Results 21 to 30 of about 2,763 (207)
PLoS Neglected Tropical Diseases, 2023 Scorpion sting envenomations (SSE) are feared by the intense pain that they produce in victims. Pain from SSE is triggered mainly by the presence of neurotoxins in the scorpion venom that modulates voltage-gated ion channels.
Felipe Cerni +8 more
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ATF4 selectively regulates heat nociception and contributes to kinesin-mediated TRPM3 trafficking
Nature Communications, 2021 The molecular mechanisms mediating nociception are unclear. Here, the authors show that the Activating Transcription Factor 4 (ATF4) is important for the response to heat nociception in mice and ATF4 role in mediating protein trafficking in dorsal root ...
Man-Xiu Xie +10 more
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INDEX OF ANALGESIA-NOCICEPTION: OPPORTUNITIES AND LIMITS
Вестник анестезиологии и реаниматологии, 2017 The review includes clinical opportunities of the new technique for evaluation balance of nociception/anti-nociception with help of medication of ANI-Monitor (MetroDoloris®, France), used abroad, with the calculation of original index of analgesia ...
A. P. Spasova +2 more
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The validity and applications of the analgesia nociception index: a narrative review
Frontiers in Surgery, 2023 Pain refers to the subjective, unpleasant experience that is related to illness or injury. In contrast to pain, nociception refers to the physiological neural processing of noxious stimuli, such as intra-operative surgical stimuli.
Bill Hum +5 more
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Analgesic targets identified in mouse sensory neuron somata and terminal pain translatomes
Cell ReportsSummary: The relationship between transcription and protein expression is complex. We identified polysome-associated RNA transcripts in the somata and central terminals of mouse sensory neurons in control, painful (plus nerve growth factor), and pain ...
M. Ali Bangash +12 more
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Do decapod crustaceans have nociceptors for extreme pH? [PDF]
PLoS ONE, 2010 Nociception is the physiological detection of noxious stimuli. Because of its obvious importance, nociception is expected to be widespread across animal taxa and to trigger robust behaviours reliably. Nociception in invertebrates, such as crustaceans, is
Sakshi Puri, Zen Faulkes
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The Neurobiology of Nociceptive and Anti-nociceptive Systems
Pain Physician, 2005 Pain is both a sensory event of the peripheral and central nervous systems and an experience that arises from, and reciprocally can affect processes of higher consciousness. Alterations in peripheral and central neuraxes can lead to sensitization, structural modification and long-term potentiation that can overcome modulatory influence(s) and change ...
openaire +2 more sources
Frontiers in Medicine, 2022 BackgroundNociception monitors are being increasingly used during surgery, but their effectiveness in guiding intraoperative opioid administration is still uncertain.
Dandan Ma +6 more
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PAIN Reports. Introduction:. The nuclear mitogen- and stress-activated kinases (MSKs) play a critical role in the development and persistence of pain after tissue injury. Objectives:. Here, we ascertained the MSK isoform, the cells and mechanisms, which mediate MSKs'
Jahanzaib Irfan +11 more
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Bulletin of Pharmaceutical Sciences. Assiut UniversityDiabetic neuropathy (DN) is one of the complications of diabetes mellitus. In the present study, melatonin’s antinociceptive effect in DN was evaluated by studying its action on the expression of the transient receptor potential vanilloid 1 channel gene (
Ehab El-Desoky +9 more
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