Results 11 to 20 of about 14,156 (228)

INDEX OF ANALGESIA-NOCICEPTION: OPPORTUNITIES AND LIMITS

open access: yesВестник анестезиологии и реаниматологии, 2017
The review includes clinical opportunities of the new technique for evaluation balance of nociception/anti-nociception with help of medication of ANI-Monitor (MetroDoloris®, France), used abroad, with the calculation of original index of analgesia ...
A. P. Spasova   +2 more
doaj   +2 more sources

The ankyrin repeat domain of the TRPA protein painless is important for thermal nociception but not mechanical nociception. [PDF]

open access: yesPLoS ONE, 2012
The Drosophila TRPA channel Painless is required for the function of polymodal nociceptors which detect noxious heat and noxious mechanical stimuli. These functions of Painless are reminiscent of mammalian TRPA channels that have also been implicated in ...
Richard Y Hwang   +2 more
doaj   +2 more sources

Nociceptor-Enriched Genes Required for Normal Thermal Nociception [PDF]

open access: yesCell Reports, 2016
Here, we describe a targeted reverse genetic screen for thermal nociception genes in Drosophila larvae. Using laser capture microdissection and microarray analyses of nociceptive and non-nociceptive neurons, we identified 275 nociceptor-enriched genes ...
Ken Honjo   +4 more
doaj   +4 more sources

Daily rhythm of nociception in rats [PDF]

open access: yesJournal of Circadian Rhythms, 2004
Background Many behavioral and physiological variables exhibit daily rhythmicity. Few investigations of the daily rhythmicity in nociception have been conducted, and conflicting results have been obtained.
Jayaprakash S   +4 more
doaj   +2 more sources

Analgesia Nociception Index for perioperative analgesia monitoring in spinal surgery [PDF]

open access: yesRevista Brasileira de Anestesiologia, 2016
Background and objectives: The Analgesia Nociception Index is an index used to measure the levels of pain, sympathetic system activity and heart rate variability during general anesthesia.
Guldem Turan   +6 more
doaj   +2 more sources

Descending control of nociception in insects? [PDF]

open access: yes, 2022
Modulation of nociception allows animals to optimize chances of survival by adapting their behaviour in different contexts. In mammals, this is executed by neurons from the brain and is referred to as the descending control of nociception.
Sarlak, Sajedeh   +8 more
core   +1 more source

The role of cGMP and PKG-I in spinal nociceptive processing [PDF]

open access: yes, 2005
First paragraph (this article has no abstract) Persistent stimulation of nociceptors results in sensitization of nociceptive sensory neurons, which is associated with hyperalgesia and allodynia.
Geisslinger, Gerd   +11 more
core   +1 more source

Distinct transcriptional responses of mouse sensory neurons in models of human chronic pain conditions [version 1; referees: 2 approved]

open access: yesWellcome Open Research, 2018
Background: Sensory neurons play an essential role in almost all pain conditions, and have recently been classified into distinct subsets on the basis of their transcriptomes. Here we have analysed alterations in dorsal root ganglia (DRG) gene expression
M.A. Bangash   +17 more
doaj   +1 more source

P/Q-type calcium-channel blockade in the periaqueductal gray facilitates trigeminal nociception: a functional genetic link for migraine? [PDF]

open access: yes, 2002
The discovery of mis-sense mutations in the alpha1A subunit of the P/Q-type calcium channel in patients with familial hemiplegic migraine indicates the potential involvement of dysfunctional ion channels in migraine.
Goadsby, PJ   +11 more
core   +1 more source

Leptin and fractalkine: novel subcutaneous cytokines in burn injury

open access: yesDisease Models & Mechanisms, 2020
Burn injury is a pathology underpinned by progressive and aberrant inflammation. It is a major clinical challenge to survival and quality of life. Although the complex local and disseminating pathological processes of a burn injury ultimately stem from ...
Dominic Friston   +7 more
doaj   +1 more source

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