Results 81 to 90 of about 1,002,831 (175)

Measuring muscle tone and pain in children with cerebral palsy: Pain that does not interfere is still pain

Developmental Medicine &Child Neurology, EarlyView.
Sarah Kim, Edward Hurvitz
wiley   +1 more source

A nociceptive-nociplastic spectrum of myofascial orofacial pain: insights from neuronal ion channel studies

Frontiers in Cellular Neuroscience
Myofascial orofacial pain, traditionally viewed as a nociceptive pain condition, also exhibits characteristics consistent with nociplastic pain—pain arising from altered nociception without clear evidence of tissue damage.
Nontawat Chuinsiri, Nontawat Chuinsiri, Watcharaphol Tiskratok, Watcharaphol Tiskratok, Teekayu Plangkoon Jorns   +4 more
doaj   +1 more source

Nociplastic pain: challenges and future perspectives

BrJP
Felipe J. J. Reis, Thais Cristina Chaves
doaj   +3 more sources

Nociplastic Pain: A Contemporary Narrative Review of Mechanisms, Clinical Assessment, Controversies, and Management

Journal of Pain Research
Chin-Chen Chu,1 Yao-Tsung Lin,2 Jhi-Joung Wang11Department of Anesthesiology, Chi Mei Medical Center, Tainan, Taiwan; 2Department of Anesthesiology, Chi Mei Hospital, Chiali, Tainan, TaiwanCorrespondence: Jhi-Joung Wang, Department of Anesthesiology, Chi
Chu CC, Lin YT, Wang JJ
doaj  

The insula represents a key neurobiological pain hub in psoriatic arthritis

Arthritis Research & Therapy
Background Pain remains a principal complaint for people with psoriatic arthritis (PsA), despite successful mitigation of inflammation. This situation alludes to the co-existence of distinct pain mechanisms.
Flavia Sunzini, Kristian Stefanov, Salim Al-Wasity, Chelsea Kaplan, Andrew Schrepf, Noah Waller, Steven Harte, Richard Harris, Daniel J. Clauw, John McLean, Stefan Siebert, Carl S. Goodyear, Gordon D. Waiter, Neil Basu   +13 more
doaj   +1 more source

Parabrachial neurons promote nociplastic pain

Trends in Neurosciences
The parabrachial nucleus (PBN) in the dorsal pons responds to bodily threats and transmits alarm signals to the forebrain. Parabrachial neuron activity is enhanced during chronic pain, and inactivation of PBN neurons in mice prevents the establishment of neuropathic, chronic pain symptoms.
openaire   +2 more sources

Recently introduced IASP definition of ‘nociplastic pain’ needs better formulation

, 2018
This is a Letter to Editor of _Pain_ recommending revision of a pain term ('nociplastic pain') recently added to the IASP Pain Terms. (With a response from the Taxonomy Committee, Eva Kosek et al.
Aydede, Murat, Shriver, Adam
core   +3 more sources

Early life social isolation stress and pain vulnerability: unraveling neuroimmune mechanisms and central sensitization

Frontiers in Pharmacology
Chronic pain is increasingly recognized as a multidimensional condition in which neuroimmune interactions shape disease vulnerability and persistence.
Carmela Belardo, Carmela Belardo, Maria Consiglia Trotta, Federica Ricciardi, Michela Perrone, Andrea Maria Morace, Rebecca Limongelli, Roozbe Bonsale, Erika D’Agostino, Emanuele Di Martino, Antimo Fusco, Silvia Natoli, Silvia Natoli, Francesca Guida, Sabatino Maione, Livio Luongo   +15 more
doaj   +1 more source

Incapacitating pain in Parkinson’s disease: A case report

Annals of Movement Disorders
Pain is an important manifestation of Parkinson’s Disease, with multiple mechanisms independently contributing to it. Here, we describe a case with predominant nociplastic pain.
Agam Jain, Pritam Raja, Seena Vengalil, Ravindranadh Chowdary, Nalini Atchayaram, Ravi Yadav   +5 more
doaj   +1 more source

Pharmacologic Management of Pain in Children: Balancing Evidence, Safety, and Clinical Challenges

Children
Pain in children remains frequently underrecognized and undertreated despite significant advances in pediatric analgesia. The pharmacologic management of pediatric pain is challenging due to developmental differences in pharmacokinetics and ...
Gianmarco Marcianò, Antonio Leo, Maria Cristina Caroleo, Riccardo Torta, Vincenzo Rania, Cristina Vocca, Caterina Palleria, Lucia Muraca, Alessandro Casarella, Domenica Scumaci, Luca Gallelli   +10 more
doaj   +1 more source