Results 41 to 50 of about 86,806 (345)

KCNQ Channels in the Mesolimbic Reward Circuit Regulate Nociception in Chronic Pain in Mice

open access: yesNeuroscience Bulletin, 2021
Mesocorticolimbic dopaminergic (DA) neurons have been implicated in regulating nociception in chronic pain, yet the mechanisms are barely understood.
Hao-Ran Wang   +11 more
semanticscholar   +1 more source

Conditional gene deletion reveals functional redundancy of GABAB receptors in peripheral nociceptors in vivo [PDF]

open access: yes, 2009
Background Gamma-aminobutyric acid (GABA) is an important inhibitory neurotransmitter which mainly mediates its effects on neurons via ionotropic (GABAA) and metabotropic (GABAB) receptors.
Bernhard Bettler   +9 more
core   +3 more sources

Studies of the biological and therapeutic effects of argentine stingless bee propolis [PDF]

open access: yes, 2018
Meliponids are native bees of the Americas, characterized by having no sting (ANSA). Some live in the Yunga forests of northern Argentina, a place rich in a diversity of this type of bees of which at least thirty-three species may be found. Propolis is a
Brodkiewicz, Ivana Yanina   +5 more
core   +1 more source

Changes in Activity of the Same Thalamic Neurons to Repeated Nociception in Behaving Mice. [PDF]

open access: yesPLoS ONE, 2015
The sensory thalamus has been reported to play a key role in central pain sensory modulation and processing, but its response to repeated nociception at thalamic level is not well known.
Yeowool Huh, Jeiwon Cho
doaj   +1 more source

Ingested bovine amniotic fluid enhances morphine antinociception in rats [PDF]

open access: yes, 2000
Ingestion by rats of rat placenta or amniotic fluid enhances opioid-mediated, or partly opioid-mediated, antinociception produced by morphine injection, vaginal or cervical stimulation, late pregnancy, and foot shock.
Corpening, James W.   +2 more
core   +1 more source

Distinct nociception processing in the dysgranular and barrel regions of the mouse somatosensory cortex

open access: yesNature Communications, 2022
The processing of nociception in the somatosensory cortex (S1) has yet to be fully understood. Here, the authors demonstrate that the dysgranular region in S1 has an affinity for nociception and is critically involved in pain-like behavior.
Hironobu Osaki   +3 more
doaj   +1 more source

The nociceptive response induced by different classes of Tityus serrulatus neurotoxins: The important role of Ts5 in venom-induced nociception

open access: yesPLoS Neglected Tropical Diseases, 2023
Scorpion sting envenomations (SSE) are feared by the intense pain that they produce in victims. Pain from SSE is triggered mainly by the presence of neurotoxins in the scorpion venom that modulates voltage-gated ion channels.
Felipe Cerni   +8 more
doaj   +2 more sources

Mas-related G-protein–coupled receptors inhibit pathological pain in mice [PDF]

open access: yes, 2010
An important objective of pain research is to identify novel drug targets for the treatment of pathological persistent pain states, such as inflammatory and neuropathic pain.
Altier   +49 more
core   +2 more sources

Do decapod crustaceans have nociceptors for extreme pH? [PDF]

open access: yesPLoS ONE, 2010
Nociception is the physiological detection of noxious stimuli. Because of its obvious importance, nociception is expected to be widespread across animal taxa and to trigger robust behaviours reliably. Nociception in invertebrates, such as crustaceans, is
Sakshi Puri, Zen Faulkes
doaj   +1 more source

The validity and applications of the analgesia nociception index: a narrative review

open access: yesFrontiers in Surgery, 2023
Pain refers to the subjective, unpleasant experience that is related to illness or injury. In contrast to pain, nociception refers to the physiological neural processing of noxious stimuli, such as intra-operative surgical stimuli.
Bill Hum   +5 more
doaj   +1 more source

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