Results 201 to 210 of about 88,386 (325)

Protocol for modulating anesthesia delta oscillations using closed loop auditory stimulation. [PDF]

Front Hum Neurosci
Pic Roca C, Bazregarzadeh H, Morisson L, Martin A, Verdonck O, Gibbs S, Lina JM, Carrier J, Richebé P, Duclos C.   +9 more
europepmc   +1 more source

Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy

Journal of Biomedical Materials Research Part A, Volume 114, Issue 5, May 2026.
Macrophage‐Targeting Biomaterials for Osteoarthritis Therapy. Created in BioRender. Jain, E. (2026) https://BioRender.com/x4f9o8g. ABSTRACT Osteoarthritis (OA) is a highly prevalent, disabling, and painful disease of the joints, characterized by progressive cartilage degeneration, synovial fibrosis, and pain.
Era Jain, Paul Nana Kwame Sagoe
wiley   +1 more source

Identification of molecular nociceptors in Octopus vulgaris through functional characterisation in Caenorhabditis elegans. [PDF]

Biol Open
Pieroni EM, O'Connor V, Holden-Dye L, Imperadore P, Fiorito G, Dillon J.   +5 more
europepmc   +1 more source

Liver Gene Therapy in Fabry Disease Mice With Low Doses of rAAV2/8 Expressing a Codon‐Optimized hGLA cDNA Results in Long‐Term Disease Correction

Journal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
AAV‐mediated gene therapy targets the liver to produce and secrete into circulation functional α‐Gal A, which is taken up by tissues to reduce glycosphingolipid accumulation and prevent disease progression in juvenile Fabry mice, even at low AAV doses. ABSTRACT Fabry disease (FD) is an X‐linked lysosomal storage disorder caused by mutations in the GLA ...
Himanshi Saxena, Rossana Domenis, Giulia Romano, Jessica Biasizzo, Martina Ferro, Dania Ferino, Antonio Vicidomini, Alessandra Iaconcig, Giulia Bortolussi, Lorena Zentilin, Andrea Dardis, Andrés F. Muro   +11 more
wiley   +1 more source

Current Trends in Anaesthesia Monitoring: A Survey Study. [PDF]

Turk J Anaesthesiol Reanim
Söğüt MS, Sincer Y, Mendeş E, Gürkan Y.   +3 more
europepmc   +1 more source

Chronic Pain: Epidemiology, Pathophysiology, and Clinical Management

MedComm, Volume 7, Issue 5, May 2026.
The multidimensional nature of chronic pain is illustrated through four interconnected domains. (Left) Epidemiology and Global Burden: Chronic pain affects approximately one in five individuals globally, contributing to a rising trend in disability‐adjusted life years (YLDs) and a significant socioeconomic impact.
Zhihao Shang, Zijiao Tian, Zhaoquan Wang, Zerui Yang, Ziyao Wang, Zikang Wang, Ziqing Wang, Xingyuan He, Yu Yan, Yuanfeng Gong, Siyuan Xu, Xinyi Li, Guihua Tian   +12 more
wiley   +1 more source

Influence of qNOX-guided remifentanil titration on intraoperative dosing and postoperative pain in total knee arthroplasty: a pilot randomized trial. [PDF]

J Anesth Analg Crit Care
Liu F, Wang E, Huang B, Yang D, Gao X.
europepmc   +1 more source

Cardiopulmonary arrest following extradural analgesia and suspected secondary sympathetic blockade in a critically ill dog

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract An 8‐year‐old, male, entire Cocker Spaniel presented to the Queen Mother Hospital for Animals for treatment of an iatrogenic septic uroabdomen secondary to traumatic urinary catheterisation. After initial stabilisation, it underwent diagnostic imaging and definitive surgical correction comprising a cystotomy and bladder reconstruction.
Joe Simon, Manuel Enrique Herrera‐Linares, Hannah Louise Matson, Cristina Bianchi   +3 more
wiley   +1 more source

Objective monitoring of acute pain and nociception in anaesthesia and intensive care: evidence and applications. [PDF]

Anaesthesiol Intensive Ther
Danel JK, Rosada-Kurasinska J, Copik MM, Zdanowski S, Gola W, Misiołek H, Bartkowska-Śniatkowska A, Białka S.   +7 more
europepmc   +1 more source

SIRT1 Downregulation by Advanced Glycation End Products Activates RANKL‐Dependent Osteoclast Signaling and Drives Chondrocyte Senescence During Osteoarthritis Development

Aging Cell, Volume 25, Issue 5, May 2026.
Mechanistic study of AGEs‐induced OA progression via SIRT1/RANKL/RANK signaling‐mediated osteoclast–chondrocyte communication and cellular senescence. ABSTRACT Advanced glycation end products (AGEs) accumulate with aging and metabolic stress and are increasingly implicated in osteoarthritis (OA) pathology.
Yizhou Li, Jian Wu, Rui Liu, Qiang Li, Fei Xue   +4 more
wiley   +1 more source