Results 121 to 130 of about 44,443 (273)
British Journal of Pharmacology, EarlyView.The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan +3 more
wiley +1 more source
Non-invasive monitoring of nociception under general anesthesia by pupillometry
, 2021 Le monitorage de la nociception est l'un des défis actuels en anesthésie. L'objectif final du développement de ce monitorage est d'administrer pour chaque patient, à chaque étape de la chirurgie, la juste dose d'analgésiques.
Sabourdin, Nada
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European Journal of Dental Education, EarlyView.ABSTRACT Introduction The aim of this paper is to assess the prevalence, impact, and understanding of Lower Back Pain (LBP) amongst final year dental students to inform the development of a module in the dental curriculum. LBP has a significant impact on the dental workforce; yet little is reported about the profession's knowledge, or the necessity for
Samuel Cope +3 more
wiley +1 more source
Neuroimmune alterations and nociceptive behavior in oral carcinogenesis in rats
European Journal of Oral Sciences, EarlyView.Abstract Oral cancer pain is a frequent and debilitating symptom associated with tumor progression. Although neuronal mechanisms have been extensively studied, the role of immune and glial cells in the trigeminal nociceptive pathway remains poorly understood.
Joana Maria dos Santos Alves +7 more
wiley +1 more source
The FEBS Journal, EarlyView.Using 1H NMR metabolomics, we measured polar and lipid metabolites from human blood neutrophils from people with frailty (n = 31, mean age 84Y), people with rheumatoid arthritis (n = 16, mean age 55Y), robust older (n = 24, mean age 66Y) and healthy younger people (n = 21, mean age 22Y).
Genna Ali Abdullah +5 more
wiley +1 more source
MODULATION OF NOCICEPTION BY BRAINSTEM NORADRENERGIC NEURONS.
, 1984 MODULATION OF NOCICEPTION BY BRAINSTEM NORADRENERGIC ...
JACQUELINE. SAGEN (7981493)
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The Role of Neuropeptide Y in Dental Pulp: Balancing Neurogenic Inflammation and Pain Modulation
International Endodontic Journal, EarlyView.ABSTRACT Background Dental pulp is a densely innervated, low‐compliance tissue in which neurogenic inflammation can rapidly escalate into oedema, raised intrapulpal pressure, microvascular compromise, and pain. While Substance P (SP) and Calcitonin gene‐related peptide (CGRP) are well‐established drivers of pulp vasodilation, the Neuroopeptide Y (NPY ...
Javier Caviedes‐Bucheli +3 more
wiley +1 more source
Basic and Clinical Neuroscience, 2020 Introduction: Broad neural circuits originate from the hypothalamic arcuate nucleus and project to many parts of the brain which are related to pain perception. Insulin receptors are found in the arcuate nucleus. Since nociception may be affected in type
Hossein Khaleghzadeh-Ahangar +4 more
doaj
Activated Microglia in Nociception
Pain Physician, 2010 Microglial cells appear to play a vital role in the initiation of certain neuropathic pain states. In order to initiate neuropathic pain, microglia need to be activated. Microglia activation in the spinal cord involves both hypertrophy as well as hyperplasia, progressing through a hypertrophic morphology, with thickened and retracted processes ...
openaire +2 more sources
Midbrain periaqueductal grey modulation of trigeminal nociception: Relationship to migraine [PDF]
, 2002 Clinical evidence suggests that the midbrain periaqueductal grey (PAG) may play a major role in the headache component of migraine. Genetic studies indicate that migraine may be a calcium channelopathy, but it is unknown in which parts of the brain the ...
Knight, Yolande Edna
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