Results 201 to 210 of about 97,568 (259)

Ovarian pain in the mare: Clinical implications of mittelschmerz and oestrus‐related behavioural abnormalities

Equine Veterinary Education, EarlyView.
Summary Mittelschmerz is a well‐recognised benign peri‐ovulatory pain syndrome in women and, by physiological analogy, may also occur in mares. In equine practice, peri‐ovulatory ovarian pain has been associated with transient discomfort, colic‐like signs and behavioural changes, although its true clinical relevance remains poorly defined.
G. Marino, V. Biondi, A. Sfacteria, G. Catone, C. Vullo   +4 more
wiley   +1 more source

Mixed Pain: Toward a Consensus Definition and a Mechanism-Based Framework. [PDF]

Eur J Pain
Freynhagen R, Morlion B, Alcántara Montero A, Ciampi de Andrade D, Hernández-Ortiz A, Hodges PW, Nimmaanrat S, Pogatzki-Zahn EM, Raff M, Rey RD, Tesfaye S, Truini A, Varrassi G, Baron R.   +13 more
europepmc   +1 more source

Persistent in vitro nociceptor hyperexcitability and axonal retraction produced by repeated paclitaxel doses

The FEBS Journal, EarlyView.
Repeated paclitaxel exposure causes long‐lasting nociceptor hyperexcitability and axonal retraction in adult sensory neurons. Using a long‐term primary nociceptor culture, we show that hyperexcitability is mediated by sequential upregulation of NaV1.8, TRPV1, TRPA1, and TRPM8 channels.
Angela Lamberti, Victor Moreno Lozano, Asia Fernández‐Carvajal, Antonio Ferrer‐Montiel   +3 more
wiley   +1 more source

BDNF-TrkB Signaling Engages a Src Family Kinase-Pannexin 1 Pathway During the Onset of Sustained Mechanical Hyperalgesia. [PDF]

Int J Mol Sci
Aránguiz Barrera J, Moreira-Banuth AM, Zepeda-Morales K, Triolo M, Oneto NI, Bravo D, Huidobro-Toro JP, Donoso MV, Noseda R, Pelissier T, Hernández A, Constandil L, Retamal JS.   +12 more
europepmc   +1 more source

Novel targets in headache: A narrative review

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Objectives/Background This narrative review summarizes novel applications for the use of calcitonin gene‐related peptide (CGRP)‐targeted therapies that go beyond migraine, the latest updates with respect to targeting pituitary adenylate cyclase‐activating peptide (PACAP) as therapeutic in migraine, as well as exploring other more recently ...
Adriana Della Pietra, Peter J. Goadsby, Carolina Oldoni, Stephen Silberstein, Fred Cohen, Simon Akerman   +5 more
wiley   +1 more source

Anti-Inflammatory and Analgesic Properties of <i>Polygonum minus</i>: Mechanistic Insights and Therapeutic Potential. [PDF]

Biomedicines
Kamaruzzaman MA, Ruslan R, Mohd Isa IL, Kamaruddin NA, Mohd Ramli ES.   +4 more
europepmc   +1 more source

Orofacial pain disorder or trigeminal autonomic cephalalgia? Insights into pathophysiology and implications in medicine and dentistry

Headache: The Journal of Head and Face Pain, EarlyView.
There are some headache disorders known as trigeminal autonomic cephalalgias (TACs). When these “headaches” are localized in the mid‐face region, they are known as “trigeminal autonomic orofacial pains” (TAOPs), and they can mimic other types of face pains including dental pain, which puts the patient at risk of receiving treatments that are incorrect.
Marcela Romero‐Reyes, Simon Akerman
wiley   +1 more source

Conformable thin-film cuff electrodes as tools for peripheral nerve recording: a comparative study. [PDF]

Front Neurosci
Güemes A, Forner MOA, Guindo-Arroyo A, Serrano RR, Malliaras GG, Carnicer-Lombarte A.   +5 more
europepmc   +1 more source

The Expression of Neuropeptides in Pulpitis: A Systematic Review and Meta‐Analysis

International Endodontic Journal, EarlyView.
ABSTRACT Background Neuropeptides play key roles in the inflammatory, nociceptive and reparative processes of the dental pulp. Their upregulation has been frequently observed in inflamed pulps, suggesting potential diagnostic value supporting a role for neurogenic inflammation in symptomatic irreversible pulpitis.
N. Watson, D. Edwards, Q. Vuong, I. Obara   +3 more
wiley   +1 more source