Results 171 to 180 of about 44,443 (273)

The para^bss1 Drosophila melanogaster as Model for Chronic Nociception: Insights Into Cannabidiol Analgesic Effects. [PDF]

Eur J Pain
Malta SM, Correia LIV, Marquez AS, Bernardes LMM, Howland JG, Mendes-Silva AP, Espíndola FS, Ueira-Vieira C.   +7 more
europepmc   +1 more source

Integrative Assessment of Desmostachya bipinnata (L.) Root Extract: Anti‐Inflammatory and Antinociceptive Effects Supported by Molecular Docking and Network Pharmacology

Flavour and Fragrance Journal, Volume 41, Issue 4, Page 841-858, July 2026.
The ethanolic root extract of Desmostachya bipinnata exhibited significant anti‐inflammatory and antinociceptive activities in in vitro, in vivo and in silico models, revealing bioactive compounds capable of modulating key inflammatory targets and supporting the plant's traditional therapeutic potential.
Muhammad Hussnain Siddique, Muhammad Muzammil Nazir, Saima Muzammil, Iqra Farzeen, Shafaq Latif, Asma Ashraf, Jorddy Neves Cruz   +6 more
wiley   +1 more source

The nociceptor primary cilium. [PDF]

Brain
Ganter GK, Reveche HC, Fitzsimons LA, Khomula EV, Levine JD, Tucker KL.   +5 more
europepmc   +1 more source

A TRIP‐nano killer silencing the pain pacemakers

The Journal of Physiology, EarlyView.
Elisabetta Cerbai
wiley   +1 more source

Routine circumferential patellar denervation during total knee arthroplasty did not consistently eliminate neural structures at the lateral patellar border: A prospective randomised controlled trial with histological outcomes

Journal of Experimental Orthopaedics, Volume 13, Issue 3, July 2026.
Abstract Purpose Circumferential patellar denervation is widely performed during total knee arthroplasty under the assumption that electrocautery ablates nociceptive neural structures at the lateral patellar border. However, the microscopic effect of this procedure on neural substrates remains poorly defined.
Daniel Petek, Gishane Rossanaly, Alexander Frank Heimann, Julien Hirt, Grégoire Thürig, Edouard Stauffer, Joseph M. Schwab, Marc Barrera Uso   +7 more
wiley   +1 more source

From Epithelial Sensing to Visceral Pain: Neuropod and Enterochromaffin Cells in Gut Neuroepithelial Circuits. [PDF]

Int J Mol Sci
Nowacka A, Śniegocki M, Ziółkowska EA.   +2 more
europepmc   +1 more source

Effects of analgesia on the response to a noxious stimulus in Norway lobsters (Nephrops norvegicus). [PDF]

Sci Rep
Kasiouras E, Rotllant G, Gräns A, Hjelmstedt P, Sneddon LU.   +4 more
europepmc   +1 more source

Dexmedetomidine Rapidly Relieves Stress‐Induced Hyperalgesia via Presynaptic α2‐Adrenergic Inhibition at Orbitofrontal–Insular Glutamatergic Synapses

MedComm, Volume 7, Issue 7, July 2026.
This study identified a maladaptive OFC–AIC glutamatergic circuit in stress‐induced hyperalgesia induction. This critical circuit provides an α2‐AR‐dependent braking target for dexmedetomidine to alleviate excessive glutamatergic transmission and hyperalgesia. ABSTRACT Dexmedetomidine (Dex), an α2‐adrenergic receptor (α2‐AR) agonist, is widely used for
Hui Rong, Yang‐Xun Zhang, Huijie Zhu, Yinyao Li, Yunfan Hou, Yun‐Yong Xie, Lu‐Yao Li, Bei‐Bei Zhang, Shu‐Tao Xie, Wei Zhang, Qi‐Peng Zhang, Xiao‐Yang Zhang, Jing‐Ning Zhu, Xiaoping Gu, Zhengliang Ma   +14 more
wiley   +1 more source

<i>'It showed me that he sensed I was there. . .'</i>, The 'relational' use of an electrophysiological tool for evaluating the level of discomfort of people at the end of life: A reflexive thematic analysis. [PDF]

Palliat Med
Prod'homme C, Homey-Dusautois F, Denié M, Touzet L, Pasqualini C, Pierrat M, Puisieux F, Sabot P.   +7 more
europepmc   +1 more source

Developing a Pediatric Pain Curriculum for Pediatric Anesthesia Fellows in Sub‐Saharan Africa: A Delphi Study

Pediatric Anesthesia, Volume 36, Issue 7, Page 800-812, July 2026.
ABSTRACT Background Comprehensive pain management in children requires a specialized skillset, with a limited number of clinicians possessing the level of expertise required to successfully navigate the complexities of holistic care. The emergence of pediatric anesthesia fellowship programs in sub‐Saharan Africa presents an opportunity to embed a ...
Anisa Bhettay, Rebecca Gray, Romy Parker, Nikki Allorto, Abigail Kusi Amponsah, Brian Anderson, Lillian Baranzila, Charles Carapinha, Susan Carolus, Lionel Green‐Thompson, Onica Higgins, Sonya Kolman, O' Brien Kyololo, Gillian Lamacraft, Helen Laycock, Samuel Matula, Kutlo Mutlhobogwa, Shireen Modack, Israa Modack, Timothy Mwiti, Raymond Ndikontar, Kazeem Oshikoya, Asma Salloo, Jenny Thomas, Salome Maswime   +24 more
wiley   +1 more source