Results 181 to 190 of about 88,386 (325)

The para^bss1 Drosophila melanogaster as Model for Chronic Nociception: Insights Into Cannabidiol Analgesic Effects. [PDF]

Eur J Pain
Malta SM, Correia LIV, Marquez AS, Bernardes LMM, Howland JG, Mendes-Silva AP, Espíndola FS, Ueira-Vieira C.   +7 more
europepmc   +1 more source

Hypoxia‐induced vulnerability of the somatosensory nervous system

The Journal of Physiology, EarlyView.
Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
wiley   +1 more source

Comparative Physiology of Nociception and Pain.

Physiology, 2018
L. Sneddon
semanticscholar   +1 more source

Drafting the calmodulation playbook: Emerging structural insights into transient receptor potential channel regulation by calmodulin

The Journal of Physiology, EarlyView.
Abstract figure legend Calmodulin (CaM) is a ubiquitous calcium (Ca2+) sensor that translates intracellular Ca2+ signals into modulation of hundreds of effector proteins including ion channels. CaM is increasingly recognized as a key regulator of the transient receptor potential (TRP) channel family, yet the underlying ‘calmodulation playbook’ is only ...
Aden M. Alemayhu, Candice E. Paulsen
wiley   +1 more source

TMJ hyperextension is associated with sustained nociception and dysfunction of pain modulation pathways in female rats. [PDF]

Cranio
Scharnhorst M, Aardema Faigh D, Escaldi A, Zhang L, Kirkwood KL, Ohrbach R, Durham PL.   +6 more
europepmc   +1 more source

Sentience in cephalopod molluscs: an updated assessment

Biological Reviews, Volume 101, Issue 3, Page 1311-1333, June 2026.
ABSTRACT This article evaluates the evidence for sentience – the capacity to have feelings – in cephalopod molluscs: octopus, cuttlefish, squid, and nautilus. Our framework includes eight criteria, covering both whether the animal's nervous system could support sentience and whether their behaviour indicates sentience.
Alexandra K. Schnell, Heather Browning, Andrew Crump, Charlotte C. Burn, Jonathan Birch   +4 more
wiley   +1 more source

Justifying model complexity: Evaluating transfer learning against classical models for intraoperative nociception monitoring under anesthesia. [PDF]

PLoS One
Lee C, Lee J, Vogt KA, Munshi M.
europepmc   +1 more source

Neurosteroids in pain management: A new perspective on an old player [PDF]

, 2018
Covey, Douglas F, Jevtovic-Todorovic, Vesna, Joksimovic, Sonja L, Todorovic, Slobodan M   +3 more
core   +2 more sources

The Recycling Endosomal (Na+, K+)/H+ Exchanger NHE6/SLC9A6 Facilitates Signal Transduction by Shuttling Cyclin‐Dependent Kinase 5 to the Plasma Membrane

Acta Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Aim The alkali cation/proton exchanger NHE6/SLC9A6 regulates luminal pH homeostasis and trafficking of recycling endosomes in most tissues, especially neurons. Loss‐of‐function mutations in NHE6 cause Christianson Syndrome, an X‐linked neurodevelopmental and neurodegenerative disorder; however, the underlying molecular and cellular mechanisms ...
Rebecca Flessner, Alina Ilie, Léo Han, Annie Boucher, Rebecca Anne McKinney, Reza Sharif‐Naeini, John Orlowski   +6 more
wiley   +1 more source

Effects of analgesia on the response to a noxious stimulus in Norway lobsters (Nephrops norvegicus). [PDF]

Sci Rep
Kasiouras E, Rotllant G, Gräns A, Hjelmstedt P, Sneddon LU.   +4 more
europepmc   +1 more source