Results 11 to 20 of about 5,740 (145)

Comprehensive profiling of lncRNAs in the immune response of largemouth bass to Nocardia Seriolae infection [PDF]

Comparative Immunology Reports
Long noncoding RNAs (lncRNAs) are crucial regulators of various biological processes. However, it remains unclear how lncRNAs can be involved in the immune response to Nocardia seriolae invasion in largemouth bass (Micropterus salmoides).
Xiaona Fu, Longsheng Zhang, Keqi Li, Zhigang Liu, Jikui Wu, Junling Zhang   +5 more
doaj   +4 more sources

Pathogenicity and whole-genome analysis of a Siniperca chuatsi-derived Nocardia seriolae strain [PDF]

Frontiers in Microbiology
A bacterial strain (No. 20230510) was isolated from the kidneys of diseased Siniperca chuatsi in Guangxi, China, since 2023. Artificial infection experiments demonstrated that this strain caused the observed disease in S. chuatsi.
Liting Chen, Liting Chen, Xin Yan, Xin Yan, Yongju Luo, Yongju Luo, Zhuanling Lu, Zhuanling Lu, Xinxian Wei, Xinxian Wei, Zhanyang Tang, Zhanyang Tang, Liqun Xia, Fuyan Chen, Fuyan Chen, Ming Li, Ming Li, Zhongbao Guo, Zhongbao Guo, Zhichang He, Zhichang He, Ting Huang, Ting Huang   +22 more
doaj   +7 more sources

A bivalent oral yeast vaccine displaying Nocardia seriolae FHA and LMBV MCP confers protection in largemouth bass (Micropterus salmoides) [PDF]

Frontiers in Immunology
Largemouth bass ranavirus (LMBV) and Nocardia seriolae are major pathogens affecting largemouth bass (Micropterus salmoides), causing significant economic losses.
Jianfei Lu, Jianfei Lu, Boge Gu, Boge Gu, Pengzhen Yu, Pengzhen Yu, Jiong Chen, Jiong Chen   +7 more
doaj   +3 more sources

Evaluation of a multi-epitope vaccine for Nocardia seriolae in Micropterus salmoides

Aquaculture Reports
Nocardia seriolae can cause chronic granulomatous bacterial disease in fish, resulting in tissue necrosis. Currently, there is no effective method to control N. seriolae infection, which has led to significant economic losses in the aquaculture industry.
Yingbing Su, Xiaoman Qin, Lin Zhu, Feng Liu   +3 more
doaj   +4 more sources

Efficacy of Whole-Cell-Based Mono- and Bi-Valent Vaccines Against Nocardia seriolae and Aeromonas veronii in Largemouth Bass, Micropterus salmoides [PDF]

Vaccines
Background/Objectives: Nocardia seriolae and Aeromonas veronii are two important pathogens that can affect a wide range of fish species and cause substantial economic losses.
Qiushi Zhang, Nengbin Zhu, Ruiping Xu, Eakapol Wangkahart, Lin Zhang, Lihe Liu, Rui Wang, Zhen Xu, Weiguang Kong, Hongsen Xu   +9 more
doaj   +3 more sources

Arginine-Mediated Liver Immune Regulation and Antioxidant Defense in Largemouth Bass (Micropterus salmoides): Multi-Omics Insights into Metabolic Remodeling During Nocardia seriolae Infection [PDF]

Antioxidants
The liver of fish is an essential metabolic organ that also serves an immune regulatory role. In this study, we constructed a model of largemouth bass (Micropterus salmoides) infected with Nocardia seriolae by injection to explore the immune and ...
Yu-Long Sun, Shuai-Liang Zhang, Feng-Feng Zhou, Yuan-Xin Qian, Yang He, Run-Zhe Zhang, Fen Dong, Qiang Chen, Han-Ying Xu, Ji-Teng Wang, Yu-Ting Deng, Tao Han   +11 more
doaj   +3 more sources

Interleukin 34 Serves as a Novel Molecular Adjuvant against Nocardia Seriolae Infection in Largemouth Bass (Micropterus Salmoides) [PDF]

Vaccines, 2020
DNA vaccines have been widely employed in controlling viral and bacterial infections in mammals and teleost fish. Co-injection of molecular adjuvants, including chemokines, cytokines, and immune co-stimulatory molecules, is one of the potential ...
Huy Hoa Hoang, Pei-Chi Wang, Shih-Chu Chen   +2 more
doaj   +3 more sources

Macleaya cordata Alkaloids Sanguinarine and Chelerythrine Inhibit Nocardia seriolae by Disrupting Cell Envelope Integrity and Energy Metabolism: Insights from Transcriptomic Analysis [PDF]

Microorganisms
Nocardia seriolae infection poses a serious threat to largemouth bass (Micropterus salmoides) aquaculture, owing to the lack of effective control strategies.
Lei Huang, Xue Cai, Kuan Chu, Xuemei Yuan, Xianqi Peng, Jing Chen, Xialian Bu, Chen Niu, Dawei Song, Jiayun Yao   +9 more
doaj   +3 more sources

Single-strain probiotics enhance growth, anti-pathogen immunity, and resistance to Nocardia seriolae in grey mullet (Mugil cephalus) via gut microbiota modulation [PDF]

Animal Microbiome
Grey mullet (Mugil cephalus) aquaculture is economically vital due to the high value of its roe. However, it faces significant risks from disease outbreaks, particularly from Nocardia seriolae.
Ching-Hung Chan, Li-Han Chen, Kuang-Yu Chen, I-Hung Chen, Kung-Ta Lee, Liang-Chuan Lai, Mong-Hsun Tsai, Eric Y. Chuang, Ming-Tse Lin, Tsong-Rong Yan   +9 more
doaj   +3 more sources

Structure-guided discovery of novel dUTPase inhibitors with anti-Nocardia activity by computational design [PDF]

Journal of Enzyme Inhibition and Medicinal Chemistry
The zoonosis caused by Nocardia is increasing seriously. But commonly used antibiotic drugs often lead to resistance. N. seriolae dUTPase (NsdUTPase) plays a key role in the proliferation of Nocardia, and was regarded as a potent drug target.
Zhi-Zheng Wang, Jun Weng, Jing Qi, Xin-Xin Fu, Ban-Bin Xing, Yang Hu, Chun-Hsiang Huang, Chin-Yu Chen, Zigong Wei   +8 more
doaj   +3 more sources