Informing About the Nocebo Effect Affects Patients’ Need for Information About Antidepressants—An Experimental Online Study [PDF]
Relevance: Understanding patients’ informational needs and adapting drug-related information are the prerequisites for a contextualized informed consent. Current information practices might rather harm by inducing nocebo effects.Objective: To investigate
Yvonne Nestoriuc +6 more
doaj +4 more sources
Preventing adverse events of chemotherapy for gastrointestinal cancer by educating patients about the nocebo effect: a randomized-controlled trial [PDF]
Background Adverse events of chemotherapy may be caused by pharmacodynamics or psychological factors such as negative expectations, which constitute nocebo effects. In a randomized controlled trial, we examined whether educating patients about the nocebo
T. Michnevich +5 more
doaj +4 more sources
Differential Classical Conditioning of the Nocebo Effect: Increasing Heat-Pain Perception without Verbal Suggestions [PDF]
Background: Nocebo effects, including nocebo hyperalgesia, are a common phenomenon in clinical routine with manifold negative consequences. Both explicit expectations and learning by conditioning are known to induce nocebo effects, but the specific role ...
Anne-Kathrin Bräscher +7 more
doaj +4 more sources
Preventing adverse events of chemotherapy by educating patients about the nocebo effect (RENNO study) – study protocol of a randomized controlled trial with gastrointestinal cancer patients [PDF]
Background Patients undergoing chemotherapy are highly burdened by side effects. These may be caused by the pharmacodynamics of the drug or be driven by psychological factors such as negative expectations or pre-conditioning, which reflect nocebo effects.
Julia Quidde +7 more
doaj +4 more sources
Psychological distress, perceived stress and nocebo effect (multifood adverse reaction) in irritable bowel syndrome patients [PDF]
BACKGROUND: Psychological distress and perceived stress may complicate the clinical presentation, course, and treatment of patients with functional gastrointestinal disorders.
Hamid Nasiri-Dehsorkhi +3 more
doaj +2 more sources
Minimizing Drug Adverse Events by Informing About the Nocebo Effect—An Experimental Study [PDF]
Relevance: Informing patients about potential adverse events as part of the informed consent may facilitate the development of nocebo-driven drug adverse events (nocebo side effects).Objective: To investigate whether informing about the nocebo effect ...
Yiqi Pan +4 more
doaj +2 more sources
Nocebo Effect in Randomized Clinical Trials of Antidepressants in Children and Adolescents: Systematic Review and Meta-Analysis [PDF]
Objective:: To compare the incidence of adverse events between active and placebo arms of randomized clinical trials in depressive children and adolescents (C&A) with antidepressant treatments, in order to look for similarities in both groups that allow ...
Becerra, Lino +7 more
core +4 more sources
The nocebo effect as a source of bias in the assessment of treatment effects [version 2; peer review: 1 approved, 2 approved with reservations] [PDF]
The term nocebo effect refers to the harmful outcomes that result from people’s negative beliefs, anticipations, or experiences related to the treatment rather than the pharmacological properties of the treatment.
Karolina Wartolowska
doaj +2 more sources
Nonmedical Switching From Originators to Biosimilars: Does the Nocebo Effect Explain Treatment Failures and Adverse Events in Rheumatology and Gastroenterology? [PDF]
The act of nonmedical switching, defined as switching stable patients who are generally doing well with their current therapy from an originator biologic to its biosimilar, has been endorsed as a reasonable treatment strategy.
Roy Fleischmann +4 more
doaj +2 more sources
Editorial: The nocebo effect and its consequences for clinical trials and clinical practice. [PDF]
Wartolowska K, Colloca L, Amanzio M.
europepmc +3 more sources

