Results 111 to 120 of about 88,386 (325)

Does nociception monitor-guided anesthesia affect opioid consumption? A systematic review of randomized controlled trials

open access: yesJournal of clinical monitoring and computing, 2019
Monitors that estimate nociception during anesthesia may be used to guide opioid and other analgesics administration to optimize anesthesia care and possibly outcome.
Fleur S. Meijer   +9 more
semanticscholar   +1 more source

Things We Do for No Reason™: Prescribing gabapentinoids for pain

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Gabapentin and pregabalin are among the most frequently prescribed medications in the United States, with gabapentin in the top 10 and pregabalin in the top 100. Despite FDA approval for only select neuropathic conditions, most use is for off‐label pain indications.
Niti G. Patel   +4 more
wiley   +1 more source

PACAP and migraine headache: immunomodulation of neural circuits in autonomic ganglia and brain parenchyma. [PDF]

open access: yes, 2018
The discovery that intravenous (IV) infusions of the neuropeptide PACAP-38 (pituitary adenylyl cyclase activating peptide-38) induced delayed migraine-like headaches in a large majority of migraine patients has resulted in considerable excitement in ...
Akerman, Simon   +2 more
core   +2 more sources

Types of Pain in Multiple System Atrophy

open access: yesMovement Disorders, EarlyView.
Abstract Background Pain affects up to 87% of people with multiple system atrophy (MSA), but it remains unclear which types of pain contribute most to the overall burden. Objective To estimate the frequency of different types of pain in MSA individuals.
Nicole Campese   +19 more
wiley   +1 more source

What Role Does the Central Nervous System Play in Refractory LUTS, and What Are the Therapeutic Implications? ICI‐RS 2025

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Aims While many patients with lower urinary tract symptoms (LUTS) improve by treating peripheral causes, a substantial proportion continue to experience symptoms despite apparently successful interventions. Central nervous system (CNS) mechanisms could potentially contribute to persisting symptoms after the initial peripheral cause has been ...
Mathijs M. de Rijk   +7 more
wiley   +1 more source

Methods Used to Evaluate Pain Behaviors in Rodents

open access: yesFrontiers in Molecular Neuroscience, 2017
Rodents are commonly used to study the pathophysiological mechanisms of pain as studies in humans may be difficult to perform and ethically limited.
Jennifer R. Deuis   +3 more
doaj   +1 more source

Peripheral Mediators of Colorectal Nociception and Sensitization [PDF]

open access: yes, 2012
Several ion channels are thought to facilitate colorectal afferent neuron sensitization, which contributes to abdominal pain in irritable bowel syndrome (IBS).
Kiyatkin, Michael E
core  

Developing a Pediatric Pain Curriculum for Pediatric Anesthesia Fellows in Sub‐Saharan Africa: A Delphi Study

open access: yesPediatric Anesthesia, EarlyView.
ABSTRACT Background Comprehensive pain management in children requires a specialized skillset, with a limited number of clinicians possessing the level of expertise required to successfully navigate the complexities of holistic care. The emergence of pediatric anesthesia fellowship programs in sub‐Saharan Africa presents an opportunity to embed a ...
Anisa Bhettay   +24 more
wiley   +1 more source

The Effect of Melatonin on Behavioral, Molecular, and Histopathological Changes in Cuprizone Model of Demyelination [PDF]

open access: yes, 2016
Multiple sclerosis (MS) is an autoimmune, demyelinating disease of the central nervous system. The protective effects of melatonin (MLT) on various neurodegenerative diseases, including MS, have been suggested.
Ghadiri, T.   +6 more
core  

Cutaneous nociception: Role of keratinocytes

open access: yesExperimental Dermatology, 2019
Recent years have brought an enhanced understanding of keratinocyte contribution to cutaneous nociception. While intra‐epidermal nerve endings were classically considered as the exclusive transducers of cutaneous noxious stimuli, it has now been ...
M. Talagas   +3 more
semanticscholar   +1 more source

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