Results 51 to 60 of about 1,073,273 (204)

KCNQ/M currents in sensory neurons: Significance for pain therapy [PDF]

, 2003
Neuronal hyperexcitability is a feature of epilepsy and both inflammatory and neuropathic pain. M currents [I-K(M)] play a key role in regulating neuronal excitability, and mutations in neuronal KCNQ2/3 subunits, the molecular correlates of I-K(M), have ...
Main, M, Matthews, EA, Burbidge, SA, Brown, TA, Brown, DA, Passmore, GM, Marsh, SJ, Mistry, M, Selyanko, AA, Al-Qatari, M, Dickenson, AH   +10 more
core  

Pain Type and Quality of Life in Cervicogenic Headache Patients

Aksona
Highlight: • Cervicogenic headache is the most incapacitating type, leading to significant physical impairment. • Based on the data, there were 15 subjects in the nociceptive pain group and 15 subjects in the neuropathic pain group.
Devi Ariani Sudibyo, M Reza Fathoni, Nazla Ananda Rachmi Puti   +2 more
doaj   +1 more source

Back pain

Pediatria i Medycyna Rodzinna, 2014
Back pain is a symptom of a number of underlying diseases. The pain syndrome may be due to disorders of bone structures, apophyseal joints, ligaments, fascia, muscles or intervertebral discs, subsequently affecting or not the spinal cord and peripheral
Iwan Milanow
doaj   +1 more source

Post-surgical contributors to persistent knee pain following knee replacement: The Multicenter Osteoarthritis Study (MOST)

Osteoarthritis and Cartilage Open, 2023
Objective: Pain persistence following knee replacement (KR) occurs in ∼20–30% of patients. Although several studies have identified preoperative risk factors for persistent post-KR pain, few have focused on post-KR contributing factors.
Kosaku Aoyagi, Laura Frey Law, Lisa Carlesso, Michael Nevitt, Cora E. Lewis, Na Wang, Tuhina Neogi   +6 more
doaj   +1 more source

Nociceptor mechanisms underlying pain and bone remodeling via orthodontic forces: toward no pain, big gain

Frontiers in Pain Research
Orthodontic forces are strongly associated with pain, the primary complaint among patients wearing orthodontic braces. Compared to other side effects of orthodontic treatment, orthodontic pain is often overlooked, with limited clinical management ...
Sheng Wang, Ching-Chang Ko, Man-Kyo Chung, Man-Kyo Chung   +3 more
doaj   +1 more source

NO Pain! No Cancer? The Crosstalk Between Nociception, ROS, and Cancer Development

Frontiers in Bioscience-Landmark
Transient receptor potential (TRP) channels, particularly those involved in nociception (nociceptive TRP channels), are implicated in both pain and cancer development.
Tzu-Yin Chen, Tohru Yoshioka, Wen-Li Hsu
doaj   +1 more source

Nociception and pain in the electroencephalogram

, 2023
The scope of this thesis is to elaborate on the use cases of the EEG in pain research. It has been submitted as a cumulative dissertation, meaning that the main part of this thesis has been previously published in international peer-reviewed journals.
openaire   +2 more sources

Sensory disturbances in complex regional pain syndrome: Clinical observations, autonomic interactions, and possible mechanisms [PDF]

, 2010
To review mechanisms that might contribute to sensory disturbances and sympathetically-maintained pain in complex regional pain syndrome (CRPS). CRPS is associated with a range of sensory and autonomic abnormalities.
Drummond, P.D.
core  

R-flurbiprofen reduces neuropathic pain in rodents by restoring endogenous cannabinoids [PDF]

, 2010
Background: R-flurbiprofen, one of the enantiomers of flurbiprofen racemate, is inactive with respect to cyclooxygenase inhibition, but shows analgesic properties without relevant toxicity. Its mode of action is still unclear.
Geisslinger, Gerd, Gerd Geisslinger, Ziebell Simone, Julia Metzner, Ziebell, Simone, Koch, Marco, Myrczek, Thekla, Marian, Claudiu, Dehghani, Faramarz, Rohini Kuner, Schmidt Helmut, Bechmann Ingo, Marian Claudiu, Nina Wijnvoord, Dehghani Faramarz, Philipp Bishay, Bishay, Philipp, Kuner, Rohini, Helmut Schmidt, Faramarz Dehghani, Koch Marco, Bechmann, Ingo, Metzner, Julia, Geisslinger Gerd, Irmgard Tegeder, Tegeder Irmgard, Simone Ziebell, Wijnvoord, Nina, Tegeder, Irmgard, Claudiu Marian, Kuner Rohini, Costigan, Michael, Wijnvoord Nina, Annett Häussler, Ingo Bechmann, Michael Costigan, Schmidt, Helmut, Häussler, Annett, Bechmann, Ingo Jürgen, Myrczek Thekla, Bishay Philipp, Häussler Annett, Marco Koch, Costigan Michael, Thekla Myrczek, Metzner Julia   +45 more
core   +1 more source

Dietary linoleic acid-induced alterations in pro- and anti-nociceptive lipid autacoids

Molecular Pain, 2016
Background Chronic idiopathic pain syndromes are major causes of personal suffering, disability, and societal expense. Dietary n-6 linoleic acid has increased markedly in modern industrialized populations over the past century.
Christopher E Ramsden MD, Amit Ringel BS, Sharon F Majchrzak-Hong MS, Jun Yang PhD, Helene Blanchard PhD, Daisy Zamora PhD, James D Loewke BS, Stanley I Rapoport MD, Joseph R Hibbeln MD, John M Davis MD, Bruce D Hammock PhD, Ameer Y Taha PhD   +11 more
doaj   +1 more source