Results 101 to 110 of about 88,386 (325)

Tissue oxygenation dynamics during transition from seizure to spreading depolarization in rat brain

Epilepsia, EarlyView.
Abstract Objective Spreading depolarization (SD) is a phenomenon underlying various neurological conditions, including epilepsy. Researchers have suspected that local tissue oxygenation breakdown induces spontaneous SD. In this study, we investigated the relationship between spontaneous epileptic seizures and SD, with a focus on the role of local ...
Jiayang Liu, Bruce J. Gluckman
wiley   +1 more source

Electrically Evoked Compound Action Potentials in Spinal Cord Stimulation: Implications for Preclinical Research Models

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives The study aimed to assess the feasibility of recording electrically evoked compound action potentials (ECAPs) from the rat spinal cord. To achieve this, we characterized electrophysiological responses of dorsal column (DC) axons from electrical stimulation and quantified the relationship between ECAP and motor thresholds (ECAPTs and
Birte Elisabeth Dietz, Dave Mugan, Quoc Chi Vuong, Ilona Obara   +3 more
wiley   +1 more source

5-HT3-Receptor Antagonist Inhibits Visceral Pain Differently in Chemical and Mechanical Stimuli in Rats

Journal of Pharmacological Sciences, 2004
The present study was designed to compare the effects of a selective 5-HT3-receptor antagonist, alosetron, on the glycerol- and colorectal distention (CRD)-induced visceral nociception as measured by changes in EMG of the external oblique muscle in ...
Tomohisa Mori, Ken-ichi Kawano, Takashi Shishikura   +2 more
doaj   +1 more source

Multiparameter behavioral profiling reveals distinct thermal response regimes in Caenorhabditis elegans. [PDF]

, 2012
BackgroundResponding to noxious stimuli by invoking an appropriate escape response is critical for survival of an organism. The sensations of small and large changes in temperature in most organisms have been studied separately in the context of ...
Ghosh, Rajarshi, Kruglyak, Leonid, Mohammadi, Aylia, Ryu, William S   +3 more
core   +3 more sources

Brainstem neuroimaging of nociception and pain circuitries

PAIN Reports, 2019
The brainstem is known to be an important brain area for nociception and pain processing, and both relaying and coordinating signaling between the cerebrum, cerebellum, and spinal cord.
V. Napadow, R. Sclocco, L. Henderson
semanticscholar   +1 more source

Trendelenburg positioning with or without norepinephrine infusion for haemodynamic support in anaesthetised hypovolemic horses

Equine Veterinary Journal, EarlyView.
Abstract Background Intraoperative haemorrhage during equine anaesthesia is a rare but potentially fatal complication requiring prompt haemodynamic support. Postural manoeuvres such as Trendelenburg (TL) positioning and vasopressor support augment venous return and improve cardiac output (CO), yet their efficacy in anaesthetised hypovolemic horses ...
Vaidehi V. Paranjape, Klaus Hopster, Ismar Lutvikadic, Bernd Driessen   +3 more
wiley   +1 more source

Impaired pain sensation in mice lacking prokineticin 2

Molecular Pain, 2006
Prokineticins (PKs), consisting of PK1 and PK2, are a pair of newly identified regulatory peptides. Two closely related G-protein coupled receptors, PKR1 and PKR2, mediate the signaling of PKs. PKs/PKRs participate in the regulation of diverse biological
Amadesi Silvia, Luo Z David, Li Jia-Da, Zhang Chengkang, Hu Wang-Ping, Bunnett Nigel, Zhou Qun-Yong   +6 more
doaj   +1 more source

Evaluation of magnetic resonance imaging guidelines for differentiation between thoracolumbar intervertebral disk extrusions and intervertebral disk protrusions in dogs [PDF]

, 2016
Four MRI variables have recently been suggested to be independently associated with a diagnosis of thoracolumbar intervertebral disk extrusion or protrusion.
Aikawa, Aikawa, Altman, Baltzer, Bergknut, Bergknut, Berknut, Besalti, Bos, Bray, Brisson, Brisson, Cihangiroglu, Cudia, da Costa, Decker, Decker, Decker, Downes, Fenn, Fisher, Flegel, Fleis, Gomes, Griffiths, Hansen, Knight, Landis, Lee, Macias, McKee, Modic, Moissonnier, Olby, Olby, Petersen, Rehman, Rihn, Robertson, Ruddle, Salger, Sander, Seiler, Sim, Smolders, Solgaard Sorensen, Song, Truszczyńska, Wie   +48 more
core   +1 more source

Controlling attention to nociceptive stimuli with working memory [PDF]

, 2011
Background: Because pain often signals the occurrence of potential tissue damage, a nociceptive stimulus has the capacity to involuntarily capture attention and take priority over other sensory inputs.
Legrain, Valéry, Crombez, Geert, Mouraux, Andre   +2 more
core   +2 more sources

Research progress on the depth of anesthesia monitoring based on the electroencephalogram

Ibrain, Volume 11, Issue 1, Page 32-43, Spring 2025.
Electroencephalogram (EEG) can noninvasive, continuous, and real‐time monitor the state of brain electrical activity, and the monitoring of EEG can reflect changes in the depth of anesthesia (DOA). The development of artificial intelligence can enable anesthesiologists to extract, analyze, and quantify DOA from complex EEG data.
Xiaolan He, Tingting Li, Xiao Wang
wiley   +1 more source