Results 41 to 50 of about 88,386 (325)
An interleukin-33/ST2 signaling deficiency reduces overt pain-like behaviors in mice [PDF]
, 2013 Interleukin (IL)-33, the most recent member of the IL family of cytokines, signals through the ST2 receptor. IL-33/ST2 signaling mediates antigen challenge-induced mechanical hyperalgesia in the joints and cutaneous tissues of immunized mice. The present
Alves-Filho, J.C. +9 more
core +3 more sources
ATF4 selectively regulates heat nociception and contributes to kinesin-mediated TRPM3 trafficking
Nature Communications, 2021 The molecular mechanisms mediating nociception are unclear. Here, the authors show that the Activating Transcription Factor 4 (ATF4) is important for the response to heat nociception in mice and ATF4 role in mediating protein trafficking in dorsal root ...
Man-Xiu Xie +10 more
doaj +1 more source
INDEX OF ANALGESIA-NOCICEPTION: OPPORTUNITIES AND LIMITS
Вестник анестезиологии и реаниматологии, 2017 The review includes clinical opportunities of the new technique for evaluation balance of nociception/anti-nociception with help of medication of ANI-Monitor (MetroDoloris®, France), used abroad, with the calculation of original index of analgesia ...
A. P. Spasova +2 more
doaj +1 more source
The validity and applications of the analgesia nociception index: a narrative review
Frontiers in Surgery, 2023 Pain refers to the subjective, unpleasant experience that is related to illness or injury. In contrast to pain, nociception refers to the physiological neural processing of noxious stimuli, such as intra-operative surgical stimuli.
Bill Hum +5 more
doaj +1 more source
, 2017 Pain is an integrative phenomenon that results from dynamic interactions between sensory and contextual (i.e., cognitive, emotional, and motivational) processes.
Gross, Joachim +2 more
core +1 more source
Mechanisms of microbial–neuronal interactions in pain and nociception
Neurobiology of Pain, 2020 Highlights • Molecular mechanisms of how microorganisms communicate with sensory afferent neurons.• How pathogenic microorganisms directly communicate with nociceptor neurons to inflict pain on the host.• Symbiotic bacterial communication with gut ...
Valentina N. Lagomarsino +2 more
semanticscholar +1 more source
, 2016 Experiments of pain with human subjects are difficult, subjective, and ethically constrained. Since the molecular mechanisms of pain transduction are reasonably conserved among different species, these problems are partially solved by the use of animal ...
Leung, Kawai +3 more
core +2 more sources
TRP Channel Cooperation for Nociception: Therapeutic Opportunities.
Annual Review of Pharmacology and Toxicology, 2020 Chronic pain treatment remains a sore challenge, and in our aging society, the number of patients reporting inadequate pain relief continues to grow. Current treatment options all have their drawbacks, including limited efficacy and the propensity of ...
Dorien Bamps +3 more
semanticscholar +1 more source
Do decapod crustaceans have nociceptors for extreme pH? [PDF]
PLoS ONE, 2010 Nociception is the physiological detection of noxious stimuli. Because of its obvious importance, nociception is expected to be widespread across animal taxa and to trigger robust behaviours reliably. Nociception in invertebrates, such as crustaceans, is
Sakshi Puri, Zen Faulkes
doaj +1 more source
Analgesic targets identified in mouse sensory neuron somata and terminal pain translatomes
Cell ReportsSummary: The relationship between transcription and protein expression is complex. We identified polysome-associated RNA transcripts in the somata and central terminals of mouse sensory neurons in control, painful (plus nerve growth factor), and pain ...
M. Ali Bangash +12 more
doaj +1 more source