Neurobiology of Pain, 2023 Objective: Alterations in autonomic function are evident in some chronic pain conditions but have not been thoroughly examined in people with osteoarthritis (OA).
Neil R. Bossenger +3 more
doaj +1 more source
Visually induced analgesia: seeing the body reduces pain [PDF]
, 2009 Given previous reports of strong interactions between vision and somatic senses, we investigated whether vision of the body modulates pain perception. Participants looked into a mirror aligned with their body midline at either the reflection of their own
Longo, Matthew R. +9 more
core +1 more source
Quantifying cerebral contributions to pain beyond nociception
Nature Communications, 2017 Pain is affected by cerebral processes in addition to afferent nociceptive input. Here the authors develop an fMRI-based signature that predicts pain independent of the intensity of nociceptive signals and mediates the pain-modulating effects of several ...
Choong-Wan Woo +7 more
doaj +1 more source
Comparative Physiology of Nociception and Pain [PDF]
Physiology, 2018 The study of diverse animal groups allows us to discern the evolution of the neurobiology of nociception. Nociception functions as an important alarm system alerting the individual to potential and actual tissue damage. All animals possess nociceptors, and, in some animal groups, it has been demonstrated that there are consistent physiological ...
openaire +2 more sources
Pain hypersensitivity and spinal nociceptive hypersensitivity in chronic pain: prevalence and associated factors. [PDF]
, 2015 Hypersensitivity of pain pathways is considered a relevant determinant of symptoms in chronic pain patients, but data on its prevalence are very limited. To our knowledge, no data on the prevalence of spinal nociceptive hypersensitivity are available. We
Andersen, Ole Kæseler; id_orcid +8 more
core +1 more source
Human psychophysiological responses to visceral and somatic pain – the development of integrated, reproducible human pain phenotypes [PDF]
, 2011 PhDBackground Pain is the ubiquitous human experience, yet displays considerable inter- and intraindividual variability in health and disease. Many factors have been proposed to account for these differences.
Farmer, Adam Donald
core +4 more sources
Myofascial Pain Syndrome: A Nociceptive Condition Comorbid with Neuropathic or Nociplastic Pain
Life, 2023 Myofascial pain syndrome is featured by the presence of myofascial trigger points (TrPs). Whether TrPs are primary or secondary phenomena or if they relate to central or peripheral nervous system disorders is controversial. Referred pain, a cardinal sign
César Fernández-de-las-Peñas +6 more
doaj +1 more source
Complex Regional Pain Syndrome: Why Does Pain Spread From the Injured Limb to the Face? [PDF]
, 2009 In patients with complex regional pain syndrome (CRPS), sensory disturbances commonly spread outside the affected limb, in particular hemilaterally. Hyperalgesia to pressure-pain was, for instance, documented in the forehead ipsilateral to the affected ...
Knudsen, Lone
core
Descending serotonergic controls regulate inflammation-induced induced mechanical sensitivity and methyl-CpG-binding protein 2 phosphorylation in the rat superficial dorsal horn [PDF]
, 2008 Background: Regulation of pain states is, in part, dependent upon plastic changes in neurones within the superficial dorsal horn. There is also compelling evidence that pain states are under the control of descending projections from the brainstem. While
Geranton, SM +11 more
core +1 more source
Single and double pain responses to individually titrated ultra-short laser stimulation in humans
BMC Anesthesiology, 2019 Background This preclinical study in humans was designed to selectively induce delayed nociceptive pain responses to individually titrated laser stimulation, enabling separate bedside intensity scoring of both immediate and delayed pain.
Anna Sellgren Engskov +2 more
doaj +1 more source