Results 41 to 50 of about 1,073,273 (204)

Fibromyalgia is associated with hypersensitivity but not with abnormal pain modulation: evidence from QST trials and spinal fMRI

Frontiers in Pain Research, 2023
Widespread pain and hyperalgesia are characteristics of chronic musculoskeletal pain conditions, including fibromyalgia syndrome (FM). Despite mixed evidence, there is increasing consensus that these characteristics depend on abnormal pain augmentation ...
Roland Staud, Melyssa M. Godfrey, Patrick W. Stroman   +2 more
doaj   +1 more source

Pain relief is associated with decreasing postural sway in patients with non-specific low back pain [PDF]

, 2012
Background Increased postural sway is well documented in patients suffering from non-specific low back pain, whereby a linear relationship between higher pain intensities and increasing postural sway has been described.
Walker Bruce, Ruhe Alexander, Alexander Ruhe, Ruhe, A., Bruce Walker, Walker, B., Fejer, R., Fejer René, René Fejer, Fejer, René   +9 more
core   +2 more sources

Endocannabinoids Have Opposing Effects On Behavioral Responses To Nociceptive And Non-nociceptive Stimuli

Scientific Reports, 2017
The endocannabinoid system is thought to modulate nociceptive signaling making it a potential therapeutic target for treating pain. However, there is evidence that endocannabinoids have both pro- and anti-nociceptive effects.
Torrie Summers, Brandon Hanten, Warren Peterson, Brian Burrell   +3 more
doaj   +1 more source

Controlling attention to nociceptive stimuli with working memory. [PDF]

PLoS ONE, 2011
BACKGROUND: Because pain often signals the occurrence of potential tissue damage, a nociceptive stimulus has the capacity to involuntarily capture attention and take priority over other sensory inputs.
Valéry Legrain, Geert Crombez, André Mouraux   +2 more
doaj   +1 more source

Central Sensitization in Patients with Chronic Musculoskeletal Pain

Acta Clinica Croatica, 2023
Central sensitization is the mechanism of nociplastic pain and leads to an overemphasized response to a painful stimulus (hyperalgesia) or pain to stimuli that do not otherwise cause pain (allodynia).
Snežana Tomašević-Todorović, Tijana Spasojević   +1 more
doaj   +1 more source

Sensory changes in the forehead of patients with complex regional pain syndrome [PDF]

, 2006
The aim of this study was to investigate involvement of central mechanisms in complex regional pain syndrome (CRPS). In particular, we wished to determine whether hyperalgesia extends ipsilaterally from the affected limb to the forehead.
Drummond, P.D., Finch, P.M.
core  

Soluble epoxide hydrolase limits mechanical hyperalgesia during inflammation [PDF]

, 2011
Background Cytochrome-P450 (CYP450) epoxygenases metabolise arachidonic acid (AA) into four different biologically active epoxyeicosatrienoic acid (EET) regioisomers.
Geisslinger, Gerd, Gerd Geisslinger, Brandes, Ralf P., Brandes, Ralf, Michael J Fischer, Fleming, Ingrid, Scholich, Klaus, Woolf Clifford J, Ralf P Brandes, Clifford J Woolf, Fleming Ingrid, Reeh, Peter Werner, Brenneis Christian, Fischer, Michael, Coste Ovidiu, Coste, Ovidiu, Brandes Ralf P, Kai Altenrath, Reeh Peter W, Christian Brenneis, Scholich Klaus, Sisignano, Marco, Reeh, Peter W., Altenrath Kai, Ingrid Fleming, Peter W Reeh, Woolf, Clifford J., Angioni Carlo, Geisslinger Gerd, Angioni, Carlo Federico, Klaus Scholich, Brenneis, Christian, Ovidiu Coste, Carlo Angioni, Sisignano Marco, Marco Sisignano, Fischer, Michael J., Fischer Michael J, Altenrath, Kai, Angioni, Carlo   +39 more
core   +3 more sources

An fMRI study exploring the overlap and differences between neural representations of physical and recalled pain.

PLoS ONE, 2012
Implementing a recall paradigm without hypnosis, we use functional MRI (fMRI) to explore and compare nociceptive and centrally-driven pain experiences. We posit that a trace of a recent nociceptive event can be used to create sensory-re-experiencing of ...
Merle Fairhurst, Katherine Fairhurst, Chantal Berna, Irene Tracey   +3 more
doaj   +1 more source

Linking pain and the body: neural correlates of visually induced analgesia [PDF]

, 2012
The visual context of seeing the body can reduce the experience of acute pain, producing a multisensory analgesia. Here we investigated the neural correlates of this “visually induced analgesia” using fMRI.
Longo, Matthew R., Iannetti, GD, Longo, M, Iannetti, G.D., Longo, MR, Haggard, P, Driver, J., ,, Mancini, F, Mancini, F., Haggard, P., Driver, J   +11 more
core   +1 more source

The Phytochemical, Quercetin, Attenuates Nociceptive and Pathological Pain: Neurophysiological Mechanisms and Therapeutic Potential

Molecules
Although phytochemicals are plant-derived toxins that are primarily produced as a form of defense against insects or microbes, several lines of study have demonstrated that the phytochemical, quercetin, has several beneficial biological actions for human
Mamoru Takeda, Yukito Sashide, Ryou Toyota, Haruka Ito   +3 more
doaj   +1 more source