Results 61 to 70 of about 2,763 (207)
Effect of Spinally Administered Simvastatin on the Formalin-Induced Nociceptive Response in Mice
Journal of Pharmacological Sciences, 2012 Clinical and experimental observations indicated that 3-hydroxy-3-methylglutaryl CoA reductase inhibitor statins have pleiotropic effects. The present study determined the antinociceptive property of centrally administered simvastatin on the formalin ...
Masahiro Ohsawa +4 more
doaj +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background Intraoperative haemorrhage during equine anaesthesia is a rare but potentially fatal complication requiring prompt haemodynamic support. Postural manoeuvres such as Trendelenburg (TL) positioning and vasopressor support augment venous return and improve cardiac output (CO), yet their efficacy in anaesthetised hypovolemic horses ...
Vaidehi V. Paranjape +3 more
wiley +1 more source
Journal of Pharmacological Sciences, 2004 The present study was designed to compare the effects of a selective 5-HT3-receptor antagonist, alosetron, on the glycerol- and colorectal distention (CRD)-induced visceral nociception as measured by changes in EMG of the external oblique muscle in ...
Tomohisa Mori +2 more
doaj +1 more source
Research progress on the depth of anesthesia monitoring based on the electroencephalogram
Ibrain, Volume 11, Issue 1, Page 32-43, Spring 2025.Electroencephalogram (EEG) can noninvasive, continuous, and real‐time monitor the state of brain electrical activity, and the monitoring of EEG can reflect changes in the depth of anesthesia (DOA). The development of artificial intelligence can enable anesthesiologists to extract, analyze, and quantify DOA from complex EEG data.
Xiaolan He, Tingting Li, Xiao Wang
wiley +1 more source
International Journal of Cancer, EarlyView.ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari +10 more
wiley +1 more source
Lasers in Surgery and Medicine, EarlyView.ABSTRACT Objectives This retrospective study evaluated the clinical outcomes associated with a photobiomodulation therapy (PBMT) protocol in patients with inferior alveolar nerve (IAN) injury following oral and maxillofacial surgery. The study specifically investigated whether the etiology of paresthesia, the time elapsed before treatment initiation ...
Halenur Ates, Yavuz Tolga Korkmaz
wiley +1 more source
Methods Used to Evaluate Pain Behaviors in Rodents
Frontiers in Molecular Neuroscience, 2017 Rodents are commonly used to study the pathophysiological mechanisms of pain as studies in humans may be difficult to perform and ethically limited.
Jennifer R. Deuis +3 more
doaj +1 more source
Movement Disorders Clinical Practice, EarlyView.Abstract Background Variants in AFG3‐Like Matrix AAA Peptidase, Subunit 2 (AFG3L2) gene are associated with diverse clinical phenotypes. Here, we describe phenotypic findings of two unrelated children with de novo heterozygous variant and one family with inherited heterozygous variant in AFG3L2 gene.
Sangeetha Yoganathan +14 more
wiley +1 more source
Impaired pain sensation in mice lacking prokineticin 2
Molecular Pain, 2006 Prokineticins (PKs), consisting of PK1 and PK2, are a pair of newly identified regulatory peptides. Two closely related G-protein coupled receptors, PKR1 and PKR2, mediate the signaling of PKs. PKs/PKRs participate in the regulation of diverse biological
Amadesi Silvia +6 more
doaj +1 more source
PM&R, EarlyView.Abstract Objective The aim of this systematic review and meta‐analysis is to determine the effects of transcranial direct current stimulation (TDCS) on pain (considering the different types of pain measured) and function in adults with knee osteoarthritis (OA).
Noemí Moreno‐Segura +4 more
wiley +1 more source