Results 111 to 120 of about 88,386 (325)
Monitors that estimate nociception during anesthesia may be used to guide opioid and other analgesics administration to optimize anesthesia care and possibly outcome.
Fleur S. Meijer +9 more
semanticscholar +1 more source
Things We Do for No Reason™: Prescribing gabapentinoids for pain
Abstract Gabapentin and pregabalin are among the most frequently prescribed medications in the United States, with gabapentin in the top 10 and pregabalin in the top 100. Despite FDA approval for only select neuropathic conditions, most use is for off‐label pain indications.
Niti G. Patel +4 more
wiley +1 more source
PACAP and migraine headache: immunomodulation of neural circuits in autonomic ganglia and brain parenchyma. [PDF]
The discovery that intravenous (IV) infusions of the neuropeptide PACAP-38 (pituitary adenylyl cyclase activating peptide-38) induced delayed migraine-like headaches in a large majority of migraine patients has resulted in considerable excitement in ...
Akerman, Simon +2 more
core +2 more sources
Types of Pain in Multiple System Atrophy
Abstract Background Pain affects up to 87% of people with multiple system atrophy (MSA), but it remains unclear which types of pain contribute most to the overall burden. Objective To estimate the frequency of different types of pain in MSA individuals.
Nicole Campese +19 more
wiley +1 more source
ABSTRACT Aims While many patients with lower urinary tract symptoms (LUTS) improve by treating peripheral causes, a substantial proportion continue to experience symptoms despite apparently successful interventions. Central nervous system (CNS) mechanisms could potentially contribute to persisting symptoms after the initial peripheral cause has been ...
Mathijs M. de Rijk +7 more
wiley +1 more source
Methods Used to Evaluate Pain Behaviors in Rodents
Rodents are commonly used to study the pathophysiological mechanisms of pain as studies in humans may be difficult to perform and ethically limited.
Jennifer R. Deuis +3 more
doaj +1 more source
Peripheral Mediators of Colorectal Nociception and Sensitization [PDF]
Several ion channels are thought to facilitate colorectal afferent neuron sensitization, which contributes to abdominal pain in irritable bowel syndrome (IBS).
Kiyatkin, Michael E
core
ABSTRACT Background Comprehensive pain management in children requires a specialized skillset, with a limited number of clinicians possessing the level of expertise required to successfully navigate the complexities of holistic care. The emergence of pediatric anesthesia fellowship programs in sub‐Saharan Africa presents an opportunity to embed a ...
Anisa Bhettay +24 more
wiley +1 more source
The Effect of Melatonin on Behavioral, Molecular, and Histopathological Changes in Cuprizone Model of Demyelination [PDF]
Multiple sclerosis (MS) is an autoimmune, demyelinating disease of the central nervous system. The protective effects of melatonin (MLT) on various neurodegenerative diseases, including MS, have been suggested.
Ghadiri, T. +6 more
core
Cutaneous nociception: Role of keratinocytes
Recent years have brought an enhanced understanding of keratinocyte contribution to cutaneous nociception. While intra‐epidermal nerve endings were classically considered as the exclusive transducers of cutaneous noxious stimuli, it has now been ...
M. Talagas +3 more
semanticscholar +1 more source

