Results 51 to 60 of about 1,002,831 (175)

Retrospective Analysis of Functional Pain among Professional Climbers

Applied Sciences, 2022
Climbing became one of the official Olympic sports in 2020. The nociplastic pain mechanism is indicated as important in professional sports. Functional pain, which has not been examined in climbers until now, can be an example of nociplastic pain.
Matuska Jakub, Jokiel Marta, Domaszewski Przemysław, Konieczny Mariusz, Pakosz Paweł, Dybek Tomasz, Wotzka Daria, Skorupska Elżbieta   +7 more
doaj   +1 more source

Microglial Activation in Nociplastic Pain: From Preclinical Models to PET Neuroimaging and Implications for Targeted Therapeutic Strategies. [PDF]

Int J Mol Sci
Nociplastic pain has recently been introduced as a third entity for identifying patients suffering from chronic pain that arises from altered nociception, without evidence of peripheral nociceptors activation or alterations of the somatosensory system ...
Coluzzi F, Zeboudj L, Scerpa MS, Giorgio A, De Blasi RA, Malcangio M, Rocco M.   +6 more
europepmc   +2 more sources

High Prevalence and Clinical Impact of Fibromyalgia in Functional Motor Disorder

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Fibromyalgia is characterized by widespread pain, fatigue, sleep and cognitive symptoms. It overlaps clinically with functional motor disorder (FMD), yet its prevalence and impact in FMD remain uncertain. Objective To determine the prevalence of fibromyalgia in FMD using the current criteria and evaluate its effects on motor ...
Tereza Serranová, Lucia Nováková, Martin Jirásek, Barbora Křupková, Evžen Růžička, Michele Tinazzi, Tomáš Sieger   +6 more
wiley   +1 more source

Towards a better definition of nociplastic pain conditions: a psychological grounded study on fibromyalgia, chronic headache and vulvodynia

European Journal of Psychotraumatology
Background: This study investigates the psychological underpinnings of chronic pain conditions, specifically fibromyalgia, chronic headache, vulvodynia, and mixed condition (consisting of fibromyalgia in comorbidity with chronic headache and/or ...
Martina Mesce, Filippo Maria Nimbi, Piercarlo Sarzi-Puttini, Carlo Lai, Federica Galli   +4 more
doaj   +1 more source

Cannabis‐Based Oil for Pain and Other Non‐Motor Symptoms in Parkinson's Disease: A Randomized Controlled Trial

Movement Disorders, EarlyView.
Abstract Background There is a lack of treatments for non‐motor symptoms (NMS) in Parkinson's disease (PD). Objective To assess the safety and effectiveness of an oral Cannabis sativa L. extract on pain and other NMS of PD. Methods This phase II, randomized, placebo‐controlled trial evaluated a formulation containing cannabidiol (CBD; 96 mg/ml) and Δ9 ...
Gabriel T. Kubota, Jacy B. Parmera, Matheus Deltreggia, Pedro N. Martins, Anna Letícia M. Alves, Ananda C.M. de Falcone, Ana Rosa Santana, Maria Alice P. Falcão, Mayara A. Dias, Larissa I. Moreira, Paulo C. de Fonseca Filho, Eberval G. Figueiredo, Egberto R. Barbosa, Rubens G. Cury, Daniel C. de Andrade   +14 more
wiley   +1 more source

Effect of pain management, supervised exercise, and pelvic floor muscle training on sexual function in women with endometriosis: A randomized controlled trial

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
A multimodal intervention including supervised exercise, pelvic floor muscle training, and pain management was associated with modest short‐term improvements in sexual function among women with endometriosis. Findings should be interpreted cautiously due to differences in sexual activity status between groups.
Rakel Gabrielsen, Tina Tellum, Kari Bø, Marie Ellström Engh, Merete Kolberg Tennfjord   +4 more
wiley   +1 more source

Part of pain labelled neuropathic in rheumatic disease might be rather nociplastic

RMD Open, 2020
Pain in rheumatic diseases is primarily due to mechanical or inflammatory mechanism, but neuropathic pain (NP) component is also occurring in many conditions and is probably underdiagnosed.
Alain Cantagrel, Anne-Priscille Trouvin, Serge Perrot, Daniel Wendling, Florian Bailly, Philippe Bertin, Thierry Thomas, Thibaud Lansaman, Laurent Grange, Calogera Dovico   +9 more
doaj   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Pain in Inflammatory and Degenerative Joint Diseases

Journal of Clinical Rheumatology and Immunology
The International Association for the Study of Pain (IASP) agreed in 2020 on a revised definition of pain: “An unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage”.
Hilde Berner Hammer
doaj   +1 more source

The putative role of immune-inflammatory mechanisms in nociplastic pain pathways: a narrative review [PDF]

Exploration of Immunology
Nociplastic pain is the fourth category of pain defined in recent years. It is a pain arising from altered nociception, despite the lack of clear evidence of actual or threatened tissue damage that causes activation of peripheral nociceptors nor evidence
Mariateresa Giglio, Alberto Corriero, Angela Preziosa, Giustino Varrassi, Filomena Puntillo   +4 more
doaj   +1 more source