Informing About the Nocebo Effect Affects Patients’ Need for Information About Antidepressants—An Experimental Online Study [PDF]
Relevance: Understanding patients’ informational needs and adapting drug-related information are the prerequisites for a contextualized informed consent. Current information practices might rather harm by inducing nocebo effects.Objective: To investigate
Yvonne Nestoriuc +6 more
doaj +5 more sources
Preventing adverse events of chemotherapy for gastrointestinal cancer by educating patients about the nocebo effect: a randomized-controlled trial [PDF]
Background Adverse events of chemotherapy may be caused by pharmacodynamics or psychological factors such as negative expectations, which constitute nocebo effects. In a randomized controlled trial, we examined whether educating patients about the nocebo
T. Michnevich +5 more
doaj +5 more sources
Adverse nocebo responses can cause harm to patients and interfere with treatment adherence and effects in both clinic practice and clinical trials. Nocebo responses refer to negative outcomes to active medical treatments in clinical trials or practice that cannot be explained by the treatment's pharmacologic effects.
Colloca L.
europepmc +4 more sources
Editorial: The nocebo effect and its consequences for clinical trials and clinical practice. [PDF]
COPYRIGHT © 2023 Wartolowska, Colloca and Amanzio. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Wartolowska K, Colloca L, Amanzio M.
europepmc +4 more sources
Psychological distress, perceived stress and nocebo effect (multifood adverse reaction) in irritable bowel syndrome patients [PDF]
BACKGROUND: Psychological distress and perceived stress may complicate the clinical presentation, course, and treatment of patients with functional gastrointestinal disorders.
Hamid Nasiri-Dehsorkhi +3 more
doaj +3 more sources
Mitigating the Nocebo Effect in Biosimilar Use and Switching: A Systematic Review. [PDF]
In the context of biosimilar use and switching, a patient’s negative perception of a biosimilar might trigger a nocebo effect, where negative expectations unrelated to its pharmacologic action may lead to worsened symptoms, resulting in less perceived ...
Car E +6 more
europepmc +4 more sources
Nocebo effect in inhaler use: Patients' beliefs and treatment adherence [PDF]
Background: The nocebo effect refers to the experience of nonspecific symptoms attributed to medical treatments, which cannot be explained by the pharmacological effects of the medication.
Eduardo Garcia-Pachon +4 more
doaj +3 more sources
Multidisciplinary team intervention to reduce the nocebo effect when switching from the originator infliximab to a biosimilar. [PDF]
Objectives To evaluate an intervention to reduce the nocebo effect (NE) when switching from the originator infliximab (OI) to the infliximab biosimilar SB2 in chronic inflammatory rheumatic disease (CIRD).
Petit J +9 more
europepmc +4 more sources
Why Do I Get Side Effects? Personalized (N-of-1) Trials for Statin Intolerance and the Nocebo Effect. [PDF]
The ability of statins to reduce the morbidity and mortality of cardiovascular disease has ensured that they are among the most prescribed drugs in modern medicine.
Howard JP, Wood FA, Francis DP.
europepmc +4 more sources
Differential Classical Conditioning of the Nocebo Effect: Increasing Heat-Pain Perception without Verbal Suggestions [PDF]
Background: Nocebo effects, including nocebo hyperalgesia, are a common phenomenon in clinical routine with manifold negative consequences. Both explicit expectations and learning by conditioning are known to induce nocebo effects, but the specific role ...
Anne-Kathrin Bräscher +7 more
doaj +4 more sources

