protein with insulin-sensitizing, anti-diabetic and anti-atherogenic activities, is known to be induced during adipocyte differentiation. Nobiletin, a citrus polymethoxy flavonoid, was found to induce the differentiation of ST-13 preadipocytes into mature adipocytes and enhance the production of adiponectin protein at ...
Kazuhiro, Kunimasa, Sachi, Kuranuki, Nobuyasu, Matsuura, Nozomi, Iwasaki, Megumi, Ikeda, Akira, Ito, Yutaka, Sashida, Yoshihiro, Mimaki, Masamichi, Yano, Mayumi, Sato, Yasuhiro, Igarashi, Tsutomu, Oikawa   +11 more
openaire   +2 more sources

Nobiletin mitigates NAFLD via lipophagy and inflammation

Food & Function, 2022
Nobiletin was found to mitigate nonalcoholic fatty liver disease by enhancing TFEB-mediated lipophagy, alleviating NLRP3 inflammasome and modulating macrophages polarization.
Xushan Yang, Yudi Deng, Yali Tu, Dongliang Feng, Wenzhen Liao   +4 more
openaire   +2 more sources

How can nobiletin prevent obesity?

Expert Review of Endocrinology & Metabolism, 2011
. However, elucidation of the effectiveness of flavonoid-containing foods in humans is confounded by the heterogeneity in flavonoid metabo-lism, potentially resulting in sub-therapeutic doses. In addition, the content of flavonoids in foods is variable and a considerable range exists in the bioavailability of flavonoids among human ...
Erin E Mulvihill, Murray W Huff
openaire   +1 more source

Nobiletin: a citrus flavonoid displaying potent physiological activity

Acta Crystallographica Section C Structural Chemistry, 2016
Nobiletin [systematic name: 2-(3,4-dimethoxyphenyl)-5,6,7,8-tetramethoxy-4H-chromen-4-one; C21H22O8] is a flavonoid found in citrus peels, and has been reported to show a wide range of physiological properties, including anti-inflammatory, anticancer and antidementia activities. We have solved the crystal structure of nobiletin, which revealed that the
Shuji, Noguchi, Haruka, Atsumi, Yasunori, Iwao, Toshiyuki, Kan, Shigeru, Itai   +4 more
openaire   +2 more sources

Nobiletin

2021
Hari Prasad Devkota, Anjana Adhikari-Devkota, Amina Ibrahim Dirar, Tarun Belwal   +3 more
openaire   +1 more source

Multifunctional role of Nobiletin in cancer chemoprevention

2023
The diversity of highly bioactive and pharmacologically active natural products which recognize essential biological targets having exquisite specificity, constitutes a massive pharmacological database for discovery of valuable drugs. The rapid accumulation of information has revealed chemopreventive role of nobiletin against wide variety of cancers ...
Malik D., Attar, Rukset, Ozbey U., Romero M., Yulaevna I., Purenovic, Jelena   +5 more
openaire   +1 more source

[Effect of nobiletin on tubulin polymerization in vitro].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2009
To investigate the possible mechanisms of nobiletin for anticancer by studying the inhibition effects of nobiletin on tubulin polymerization.In vitro nobiletin was added into the tubulin polymerization-depolymerization system and the absorption values were recorded at 350 nm under 37 degrees C.As compared with controls, the absorption values in ...
Yi, Liu, Ke-Feng, Wu, Yan-Ping, Li
openaire   +1 more source

Synthesis of the polymethoxyflavones nobiletin, tangeretin, isosinensetin, and gardenin A–D

Organic & Biomolecular Chemistry
A practical synthesis of 2′-hydroxy-3′,4′,5′,6′-tetramethoxyacetophenone, the key intermediate for the total synthesis of various polymethoxyflavones, was developed.
Cheng-Hang Liu, Mengyang Xu, Jianke Du, Yang Ni, Qiyun Luo, Ziyan Wang, Wenyue Tan, Yunfang He, Linrun Zhang, Xiaodong Jia, Xingzeng Zhao   +10 more
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191. Nobiletin. Part II

Journal of the Chemical Society (Resumed), 1938
Robert Robinson, Kwong-Fong Tseng
openaire   +1 more source