Results 31 to 40 of about 88,386 (325)
Wellcome Open Research, 2018 Background: Functional deletion of the Scn9a (sodium voltage-gated channel alpha subunit 9) gene encoding sodium channel Nav1.7 makes humans and mice pain-free. Opioid signalling contributes to this analgesic state.
Vanessa Pereira +5 more
doaj +1 more source
Comparison of the qCON and qNOX indices for the assessment of unconsciousness level and noxious stimulation response during surgery [PDF]
, 2016 The objective of this work is to compare the performances of two electroencephalogram based indices for detecting loss of consciousness and loss of response to nociceptive stimulation.
Agustí, Mercé +8 more
core +2 more sources
KCNQ Channels in the Mesolimbic Reward Circuit Regulate Nociception in Chronic Pain in Mice
Neuroscience Bulletin, 2021 Mesocorticolimbic dopaminergic (DA) neurons have been implicated in regulating nociception in chronic pain, yet the mechanisms are barely understood.
Hao-Ran Wang +11 more
semanticscholar +1 more source
Comparison of clinical signs and outcomes between dogs with presumptive ischemic myelopathy and dogs with acute non compressive nucleus pulposus extrusion [PDF]
, 2016 OBJECTIVE To compare clinical signs and outcomes between dogs with presumptive ischemic myelopathy and dogs with presumptive acute noncompressive nucleus pulposus extrusion (ANNPE). DESIGN Retrospective study. ANIMALS 51 dogs with ischemic myelopathy and
De Decker, S +3 more
core +3 more sources
Ingested bovine amniotic fluid enhances morphine antinociception in rats [PDF]
, 2000 Ingestion by rats of rat placenta or amniotic fluid enhances opioid-mediated, or partly opioid-mediated, antinociception produced by morphine injection, vaginal or cervical stimulation, late pregnancy, and foot shock.
Corpening, James W. +2 more
core +1 more source
Molecular Pain, 2015 Background Trigeminal neuralgia is accompanied by severe mechanical, thermal and chemical hypersensitivity of the orofacial area innervated by neurons of trigeminal ganglion (TG).
Ana Paula Lulz +3 more
doaj +1 more source
Changes in Activity of the Same Thalamic Neurons to Repeated Nociception in Behaving Mice. [PDF]
PLoS ONE, 2015 The sensory thalamus has been reported to play a key role in central pain sensory modulation and processing, but its response to repeated nociception at thalamic level is not well known.
Yeowool Huh, Jeiwon Cho
doaj +1 more source
A novel multivariate STeady-state index during general ANesthesia (STAN) [PDF]
, 2017 The assessment of the adequacy of general anesthesia for surgery, namely the nociception/anti-nociception balance, has received wide attention from the scientific community. Monitoring systems based on the frontal EEG/EMG, or autonomic state reactions (e.
A Albertin +34 more
core +1 more source
PLoS Neglected Tropical Diseases, 2023 Scorpion sting envenomations (SSE) are feared by the intense pain that they produce in victims. Pain from SSE is triggered mainly by the presence of neurotoxins in the scorpion venom that modulates voltage-gated ion channels.
Felipe Cerni +8 more
doaj +2 more sources
Nature Communications, 2022 The processing of nociception in the somatosensory cortex (S1) has yet to be fully understood. Here, the authors demonstrate that the dysgranular region in S1 has an affinity for nociception and is critically involved in pain-like behavior.
Hironobu Osaki +3 more
doaj +1 more source