Results 161 to 170 of about 14,156 (228)

Early Pain and Sensory Dysfunction in Drug‐Naïve Parkinson's Disease: Evidence From Quantitative Sensory Testing

European Journal of Pain, Volume 30, Issue 9, October 2026.
ABSTRACT Background Pain and sensory disturbances are common non‐motor symptoms in Parkinson's disease (PD) and can occur early in the disease course, even before starting dopaminergic treatment. However, somatosensory abnormalities in drug‐naïve PD remain insufficiently characterized, particularly in the absence of dopaminergic medication effects ...
Maria Skallerup Andersen, Lorenz Martin Oppel, Boris Modrau, Kimmo Jensen, Gertrud Dam‐Dalgeir, Parisa Gazerani   +5 more
wiley   +1 more source

A TRIP‐nano killer silencing the pain pacemakers

The Journal of Physiology, EarlyView.
Elisabetta Cerbai
wiley   +1 more source

Clinical Outcomes of Photobiomodulation Therapy for Inferior Alveolar Nerve Injury: A Retrospective Analysis

Lasers in Surgery and Medicine, Volume 58, Issue 8, Page 624-636, October 2026.
ABSTRACT Objectives This retrospective study evaluated the clinical outcomes associated with a photobiomodulation therapy (PBMT) protocol in patients with inferior alveolar nerve (IAN) injury following oral and maxillofacial surgery. The study specifically investigated whether the etiology of paresthesia, the time elapsed before treatment initiation ...
Halenur Ates, Yavuz Tolga Korkmaz
wiley   +1 more source

Multimodal targets of (‐)‐α‐thujone mediating avoidance behavior of a stored‐products pest, Tribolium castaneum, in response to irritant stimuli

Pest Management Science, Volume 82, Issue 10, Page 9592-9598, October 2026.
We identified four kinds of target molecules against (‐)‐α‐thujone associating avoidance behavior in Tribolium castaneum, indicating multimodality. Abstract BACKGROUND The reciprocal evolutionary processes among phytophagous insects and host plants involve host shift in the herbivorous insects in response to defense chemicals, such as plant‐derived ...
Kenji Shimomura, Yuto Suzuki, Soshi Ino, Takehito Terajima, Motohiro Tomizawa   +4 more
wiley   +1 more source

No gain from pain: Lack of nociceptor activation suggests no adaptation for defence in the evolution of European viper venoms

Functional Ecology, Volume 40, Issue 10, Page 3048-3062, October 2026.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Snake venoms show variability in composition at all taxonomic levels, both within and between species, and the selective pressures underlying this variation have long been debated.
Bálint Üveges, Samuel D. Robinson, Vanessa Schendel, Edvárd Mizsei, Ana Ćuriċ, Maria Dimaki, Vincenzo Ferri, Silviu Petrovan, Andrea V. Pozzi, Tihomir Radonjiċ, Tibor Sos, Jeffrey W. Streicher, Alexandru Strugariu, Emina Šunje, Ștefan Zamfirescu, Oleksandr Zinenko, Irina Vetter, Wolfgang Wüster   +17 more
wiley   +1 more source

Acute Pain During Intensive Care: Prevalence, Predisposing Factors and Pain Trajectories. A Prospective Multicenter Observational Study

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 9, October 2026.
ABSTRACT Background A considerable proportion of patients in the intensive care unit (ICU) experience pain. The objective of this prospective observational cohort study was to investigate the prevalence of pain, factors associated with pain and pain trajectories in ICU patients.
Aleksandra E. Wlodarczyk‐Abou Elseoud, Maija‐Liisa Kalliomäki, Otto Mäkinen, Annika Laukkanen, Minna Bäcklund, Mitja Lääperi, Katri Hamunen, Anna‐Maria Kuivalainen   +7 more
wiley   +1 more source

β‐Catenin‐Deficient Intervertebral Disc Cells Reduce Chemotactic Transcription and Myeloid Cell Recruitment to Injured Discs of Mice

Aging Cell, Volume 25, Issue 10, October 2026.
(Left) In young discs, Wnt signaling‐replete nucleus pulposus cells secrete ECM components and, upon disc injury, cytokines to recruit myeloid cells. (Right) Whereas, β‐catenin‐deficient disc cells, modeling age‐related absence of Wnt signaling, exhibit reduced anabolic activity and, upon disc injury, secrete fewer pro‐inflammatory cytokines and ...
Tori M. Kroon, Jazz Munitz, Anna Ranzenigo, Martin Umali, William Wang, Jonathan J. Huang, Abraham J. P. Teunissen, Nilsson Holguin   +7 more
wiley   +1 more source

uPAR‐Targeting T Cell Engager Exerts Senolytic Effects in Mice and Non‐Human Primates With Serum Aminotransferase Activity as a Safety Monitor

Aging Cell, Volume 25, Issue 10, October 2026.
GFD‐CD3, a uPAR‐targeting T‐cell engager, effectively cleared senescent cells and mitigated age‐related pathologies with a favorable safety profile under transaminase‐guided monitoring. ABSTRACT Senolytic CAR‐T cells targeting uPAR induce dose‐dependent toxicities.
Jian Deng, Xiaozhu Zeng, Jing Guo, Lihong Li, Shirui Zou, Nan Liu, Shuai He, Lanzhen Yan, Qiong Wang, Yongjie Zhu, Ben Wang, Dong Yang, Longbao Lv, Xudong Zhao   +13 more
wiley   +1 more source

ZNF865 (BLST) a Novel Regulator of DNA Damage and Cell Senescence in Back Pain

Aging Cell, Volume 25, Issue 10, October 2026.
ZNF865 (BLST) has previously been classified as part of the “unknome”, but here in the context of back pain, we demonstrate the first functional characterization of ZNF865. We demonstrate that it regulates genomic stability and subsequent senescence, and that downregulation in the intervertebral disc leads to pain behavior in rodent models.
Christian Lewis, Hunter Levis, Jonah Holbrook, Jacob T. Polaski, Timothy D. Jacobsen, Josh Mizels, Molly Czachor, Sarah E. Gullbrand, Brian Diekman, James C. Iatridis, Jason Gertz, Brandon Lawrence, Robby D. Bowles   +12 more
wiley   +1 more source

The benefits of multidisciplinary collaboration in the successful management of two complex feline cases

Australian Veterinary Journal, Volume 104, Issue 10, Page 710-718, October 2026.
Despite a frequent misconception that behavioural concerns are diagnoses of exclusion, medical conditions and behavioural disorders are frequently inter‐related. In human medicine, the ‘multidisciplinary team’ approach (MDTA) is considered the most efficacious way of managing patients with complex and chronic health conditions.
BE Bollaert, JM Ley, HE Zulch
wiley   +1 more source