Results 41 to 50 of about 66,701 (144)

Mechanisms involved in the nociception triggered by the venom of the armed spider Phoneutria nigriventer.

open access: yesPLoS Neglected Tropical Diseases, 2013
BackgroundThe frequency of accidental spider bites in Brazil is growing, and poisoning due to bites from the spider genus Phoneutria nigriventer is the second most frequent source of such accidents.
Camila Gewehr   +9 more
doaj   +1 more source

Purinergic mechanosensory transduction and visceral pain [PDF]

open access: yes, 2009
In this review, evidence is presented to support the hypothesis that mechanosensory transduction occurs in tubes and sacs and can initiate visceral pain.
Burnstock, G
core   +3 more sources

Nociceptor-Enriched Genes Required for Normal Thermal Nociception

open access: yesCell Reports, 2016
Here, we describe a targeted reverse genetic screen for thermal nociception genes in Drosophila larvae. Using laser capture microdissection and microarray analyses of nociceptive and non-nociceptive neurons, we identified 275 nociceptor-enriched genes ...
Ken Honjo   +4 more
doaj   +1 more source

Genetic study in patients operated dentally and anesthetized with articaine-epinephrine [PDF]

open access: yes, 2019
Aims: In this study we wanted to figure out if there was a correlation between OPRM1 N40D, TRPV1 I316M, TRPV1 I585V, NOS3 −786T>C and IL6 −174C>G polymorphisms and the response to locally applied articaine-epinephrine anesthetic.
Cieza-Borrella, C   +5 more
core   +2 more sources

Mitogen- and stress-activated kinase 1 in primary sensory neurons contributes to formalin-induced tonic pain

open access: yesPAIN Reports
. Introduction:. The nuclear mitogen- and stress-activated kinases (MSKs) play a critical role in the development and persistence of pain after tissue injury. Objectives:. Here, we ascertained the MSK isoform, the cells and mechanisms, which mediate MSKs'
Jahanzaib Irfan   +11 more
doaj   +1 more source

Brain rhythms of pain [PDF]

open access: yes, 2017
Pain is an integrative phenomenon that results from dynamic interactions between sensory and contextual (i.e., cognitive, emotional, and motivational) processes.
Gross, Joachim   +2 more
core   +1 more source

Analgesia Nociception Index: assessment of acute postoperative pain [PDF]

open access: yesRevista Brasileira de Anestesiologia
Background and objectives Patient self-rating based scales such as Numerical Rating Scale, Visual Analog Scale that is used for postoperative pain assessment may be problematic in geriatric or critically ill patients with communication problems. A method
Ruslan Abdullayev   +2 more
doaj   +3 more sources

In vitro and in vivo pharmacological activities of 14-o-phenylpropyloxymorphone, a potent mixed mu/delta/kappa-opioid receptor agonist with reduced constipation in mice [PDF]

open access: yes, 2018
Pain, particularly chronic pain, is still an unsolved medical condition. Central goals in pain control are to provide analgesia of adequate efficacy and to reduce complications associated with the currently available drugs.
Lattanzi, Roberta   +4 more
core   +2 more sources

Nociception monitors vs. standard practice for titration of opioid administration in general anesthesia: A meta-analysis of randomized controlled trials

open access: yesFrontiers in Medicine, 2022
BackgroundNociception monitors are being increasingly used during surgery, but their effectiveness in guiding intraoperative opioid administration is still uncertain.
Dandan Ma   +6 more
doaj   +1 more source

Effect of high level of bladder filling on spinal nociception and motoneuronal excitability [PDF]

open access: yes, 2015
To verify whether high level of bladder distension may counteract the inhibitory effect of descending pathways on sacral spinal cord neurons and to investigate which spinal circuitries are possibly involved in such a viscero-somatic interaction ...
Carbone, Antonio   +10 more
core   +1 more source

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