Results 61 to 70 of about 15,094,517 (221)

Pain Anticipation and Nocebo-Related Responses: A Descriptive Mini-Review of Functional Neuroimaging Studies in Normal Subjects and Precious Hints on Pain Processing in the Context of Neurodegenerative Disorders

Frontiers in Pharmacology, 2019
The exacerbation of a clinical condition or the occurrence of negative symptoms after an inert substance dispensation or a sham treatment is known as “nocebo effect.” Nocebo is the psychobiological effect due to the negative psychosocial context that ...
Martina Amanzio, Martina Amanzio, Sara Palermo, Sara Palermo   +3 more
doaj   +1 more source

Expectation modulates the effect of deep brain stimulation on motor and cognitive function in tremor-dominant Parkinson's disease. [PDF]

PLoS ONE, 2013
Expectation contributes to placebo and nocebo responses in Parkinson's disease (PD). While there is evidence for expectation-induced modulations of bradykinesia, little is known about the impact of expectation on resting tremor. Subthalamic nucleus (STN)
Ariane Keitel, Stefano Ferrea, Martin Südmeyer, Alfons Schnitzler, Lars Wojtecki   +4 more
doaj   +1 more source

Non‐Invasive Brain Stimulation in Chronic Pain: Current Evidence, Network Perspectives and Paths to Personalization

Sensory Neuroscience, EarlyView.
Chronic pain reflects maladaptive network interactions across sensory, salience/affective, and descending modulatory pathways. We review evidence for non‐invasive brain stimulation—rTMS, tES, and low‐intensity focused ultrasound—highlighting modest, variable, and often short‐lived analgesic effects under conventional protocols.
Fabian Broecker, Sven Vanneste
wiley   +1 more source

Placebo and the law of identification

Frontiers in Psychiatry
Thousands of essays and studies have been published on placebo and nocebo. Yet, despite this plethora of information, we are not much closer to a comprehensive understanding of the fundamental mechanism producing placebo and nocebo effects than we were ...
Steve F. Bierman, Andrew Weil, Stephen Dahmer   +2 more
doaj   +1 more source

Nocebo in Biosimilars and Generics in Neurology: A Systematic Review

Frontiers in Pharmacology, 2019
Background: Nocebo refers to adverse events related to patients’ negative expectations and previous experiences, mediated by several neurobiological pathways within the brain.
Ioanna Spanou, Theodoros Mavridis, Dimos D. Mitsikostas   +2 more
doaj   +1 more source

Underappreciated power. Placebo and nocebo in medicine

Медицинский совет, 2020
The term placebo is defined as a substance with no therapeutic effect that improves health by convincing the patient that the substance is effective. The term comes from the Latin “placere”, meaning “I will delight” or “do good”.
A. O. Bueverov
doaj   +1 more source

Nocebo response intensity and influencing factors in the randomized clinical trials of irritable bowel syndrome: A systematic review and meta-analysis

Frontiers in Medicine, 2022
ObjectiveTo estimate the magnitude of the nocebo response and explore its influencing factors in irritable bowel syndrome (IBS).MethodsThe PubMed, Embase, and Cochrane Library databases were searched up to March 2021.
Ruijie Li, Fuping Chen, Xuanxuan He, Yuqing Feng, Qiaoqiao Pei, Dongke Wang, Xinghuang Liu, Jinsong Liu, Xiaohua Hou, Tao Bai   +9 more
doaj   +1 more source

Psilocybin in alcohol use disorder and comorbid depressive symptoms: Results from a feasibility randomized clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psilocybin has emerged as a potential treatment for alcohol use disorder (AUD), but early efficacy data are inconsistent. Depression following alcohol detoxification significantly increases the risk of relapse. This pilot study aimed to evaluate the feasibility, acceptability, and preliminary efficacy of psilocybin‐assisted
Amandine Luquiens, Dahbia Belahda, Carine Graux, Noe Igounenc, Chris Serrand, Paul Rochefort, Thibault Mura, Felix Sergent   +7 more
wiley   +1 more source

Efficacy and safety of rimegepant for the acute treatment of migraine in Black or African American adults: A post hoc pooled subgroup analysis from three randomized, placebo‐controlled clinical trials

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective This post hoc subgroup analysis was conducted using pooled data from three US‐based clinical trials to compare efficacy and safety of rimegepant 75 mg versus placebo in acute migraine in adults who are Black or African American.
Larry Charleston IV, Cynthia E. Armand, Teshamae S. Monteith, Hope L. O'Brien, Chandra C. Abbott, Glenn C. Pixton, Terence Fullerton   +6 more
wiley   +1 more source

‘Living Well With a PICC at Home’: Co‐Design and Evaluation of a Peripherally Inserted Central Catheter (PICC) Booklet

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To co‐design an information booklet to support adults living with a peripherally inserted central catheter (PICC) at home. Design A sequential, mixed‐method approach using Boyd's co‐design framework. Method A diverse project team led co‐design of a PICC booklet based on preferences and PICC management strategies identified through content ...
Rebecca Sharp, Qunyan Xu, Robyn Pumpa, Nadia Corsini, Julie Marker, Jodie Altschwager, Alanna Ortmann, Lisa Turner, Lili Jin, Amanda Ullman, Adrian Esterman   +10 more
wiley   +1 more source